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PHI-0241- A PHASE I/II CLINICAL TRIAL OF PS-341, A PROTEASOME INHIBITOR, IN C

PHI-0241- A PHASE I/II CLINICAL TRIAL OF PS-341, A PROTEASOME INHIBITOR, IN C
PHI-0241-蛋白酶体抑制剂 PS-341 的 I/II 期临床试验
批准号：
7731382
负责人：
Jeffrey A Sosman
金额：
$0.04万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2006
资助国家：
美国
项目状态：
已结题
起止时间：
2006-12-01 至 2007-09-16
来源：
https://reporter.nih.gov/project-details/7731382
关键词：
ClinicalClinical TrialsComputer Retrieval of Information on Scientific Projects DatabaseDoseFundingGrantInstitutionMaximum Tolerated DosePS341 cpdPhasePhase I Clinical TrialsProteasome InhibitorResearchResearch PersonnelResourcesSourceUnited States National Institutes of Healthbasetemozolomide

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中文摘要
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英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Specific aims: define the optimal doses of temozolomide in combination with PS-341 based upon the optimal biologic dose and the maximum tolerated dose. describe any clinical antitumor activity observed in the Phase I trial.
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Pathway-guided treatment of immune checkpoint inhibitor therapy-induced colon toxicity
(IND 102,133) Inhibition of Aurora Kinase A as Treatment For Melanoma
  • 批准号：
    8142146
  • 项目类别：
  • 资助金额：
    $40.0万
  • 财政年份：
    2010
  • 负责人：
    Jeffrey A Sosman
  • 依托单位：
    VANDERBILT UNIVERSITY
(IND 102,133) Inhibition of Aurora Kinase A as Treatment For Melanoma
  • 批准号：
    7771855
  • 项目类别：
  • 资助金额：
    $40.0万
  • 财政年份：
    2010
  • 负责人：
    Jeffrey A Sosman
  • 依托单位：
    VANDERBILT UNIVERSITY
PHI-0241- A PHASE I/II CLINICAL TRIAL OF PS-341, A PROTEASOME INHIBITOR, IN C
  • 批准号：
    7605557
  • 项目类别：
  • 资助金额：
    $0.8万
  • 财政年份：
    2006
  • 负责人：
    Jeffrey A Sosman
  • 依托单位：
    VANDERBILT UNIVERSITY
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