PRIDE Academy: Impact of Ancestry and Gender to omics of lung diseases

PRIDE Academy：血统和性别对肺部疾病组学的影响

• 批准号: 10077882
• 负责人: Kathleen C Barnes
• 金额: $ 46.98万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-01-07 至 2023-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10077882
• 关键词: Academia; Academy; Affect; Aggressive behavior; Americas; Asthma; Award; Biomedical Research; Capital; Collaborations; Colorado; Communities; Community of Practice; Complement; Complex; Conscious; Data Set; Databases; Disease; Educational Status; Educational workshop; Ensure; Evaluation; Expenditure; Exposure to; Extramural Activities; Face; Faculty; Failure; Feeling; Funding; Gender; Genetic; Genomics; Goals; Graduate Degree; Grant; Institutes; Instruction; Lung; Lung diseases; Manuscripts; Measures; Medical; Mentors; Methodology; Minority; Modeling; Pathogenesis; Performance; Physicians; Population; Positioning Attribute; Postdoctoral Fellow; Process; Proteomics; Pulmonary Emphysema; Pulmonary Fibrosis; Pulmonary Heart Disease; Pulmonary Hypertension; Pulmonology; Research; Research Personnel; Science; Scientist; Sex Bias; Social Sciences; Student Persistence; Study Section; Talents; Taxation; Technology; Testing; Touch sensation; Training; Travel; Underrepresented Minority; Underrepresented Populations; Underserved Population; Universities; Vision; Writing; biomedical informatics; career development; cohesion; cohort; cultural competence; disease disparity; experience; faculty mentor; hands on instruction; health disparity; holistic approach; implicit bias; interest; meetings; member; personalized medicine; precision genomic medicine; precision medicine; pressure; programs; senior faculty; social; success; summer institute; symposium; theories; tool; tool development; unconscious bias

PROJECT ABSTRACT This is a new application for a “PRIDE Academy: Impact of Ancestry and Gender on omics of lung diseases” whose objective is to introduce scholars from under-represented backgrounds to omics of lung diseases with a focus on how datasets should be interpreted and applied when working with under-represented populations. This academy will be housed at the Pulmonary and Biomedical Informatics and Personalized Medicine (BiPM) Divisions at Anschutz Medical Campus in Colorado. The Pulmonary Division has a distinguished historical record of training leaders in pulmonary medicine and the relatively new BiPM Division has been instrumental in elucidating to what extent genetics can explain health disparities in complex diseases, particularly asthma. We propose a PRIDE summer academy that will include didactic and hands-on workshops in genomics and proteomics of lung diseases such as asthma, emphysema, pulmonary fibrosis, and pulmonary hypertension. The PRIDE scholars will be assigned a mentoring team closely aligned with the mentees’ research interests. Here, in addition to the usual didactic and hands-on activities, we propose an additional level of training that uses the concept of academic “coaches”. A coach is not intended to supplant the mentor, but rather complement this relationship, since coaches do not interact with the scholars one-on-one but rather as a group. The coach will guide team members through the process of successfully navigating the academic world using well-tested social science approaches. The overall objectives are to select talented underrepresented junior faculty scholars with a demonstrated interest in pulmonary diseases; introduce the scholars to a toolkit including a mentoring team, instruction on “omics” of cardio-pulmonary diseases and a suite of social science theories for academic persistence; pair coaches with scholars to ensure that all the milestones are achieved; provide scholars with grant-writing workshops and mock study sections that will position them to compete for intramural and extramural grants; implement an evaluation plan that measures the degree to which the program is achieving its objectives. Scholars will travel to Denver for the PRIDE summer academies for 2 consecutive years and to Aspen for a face-to-face mid-year meeting at the Annual Tom Petty Aspen Lung Conference. By using the combination of coaching and social science practices such as cultural capital and communities of practice that allow team members to feel connected with each other, and pairing the scholars with distinguished pulmonary and BiPM faculty mentors, we will ensure their academic persistence and ultimate success.

项目摘要 这是“骄傲学院：祖先和性别对肺部OMIC的影响”的新应用 疾病”的目的是将来自代表性不足的背景的学者引入肺部的OMIC 疾病的重点是如何在代表性不足的情况下解释和应用数据集 人群。该学院将安置在肺和生物医学信息学上，并个性化 科罗拉多州安索茨医学校园的医学（BIPM）部门。肺部有一个 肺部医学训练领导者和相对新的BIPM部门的杰出历史记录 一直在阐明遗传学可以解释复杂疾病中的健康分布的多大程度上发挥作用， 特别是哮喘。我们提出了一个骄傲的夏季学院，其中包括教学和动手讲习班 在肺部疾病的基因组和蛋白质组学中，例如哮喘，肺气肿，肺纤维化和肺部 高血压。骄傲学者将被分配一个与Mentores研究密切一致的指导团队 利益。在这里，除了通常的教学和实践活动外，我们还提出了一个额外的水平 使用学术“教练”概念的培训。教练不是要取代精神，而是要取代 补充这种关系，因为教练不是一对一与学者互动，而是作为一个小组。 教练将指导团队成员通过使用 经过良好测试的社会科学方法。总体目标是选择有才华的人数不足的初级 对肺部疾病的兴趣表现出兴趣的学者；向学者介绍一个工具包 一支心理团队，关于心脏肺部疾病的“ OMIC”的指示以及一套社会科学理论 学术持久性；与学者配对，以确保实现所有里程碑；提供 带有赠款写作研讨会和模拟研究部分的学者，将其定位为室内竞争 和壁外赠款；实施一个评估计划，以衡量该计划的实现程度 它的目标。学者将连续2年前往丹佛，参加骄傲的夏季学院 阿斯彭（Aspen）在一年一度的汤姆·佩蒂·阿斯彭（Tom Petty Aspen）肺部会议上举行面对面的会议。通过使用 教练和社会科学实践的结合，例如文化资本和实践社区 允许团队成员感到彼此联系，并将学者与杰出的肺部配对 和BIPM教师的导师，我们将确保他们的学术毅力和最终成功。