Text2QuitPLUS: A Text-based Smoking Cessation Intervention for Sexual and Gender Minority Groups

摘要 性和性别少数群体（SGM）吸烟，其中包括女同性恋，男同性恋，双性恋和 据不同来源的报道，跨性别（LGBT）个体的患病率很高（男同性恋者为46 女同性恋者占48%）。考虑到SGM组的吸烟率是SGM组的两倍多， 一般人群（19%）和吸烟占所有癌症死亡的至少30%，很明显， SGM个体患这种致命疾病的风险增加。短信程序已经被 发现对戒烟和其他健康行为有效。他们呼吁传统的硬- 接触到的、有戒烟干预障碍的高危人群，以及 移动的电话和短信的使用率，这是SGM用户的情况。Text 2 Quit是一种吸烟 戒烟干预，根据自己选择的戒烟日期向用户发送量身定制的支持性文本。 尽管该计划已在一项随机试验中成功地对普通人群进行了评估， 也适合孕妇，但没有研究评估其在SGM中的可行性 吸烟者。我提出了3个具体目标：（1）开发和评估Text 2 QuitPLUS的设计，一个SGM定制的 版本的Text 2 Quit，通过定性方法在16名SGM成年吸烟者中进行;（2）检查招募， 在80名随机分组的SGM吸烟者中，随访1个月、3个月和6个月时的戒烟率 原始的Text 2 Quit或Text 2 QuitPLUS程序武装。参与这些方案也将是 通过计算系统中每位SGM参与者的短信回复数量来衡量 （3）对32名完成吸烟者吸烟记录的吸烟者进行混合方法研究。 可行性试验，以更好地了解研究参与者对戒烟干预的接受程度。结果将 有助于减少SGM群体之间与烟草有关的健康差距。艾琳·塔米-莫里医学博士理学硕士， P.H.博士一位拉丁裔科学家被任命为研究助理教授（非终身教职）在大学 德克萨斯州医学博士安德森，正在寻求通过NCI K22过渡职业发展奖3年的支持 促进多样性，为拟议的过渡职业发展计划和研究。为了填补关键的 在她的经验的差距，她将获得专门的培训，专家的意见，和第一手经验， 实施针对服务不足人群的行为干预措施，移动健康和先进的统计数据， 分析纵向数据。她还将扩大她的知识和技能有关的戒烟，SGM 健康差异和研究伦理。Tami-Maury博士的全面培训和研究计划， 由该领域的知名研究人员组成的咨询委员会，将确保她的长期目标， 一个独立资助的癌症预防和戒烟研究项目，重点是减少 SGM个体与烟草相关的健康差异。

ABSTRACT Smoking among sexual and gender minority (SGM) groups, which include lesbian, gay, bisexual, and transgender (LGBT) individuals, has been reported from different sources as highly prevalent (46% for gay men and 48% for lesbians). Considering that the smoking rate within SGM groups is more than double that of the general population (19%) and that smoking accounts for at least 30% of all cancer deaths, it is clear that there is an increased risk for SGM individuals to suffer from this fatal condition. Text messaging programs have been found to be effective for smoking cessation and other health behaviors. They are appealing to traditionally hard- to-reach, at-risk populations who experience barriers to smoking cessation interventions, and who have high rates of mobile phone and text messaging use, which is the case for SGM users. Text2Quit is a smoking cessation intervention that sends tailored, supportive texts to users based on self-selected smoking quit date. Although this program has been successfully evaluated with the general population in a randomized trial and has been also tailored to pregnant women, no study has evaluated its feasibility specifically among SGM smokers. I propose 3 specific aims: (1) To develop and evaluate the design of Text2QuitPLUS, an SGM-tailored version of Text2Quit, through a qualitative approach among 16 SGM adult smokers; (2) To examine recruitment, retention, and smoking abstinence rates at 1, 3, and 6 months of follow-up among 80 SGM smokers randomized to either the original Text2Quit or Text2QuitPLUS program arms. Engagement with the programs will be also measured by calculating the number of text message responses for each SGM participant from the system records; (3) To conduct mixed-method research among 32 SGM smokers completing their participation in the feasibility trial to better understand study participants' acceptability of the cessation interventions. Results will contribute to reducing tobacco-related health disparities among SGM groups. Irene Tami-Maury, D.M.D., M.Sc., Dr.P.H., a Latina scientist appointed as a Research Assistant Professor (non-tenure track) at The University of Texas MD Anderson, is seeking 3 years of support through an NCI K22 Transition Career Development Award to Promote Diversity for the proposed transition career development plan and research. In order to fill critical gaps in her experience, she will obtain specialized training, expert advice, and first-hand experience in implementing behavioral interventions targeting underserved populations, mHealth, and advanced statistics for analyzing longitudinal data. She will also expand her knowledge and skills related to tobacco cessation, SGM health disparities, and research ethics. Dr. Tami-Maury's comprehensive training and research plans, supported by an advisory committee of established researchers in the field, will secure her long-term goal of establishing anindependently funded research program in cancer prevention and tobacco cessation, with a focus on reducing tobacco-related health disparities for SGM individuals.