The UCSF Brain Health Assessment for the Detection of Cognitive Impairment Among Diverse Populations in Primary Care
加州大学旧金山分校大脑健康评估,用于检测初级保健中不同人群的认知障碍
基本信息
- 批准号:10100827
- 负责人:
- 金额:$ 7.28万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-04-01 至 2022-03-31
- 项目状态:已结题
- 来源:
- 关键词:AddressAffectAgingAlzheimer&aposs DiseaseAmericanAwardBehaviorCaliforniaChinese AmericanClinicalCognitiveComputer softwareDataData CollectionData Storage and RetrievalDeliriumDementiaDetectionDevelopmentDiagnosisDiagnosticDifferential DiagnosisEarly DiagnosisEconomicsEducationEducational BackgroundEducational MaterialsElderlyEvaluationFamilyFeedbackFocus GroupsFrequenciesFundingGoalsImpaired cognitionIndividualInternationalLanguageLatinoMeasuresMedicalMemoryNeurocognitiveNeurocognitive DeficitNeuropsychological TestsNeuropsychologyPaste substancePatientsPersonsPhysiciansPopulation HeterogeneityPrimary Health CareProcessProviderPublic HealthReportingResearchResearch PersonnelSamplingSan FranciscoSecureSensitivity and SpecificitySignal TransductionSpecificitySpeedSurveysTablet ComputerTabletsTestingUnited StatesUniversitiesValidationVisuospatialWorkbrain healthclinical research sitecognitive testingcohortcommunity settingdesignethnic diversityexecutive functionfollow-uphealth assessmenthealth disparityimplementation scienceimplementation strategyimprovedinformantmedical specialtiesneurocognitive disorderperformance testsskillsstability testinguser-friendlyvalidation studies
项目摘要
PROJECT SUMMARY / ABSTRACT
Efficient and user-friendly neurocognitive screens are needed that are sensitive to the variety of neurocognitive
disorder presentations to primary care. The UCSF Brain Health Assessment was developed to efficiently
measure the cognitive domains that can be affected in the earliest stages of neurocognitive decline, including
memory, executive functions / speed, visuospatial skills, language, behavior, and function. Four subtests and
an optional informant survey are administered via an appealing tablet interface and with automated scoring
and provider feedback. Preliminary validation studies indicate excellent combined sensitivity and specificity to
cognitive impairment among English-speaking older adults with moderate to high levels of education. The
primary goals of the proposed work are to optimize and validate the BHA for older adults who are diverse in
terms of education and language spoken, to perform cross-validation studies of other paradigms funded by this
award, and to evaluate and address barriers to detecting cognitive impairment in primary care. Education and
English as a second language each impact cognitive test performance and are barriers to accurate detection of
cognitive impairment. This project will address these health disparities by including persons with diverse levels
of education and persons whose primary language is Spanish, Mandarin, or Cantonese in both validation and
implementation studies. In Aim 1, we will evaluate the validity of the BHA for the detection of cognitive
impairment in well-characterized and expertly diagnosed English-speaking older adults with low, moderate, or
high education. In Aim 2, we will evaluate the validity of the BHA for the detection of cognitive impairment in
well-characterized and expertly diagnosed Spanish-, Cantonese-, or Mandarin-speaking older adults. In Aim 3,
we will identify and address implementation challenges in primary care practices that serve patients diverse in
terms of education and language spoken. If successful, this project will lead to increased detection of cognitive
impairment in everyday community settings, which is essential to enable differential diagnosis and to improve
medical management for people with cognitive impairment, including dementia, in the United States.
