UNC post-doctoral training program in comparative effectiveness research

描述(由申请人提供)：北卡罗来纳大学教堂山分校(UNC)塞西尔·G·谢普斯中心很高兴提交这份申请，以启动T-32比较有效性研究(CER)博士后培训计划。这一额外的计划将建立在谢普斯中心和AHRQ在卫生服务研究的博士后和博士后培训方面20多年的合作基础上。该计划将由蒂姆·凯里博士指导，他是当前计划和谢普斯中心的主任。CER是一项日益增长的跨学科活动，涉及临床医学、流行病学、卫生政策和药剂学等学科。我们的社会迫切需要评估诊断检测和治疗的最佳战略，以便改善我国公民的保健。CER的组成部分包括：通过系统审查对现有证据进行评价；药物流行病学和模拟研究等观察性研究和分析；进行大规模有效性试验；以及传播和实施活动。我们的13名核心教员来自四所健康科学学院(医学、公共卫生、牙科和药学)和七个系。国家资源中心目前在环境研究中心开展了大量活动，包括通过循证实践网络与AHRQ签订系统审查的总任务订单合同；通过DECLDE网络进行观察性研究；广泛的基于实践的研究网络活动，包括与AHRQ签订的总任务订单合同；大型随机试验；以及传播研究。北卡罗来纳大学也是NIH CTSA网站。预计研究员将参与正在进行的内容和方法研究。授课工作将包括通过北卡罗来纳大学为临床医生提供的公共卫生硕士或硕士学位授予计划。博士生将报名参加侧重于CER方法的精选课程，以及校园内的其他课程。研究人员将参加每周一次的综合研讨会，以及每周一次的关于CER方法的研讨会。我们正在申请资金支持五位研究员，每位为期两年，其中两位从第一年开始，三位从第二年开始。我们还获得了四个外部网站的同意，这些网站的研究与UNCCH相辅相成：消费者联盟、达特茅斯卫生政策研究所、达勒姆VA HSR&D中心和美国放射成像研究网络(ACRIN)。 相关性：LOM、联邦协调委员会、ARRA立法和拟议的医疗改革立法最近的倡议大大增加了比较有效性研究活动的数量及其潜在的政策影响。因此，国家正经历着对更多研究人员的巨大需求，以满足在系统审查、观察性研究、有效性试验和研究传播方面的需求。能够迅速应用的技能尤其重要，一个相关的重点是加强比较有效性研究所涉及的方法。

DESCRIPTION (provided by the applicant): The Cecil G Sheps Center at the University of North Carolina at Chapel Hill (UNC) is pleased to submit this application to initiate a T-32 postdoctoral training program in comparative effectiveness research (CER). This additional program will build on over 20 years of collaboration between the Sheps Center and AHRQ in pre- and postdoctoral training in health services research. The program will be directed by Dr. Tim Carey, director of the current program and of the Sheps Center. CER is a growing interdisciplinary activity, drawing from the disciplines of clinical medicine, epidemiology, health policy, and pharmacy. Our society has an urgent need to evaluate the best strategies of diagnostic testing and treatment so as to improve health care for our citizens. The components of CER include evaluation of current evidence through systematic reviews; observational studies and analyses such as pharmacoepidemiology and modeling research; conduct of large effectiveness trials; and dissemination and implementation activities. Our 13 core faculty are drawn from four health science schools (medicine, public health, dentistry, and pharmacy) and seven departments. UNC has substantial current activities in CER, including master task order contracts with AHRQ for systematic reviews through the Evidence-based Practice (EPC) network; observational studies through the DEclDE network; extensive practice-based research network (PBRN) activities including a master task-order contract with AHRQ; large randomized trials; and dissemination research. UNC is also an NIH CTSA site. Fellows will be expected to participate in ongoing content and methods research. Didactic work will include degree granting programs through UNC-CH's MPH or MS program for clinicians. PhDs will enroll in selected courses focusing on CER methods, as well as elsewhere on campus. Fellows will participate in a weekly integrative seminar, as well as a weekly seminar on CER methods. We are requesting funds to support five fellows for two years each, two to begin in Year 1 and three to begin in Year 2. We have also obtained agreement from four external sites with research complementary to UNCCH: Consumer's Union; the Dartmouth Institute for Health Policy; the Durham VA HSR&D Center; and the American College of Radiology Imaging Research Network (ACRIN). RELEVANCE: Recent initiatives by the lOM, the Federal Coordinating Council, ARRA legislation, and proposed health reform legislation have substantially increased the amount of comparative effectiveness research activity and its potential policy impact. As a result, the nation is experiencing a great need for more researchers to meet the demand in areas of systematic review, observational studies, effectiveness trials, and research dissemination. Skills that can be rapidly applied are especially important, and a related focus is enhancement of the methods involved in comparative effectiveness research.