Core 1: Biostatistics Core

核心1：生物统计学核心

• 批准号: 10246364
• 负责人: Robert B. Scharpf
• 金额: $ 8.95万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-28 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10246364
• 关键词: Address; Appointment; Area; Authorship; Bioinformatics; Biological Assay; Biological Markers; Biometry; Biostatistics Core; Cancer Center; Classification; Clinic; Clinical; Clinical Research; Clinical Trials Design; Collaborations; Communication; Communities; Complex; Computer software; Consult; Consultations; Data; Data Analyses; Data Analytics; Data Collection; Data Storage and Retrieval; Databases; Development; Disease Progression; Ensure; Environment; Equipment; Experimental Designs; Faculty; Fertilization; Future; Genetic; Genomics; Goals; Group Meetings; Informatics; Joints; Laboratories; Laboratory Study; Longitudinal Studies; Malignant neoplasm of gastrointestinal tract; Manuscripts; Mentors; Methodology; Mutation; Oncology; Positioning Attribute; Procedures; Publications; Reporting; Research; Research Design; Research Personnel; Resources; Risk; Specialist; Statistical Data Interpretation; Techniques; Translating; Translational Research; Translations; Writing; anticancer research; base; clinical investigation; cost effective; data management; data visualization; design; early phase clinical trial; experience; experimental analysis; gastrointestinal; genetic epidemiology; high throughput analysis; member; novel; response; skills; success; sugar; translational study

PROJECT SUMMARY The goal of the GastroIntestinal Biostatistics and Bioinformatics Core (GI-BBC) is to provide wide-ranging, high-quality statistical and bioinformatics support to the GI SPORE. The primary aim of the GI-BBC is to assist GI SPORE investigators in the design, conduct and analysis of laboratory and clinical studies proposed in this SPORE application. The GI-BBC will focus its efforts on assisting both the clinical and laboratory investigators in translating their pre-clinic studies into clinical studies by providing state- of-the-art experimental designs and analyses through statistical consultation and in collaboration with respect to methodology, feasibility, analysis, and reporting of clinical and laboratory studies. In addition, the GI-BBC will serve as an ongoing resource for all GI-SPORE investigators. The Core will be led by Dr. Sugar and Dr. Scharpf and Dr. Rachel Karchin will act as a co-investigator. These GI-BBC faculty members have complementary areas of expertise: Dr. Sugar in biostatistics specializing in translation and clinical study design and analysis, Dr. Scharpf in the analysis of high-throughput genomic assays, Dr. Karchin in computational genetics. Ms. Amanda Blackford, a biostatistician in the Cancer Center, will assist Drs. Sugar and Scharpf in statistical analyses. David McKean, a Master's level bioinformatics specialist will assist Dr. Scharpf. Centralization of statistical needs within the GI-BBC core will provide SPORE investigators with open access to a team of statisticians with the skill set necessary to meet the current and future goals of the SPORE in a cost-effective manner. In addition, it will facilitate communication across SPORE projects, aiding the translation of research findings into the clinical setting.

项目总结