Text2QuitPLUS: A Text-based Smoking Cessation Intervention for Sexual and Gender Minority Groups

摘要 在性和性别少数群体(SGM)中吸烟，包括女同性恋、男同性恋、双性恋和 变性人(LGBT)，已从不同来源报告为高度流行(46%的男同性恋者 女同性恋者为48%)。考虑到SGM组的吸烟率是SGM的两倍多 普通人群(19%)，吸烟至少占所有癌症死亡的30%，显然有 SGM患者罹患这种致命疾病的风险增加。短信程序已经被 被发现对戒烟和其他健康行为有效。他们正在呼吁传统上强硬的- 可触及的高危人群，他们在戒烟干预方面遇到障碍，而且 手机和短信使用率，这是SGM用户的情况。文本2戒烟是一种吸烟 戒烟干预，根据自己选择的戒烟日期向用户发送量身定制的支持性短信。 尽管这项计划已经在随机试验中成功地在普通人群中进行了评估， 也是为孕妇量身定做的，还没有研究专门评估它在SGM中的可行性 吸烟者。我提出了三个具体目标：(1)开发和评估为SGM量身定做的Text2QuitPLUS的设计 Text2戒烟版本，通过对16名SGM成年吸烟者进行定性研究；(2)审查招募情况， 随机抽取的80名SGM吸烟者在1、3和6个月的随访中保持吸烟率和戒烟率 到原始的Text2Quit或Text2QuitPLUS程序ARM。与项目的接触也将是 通过计算来自系统的每个SGM参与者的文本消息回复数来衡量 记录；(3)对32名SGM吸烟者进行混合方法研究，完成他们在 可行性试验，以更好地了解研究参与者对戒烟干预的可接受性。结果将 有助于减少特殊转基因群体中与烟草有关的健康差距。艾琳·塔米-莫里，医学博士，理科硕士， P.H.博士，一位拉丁裔科学家，被任命为加州大学研究助理教授(非终身教职) 德克萨斯州MD安德森正在通过NCI K22过渡职业发展奖寻求3年的支持 以促进多样性为建议的过渡职业发展计划和研究。为了填补关键的 在她的经验差距中，她将获得专门的培训、专家建议和第一手经验 实施针对服务不足人群的行为干预、mHealth和高级统计数据 分析纵向数据。她还将扩大她在戒烟方面的知识和技能 健康差距和研究道德。Tami-Maury博士的全面培训和研究计划，得到支持 由该领域的知名研究人员组成的咨询委员会，将确保她建立 一个独立资助的癌症预防和戒烟研究计划，重点是减少 SGM个人与烟草相关的健康差距。

ABSTRACT Smoking among sexual and gender minority (SGM) groups, which include lesbian, gay, bisexual, and transgender (LGBT) individuals, has been reported from different sources as highly prevalent (46% for gay men and 48% for lesbians). Considering that the smoking rate within SGM groups is more than double that of the general population (19%) and that smoking accounts for at least 30% of all cancer deaths, it is clear that there is an increased risk for SGM individuals to suffer from this fatal condition. Text messaging programs have been found to be effective for smoking cessation and other health behaviors. They are appealing to traditionally hard- to-reach, at-risk populations who experience barriers to smoking cessation interventions, and who have high rates of mobile phone and text messaging use, which is the case for SGM users. Text2Quit is a smoking cessation intervention that sends tailored, supportive texts to users based on self-selected smoking quit date. Although this program has been successfully evaluated with the general population in a randomized trial and has been also tailored to pregnant women, no study has evaluated its feasibility specifically among SGM smokers. I propose 3 specific aims: (1) To develop and evaluate the design of Text2QuitPLUS, an SGM-tailored version of Text2Quit, through a qualitative approach among 16 SGM adult smokers; (2) To examine recruitment, retention, and smoking abstinence rates at 1, 3, and 6 months of follow-up among 80 SGM smokers randomized to either the original Text2Quit or Text2QuitPLUS program arms. Engagement with the programs will be also measured by calculating the number of text message responses for each SGM participant from the system records; (3) To conduct mixed-method research among 32 SGM smokers completing their participation in the feasibility trial to better understand study participants' acceptability of the cessation interventions. Results will contribute to reducing tobacco-related health disparities among SGM groups. Irene Tami-Maury, D.M.D., M.Sc., Dr.P.H., a Latina scientist appointed as a Research Assistant Professor (non-tenure track) at The University of Texas MD Anderson, is seeking 3 years of support through an NCI K22 Transition Career Development Award to Promote Diversity for the proposed transition career development plan and research. In order to fill critical gaps in her experience, she will obtain specialized training, expert advice, and first-hand experience in implementing behavioral interventions targeting underserved populations, mHealth, and advanced statistics for analyzing longitudinal data. She will also expand her knowledge and skills related to tobacco cessation, SGM health disparities, and research ethics. Dr. Tami-Maury's comprehensive training and research plans, supported by an advisory committee of established researchers in the field, will secure her long-term goal of establishing anindependently funded research program in cancer prevention and tobacco cessation, with a focus on reducing tobacco-related health disparities for SGM individuals.