Expanding Opportunities in Genomic Research for Underrepresented Students

摘要：该建议旨在更新基因组学研究(OGR)计划中的机会。自.以来 2007年，圣华盛顿大学麦克唐纳基因组研究所的OGR计划已经用完 并由NHGRI的多样性行动计划提供资金。OGR计划的使命是增加 来自代表不足的群体的学生在基因组科学或基因组科学相关博士学位中的代表性 以及医学博士学位课程。我们寻求通过有效的执行和发展完成我们的使命 为来自种族和种族的学生提供的夏季本科和学年学士学位后研究计划 在科学界代表性不足的种族背景，来自弱势背景的学生，以及 残障人士。这两个OGR项目都为学员提供了基因组科学方面的前沿研究经验 或相关领域和其他11项教育活动，旨在训练他们批判性思维、写作和 有效地谈论他们的研究。工作坊和课程是为培养学生的核心概念而量身定做的 基因组科学、生物信息学和科学报告。职业发展活动的重点是 帮助学生为研究生院面试和研究生院本身做好准备并取得优异成绩。 在其三个资助周期中，OGR项目的学生成果显示出巨大的势头。博士 我们暑期班的学生录取率从第一个周期的29%上升到后两个周期的50%或以上 循环。更令人印象深刻的是，我们学士学位后项目的博士研究生入学人数从#年的44%上升到 第一周期降至第二周期的75%，当前周期的90%。我们期望实施新的 并修改活动，以巩固和扩大这些成果。具体地说，新的活动将促进一体化 在NHGRI T32博士基因组科学计划的OGR学员和学员中，加强以下培训 生物信息学，为受训人员提供更多接触博士可用研究职业多样性的机会 并向服务不足的地区高中及其学生发起社区外展活动。 基于我们计划过去的成功和目前的计划，我们寻求支持再资助五年，以 继续我们的使命，在全国范围内加强博士项目的多样性。我们建议扩大我们的职位- 文凭计划，每年5名实习生，并在大学的支持下，保持我们暑期的规模 本科课程，每个暑期有八名学生。我们相信我们的计划将继续帮助实现 美国多样化的人口中蕴含着巨大的科学和智力潜力，其中大部分 它目前潜伏着，因为我们国家的许多部门在 一般的科学研究，特别是基因组科学。

Abstract: This proposal seeks the renewal of the Opportunities in Genomics Research (OGR) Program. Since 2007, the OGR Program has been run out of The McDonnell Genome Institute at Washington University in Saint Louis and funded through the NHGRI's Diversity Action Plan. The mission of the OGR Program is to increase the representation of students from underrepresented groups in genome science or genome science-related PhD and MD/PhD programs. We seek to accomplish our mission through the effective execution and evolution of summer undergraduate and academic year post-baccalaureate research programs for students from racial and ethnic backgrounds underrepresented in the sciences, students from disadvantaged backgrounds, and students with disabilities. Both OGR programs provide trainees with cutting-edge research experiences in genome science or related fields and 11 other educational activities that seek to train them to think critically and to write and speak effectively about their research. Workshops and classes are tailored to train students in the core concepts of genome science, bioinformatics, and scientific presentation. Professional development activities focus on helping students prepare for and excel in graduate school interviews and graduate school itself. Over its three funding cycles, student outcomes for the OGR program reveal great momentum. PhD matriculation of students in our summer program rose from 29% in the first cycle to 50% or above the last two cycles. More impressively, PhD matriculation of students in our post-baccalaureate program rose from 44% in the first cycle to 75% in the second cycle and 90% in the current cycle. We expect the implementation of new and modified activities to solidify and extend these gains. Specifically, new activities will promote integration among OGR trainees and trainees in the NHGRI T32 PhD Genomic Sciences program, enhance training in bioinformatics, provide trainees with greater exposure to the diversity of research careers available to PhD scientists, and initiate community outreach events to under-served area high schools and their students. Based on the past success and current plans of our program, we seek support for five more years of funding to continue our mission of enhancing diversity in PhD programs nation-wide. We propose to expand our post- baccalaureate program to five trainees per year, and with university support, to maintain the size of our summer undergraduate program at eight students per summer. We believe our programs will continue to help realize the great scientific and intellectual potential inherent within the diverse population of the United States, much of which currently lies latent due to the underrepresentation of many sectors of our nation's population within scientific research in general and genome science in particular.