Core: Biorepository and Clinical Trial Office Shared Resource

核心：生物样本库和临床试验办公室共享资源

• 批准号: 10246909
• 负责人: STEVEN L. CARROLL
• 金额: $ 3.12万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-21 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10246909
• 关键词: Academic Medical Centers; Address; African; Biological; Blood; Breast Cancer Patient; Cancer Center; Caring; Clinical; Clinical Research; Clinical Trials; Communities; Data; Development; Enrollment; Faculty; Funding; Future; Goals; Health Services Research; Infrastructure; Leadership; Malignant Neoplasms; Malignant neoplasm of prostate; Medical center; Minority; Morbidity - disease rate; Outcome; Patients; Population Heterogeneity; Provider; Quality of life; Research; Research Personnel; Research Project Grants; Resource Sharing; South Carolina; Specimen; Survivors; Tissues; Universities; anticancer research; base; biobank; cancer care; cancer health disparity; care delivery; clinical center; clinical trial implementation; community setting; ethnic diversity; implementation facilitation; improved; mortality; patient oriented; patient population; racial and ethnic; racial diversity; racial minority; research study; rural area

BIOREPOSITORY AND CLINICAL TRIALS OFFICE SHARED RESOURCE SUMMARY The establishment and implementation of the South Carolina Cancer Disparities Research Center (SC CADRE) Biorepository/Clinical Trials Office (CTO) Shared Resource is expected to significantly expand the research capacity of the SC CADRE investigators at South Carolina State University (SCSU), thus enhancing their ability to compete for independent, R01-level funding. This new, dual-component Shared Resource will also augment SCSU's ability to attract additional junior faculty researchers who will have access to biospecimens from racially and ethnically diverse patient populations as well as to clinical trials infrastructure at the Regional Medical Center of Orangeburg Mabry Cancer Center (RMC-MCC). The overarching goal of the Biorepository/CTO Shared Resource is to support the development of cancer research at SCSU through both a Biorepository component and a CTO component. The Biorepository component will give SC CADRE investigators access to the RMC-MCC's patient blood and tissue specimens that were previously unavailable for research due to the lack of a biorepository infrastructure. Likewise, the CTO component will facilitate the implementation of clinical trials, providing an infrastructure for SCSU investigators to conduct research in their Orangeburg, SC community as well as providing the Orangeburg community immediate access to other NCI- approved clinical trials which have not been available to date. This Shared Resource will support the implementation of two initial SC CADRE clinical trials in Years 1-3 which will provide the biological and outcomes data needed to evaluate the hypothesized relationships that are being assessed in each of the three initial SC CADRE Full and Pilot Research Projects. Additionally, this Biorepository/CTO Shared Resource will support future SC CADRE Full and Pilot Research Projects as well as other NCI-approved clinical research studies at the RMC-MCC, with the goal of enhancing participation of diverse populations in cancer clinical research.

生物储存库和临床试验办公室共享资源 总结 南卡罗来纳州癌症差异研究中心（SC）的建立和实施 CADRE）生物储存库/临床试验办公室（CTO）共享资源预计将显著扩大 南卡罗来纳州州立大学（SCSU）的SC CADRE研究人员的研究能力，从而提高 他们竞争独立的R 01级资金的能力。这种新的双组分共享资源将 也增强SCSU的能力，以吸引更多的初级教师研究人员谁将有机会获得 来自不同种族和民族患者人群的生物样本以及临床试验基础设施， 奥兰治堡马布里癌症中心（RMC-MCC）的区域医疗中心。的首要目标 生物储存库/CTO共享资源将通过以下两种方式支持SCSU癌症研究的发展： 生物储存器组件和CTO组件。生物库组件将为SC CADRE提供 研究人员可以获得以前无法获得的RMC-MCC患者血液和组织标本 由于缺乏生物储存库基础设施，同样，首席技术官部分将促进 实施临床试验，为SCSU研究人员提供基础设施，以便在他们的研究中进行研究。 奥兰治堡，南卡罗来纳州社区，以及提供奥兰治堡社区直接访问其他NCI- 迄今为止尚未获得批准的临床试验。此共享资源将支持 在第1-3年实施两项初始SC CADRE临床试验， 结果数据需要评估假设的关系，正在评估的三个 最初的SC CADRE全面和试点研究项目。此外，该生物储存库/CTO共享资源将 支持未来的SC CADRE完整和试点研究项目以及其他NCI批准的临床研究 RMC-MCC的研究，目的是提高不同人群参与癌症临床研究 research.