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Administrative Core

行政核心

基本信息

批准号：
10247785
负责人：
Wendy Demark-Wahnefried
金额：
$ 19.14万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10247785
关键词：
Accelerometer Achievement Adverse event Advocate Aging Amendment Behavior Therapy Behavioral Behavioral Model Biological Markers Body Water Body Weight Body Weight decreased Cancer Survivor Cellular Phone Certification Clinical Trials Data Monitoring Committees Collaborations Collection Communication Computers Cost Analysis Data Data Pooling Databases Devices Diet Dimensions Dissemination and Implementation Doctor of Philosophy Effectiveness Ensure Exercise Foundations Goals Grant Health Health Care Costs Health Food Health behavior Health behavior change Incentives Inflammation Infrastructure Institutional Review Boards Interferon Type II Interleukin-6 Internet Intervention Lead Leadership Link Measures Modeling Monitor Outcome Oxidative Stress Participant Patients Personal Satisfaction Physical Function Physical Performance Physical activity Population Process Progress Reports Protocols documentation Quality Control Quality of life Quality-Adjusted Life Years Reporting Research Research Activity Research Infrastructure Research Personnel Research Project Grants Resource Sharing Resources Rural Minority Services Shipping Ships Specialist Structure Sum Survivors Tablet Computer Technology Telomerase Training Training Support Treatment Efficacy Triage Weight maintenance regimen Work behavior change cancer type cost cost effective cost effectiveness driving behavior efficacious intervention efficacy testing experience human subject immunological status implementation science improved lean body mass meetings multidisciplinary programs secondary analysis social cognitive theory survivorship synergism theories underserved minority

项目摘要

The primary objective of the Administrative (Admin) Shared Resource Core (SRC) is to provide the foundation for integration, coordination, and management of all components of AMPLIFI, (i.e., the three research projects and three additional SRCs). The Admin SRC also is responsible for all budgetary and regulatory activities (processing incentives, IRB clearance and amendments, coordinating DSMB oversight, etc.) and work required for all program components. In addition, the Admin SRC team will arrange for meetings amongst the investigators, and perform the majority of supply shipment, as well as file progress reports. As part of the supplies, the Admin SRC will provide computer tablets and internet service coverage to any study participants who do have current internet access via computers, smartphones or other devices; the IT specialist within this SRC also will provide training and guidance for participants who require this support in order to participate fully in the 3 projects. This SRC also will maintain the study toll-free number and will track, triage, and report any adverse events, and also will coordinate annual DSMB reviews. The Specific Aims are to: (1) Integrate overarching program aims with project-specific outcomes; (2) Coordinate the activities of the research projects and resource cores to ensure that the AMPLIFI goals and outcomes are achieved; and (3) Lead effective management and scientific integration of AMPLIFI components. Using a comprehensive approach, we will leverage our shared resource cores and infrastructure to accomplish the following: 1) identify how best to reach underserved older, rural, and minority cancer survivors; 2) engage survivors in exercising more and making healthier food choices that result in improved diet quality and weight control; 3) determine whether behavioral interventions in specific domains should be presented sequentially or simultaneously in this population; and assess the cost-effectiveness of the adapted health behavior interventions. Thus, the proposed work is integrated and synergistic across multiple dimensions to leverage research infrastructure, collaborative relationships, and the investigators' expertise to achieve greater outcomes compared to the sum of the differential parts.

管理（Admin）共享资源核心（SRC）的主要目标是提供基础