项目摘要/摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Katherine Laurel Possin其他文献
Katherine Laurel Possin的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Katherine Laurel Possin', 18)}}的其他基金
The Care Ecosystem Response to COVID-19: Accelerating Research on Dementia Care that Meets the Needs of Caregivers and Persons with Dementia during COVID-19
护理生态系统对 COVID-19 的响应:加速痴呆症护理研究,满足 COVID-19 期间护理人员和痴呆症患者的需求
- 批准号:
10324344 - 财政年份:2022
- 资助金额:
$ 7.28万 - 项目类别:
The Care Ecosystem Response to COVID-19: Accelerating Research on Dementia Care that Meets the Needs of Caregivers and Persons with Dementia during COVID-19
护理生态系统对 COVID-19 的响应:加速痴呆症护理研究,满足 COVID-19 期间护理人员和痴呆症患者的需求
- 批准号:
10634511 - 财政年份:2022
- 资助金额:
$ 7.28万 - 项目类别:
A Pragmatic Trial of the UCSF Brain Health Assessment for the Detection of Cognitive Impairment in Primary Care
加州大学旧金山分校脑健康评估用于检测初级保健中认知障碍的实用试验
- 批准号:
10524698 - 财政年份:2022
- 资助金额:
$ 7.28万 - 项目类别:
A Pragmatic Trial of the UCSF Brain Health Assessment for the Detection of Cognitive Impairment in Primary Care
加州大学旧金山分校脑健康评估用于检测初级保健中认知障碍的实用试验
- 批准号:
10705314 - 财政年份:2022
- 资助金额:
$ 7.28万 - 项目类别:
PossinK, NIH, R01 Supplement P0568851 4/4/2023
PossinK,NIH,R01 补充 P0568851 4/4/2023
- 批准号:
10820892 - 财政年份:2022
- 资助金额:
$ 7.28万 - 项目类别:
Reimagining Precision Medicine Approaches to AD Diagnosis
重新构想 AD 诊断的精准医学方法
- 批准号:
10604257 - 财政年份:2021
- 资助金额:
$ 7.28万 - 项目类别:
Reimagining Precision Medicine Approaches to AD Diagnosis
重新构想 AD 诊断的精准医学方法
- 批准号:
10382435 - 财政年份:2021
- 资助金额:
$ 7.28万 - 项目类别:
Reimagining Precision Medicine Approaches to AD Diagnosis
重新构想 AD 诊断的精准医学方法
- 批准号:
10211331 - 财政年份:2021
- 资助金额:
$ 7.28万 - 项目类别:
The UCSF Brain Health Assessment for the Detection of Cognitive Impairment Among Diverse Populations in Primary Care
加州大学旧金山分校大脑健康评估,用于检测初级保健中不同人群的认知障碍
- 批准号:
10260511 - 财政年份:2017
- 资助金额:
$ 7.28万 - 项目类别:
The UCSF Brain Health Assessment for the Detection of Cognitive Impairment Among Diverse Populations in Primary Care
加州大学旧金山分校大脑健康评估,用于检测初级保健中不同人群的认知障碍
- 批准号:
9766416 - 财政年份:2017
- 资助金额:
$ 7.28万 - 项目类别:
相似海外基金
Hormone therapy, age of menopause, previous parity, and APOE genotype affect cognition in aging humans.
激素治疗、绝经年龄、既往产次和 APOE 基因型会影响老年人的认知。
- 批准号:
495182 - 财政年份:2023
- 资助金额:
$ 7.28万 - 项目类别:
Parkinson's disease and aging affect neural activation during continuous gait alterations to the split-belt treadmill: An [18F] FDG PET Study.
帕金森病和衰老会影响分体带跑步机连续步态改变期间的神经激活:[18F] FDG PET 研究。
- 批准号:
400097 - 财政年份:2019
- 资助金额:
$ 7.28万 - 项目类别:
The elucidation of the mechanism by which intestinal epithelial cells affect impaired glucose tolerance during aging
阐明衰老过程中肠上皮细胞影响糖耐量受损的机制
- 批准号:
19K09017 - 财政年份:2019
- 资助金额:
$ 7.28万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Does aging of osteocytes adversely affect bone metabolism?
骨细胞老化会对骨代谢产生不利影响吗?
- 批准号:
18K09531 - 财政年份:2018
- 资助金额:
$ 7.28万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Links between affect, executive function, and prefrontal structure in aging: A longitudinal analysis
衰老过程中情感、执行功能和前额叶结构之间的联系:纵向分析
- 批准号:
9766994 - 财政年份:2018
- 资助金额:
$ 7.28万 - 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
- 批准号:
10166936 - 财政年份:2017
- 资助金额:
$ 7.28万 - 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
- 批准号:
9320090 - 财政年份:2017
- 资助金额:
$ 7.28万 - 项目类别:
Affect regulation and Beta Amyloid: Maturational Factors in Aging and Age-Related Pathology
影响调节和 β 淀粉样蛋白:衰老和年龄相关病理学中的成熟因素
- 批准号:
9761593 - 财政年份:2017
- 资助金额:
$ 7.28万 - 项目类别:
Experimental Model of Depression in Aging: Insomnia, Inflammation, and Affect Mechanisms
衰老过程中抑郁症的实验模型:失眠、炎症和影响机制
- 批准号:
9925164 - 财政年份:2016
- 资助金额:
$ 7.28万 - 项目类别:
Experimental Model of Depression in Aging: Insomnia, Inflammation, and Affect Mechanisms
衰老过程中抑郁症的实验模型:失眠、炎症和影响机制
- 批准号:
9345997 - 财政年份:2016
- 资助金额:
$ 7.28万 - 项目类别: