Text2QuitPLUS: A Text-based Smoking Cessation Intervention for Sexual and Gender Minority Groups

Text2QuitPLUS：针对性少数群体的基于文本的戒烟干预措施

• 批准号: 10251013
• 负责人: Irene Tami-Maury
• 金额: $ 15.77万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10251013
• 关键词: Abstinence; Adult; Advisory Committees; Back; Behavior Therapy; California; Car Phone; Career Mobility; Censuses; Cessation of life; Computers; Conscious; Control Groups; Cotinine; Data; Data Analyses; Development Plans; Discrimination; Doctor of Medicine; Enrollment; Environment; Event; Festival; Focus Groups; Funding; Future; Gays; Gender Identity; General Population; Goals; Health behavior; Heterosexuals; High Prevalence; Homophobia; Individual; Intervention; Knowledge; Latina; Lesbian; Lesbian Gay Bisexual Transgender; Mainstreaming; Malignant Neoplasms; Measures; Methods; Minority Groups; New York; Participant; Patient Self-Report; Population; Populations at Risk; Pregnant Women; Randomized; Randomized Controlled Trials; Records; Reporting; Research; Research Assistant; Research Design; Research Ethics; Research Methodology; Research Personnel; Risk; Saliva; Sampling; Scientist; Secure; Sex Orientation; Sexual and Gender Minorities; Smoker; Smoking; Smoking Cessation Intervention; Source; Stigmatization; Stress; Surveys; System; Telephone; Test Result; Testing; Texas; Text; Text Messaging; Tobacco; Tobacco Use Cessation; Tobacco use; Training; Transition Career Development Award (K22); Underserved Population; United States; Universities; Vulnerable Populations; Work; anticancer research; arm; base; brief advice; cancer prevention; cancer risk; career; cigarette smoke; cigarette smoking; coping; design; digital; experience; feasibility trial; follow-up; group intervention; health disparity; longitudinal analysis; mHealth; men; minority communities; nicotine replacement; professor; programs; psychosocial stressors; randomized trial; recruit; research and development; response; retention rate; same-sex partnership; skills; smoking abstinence; smoking cessation; social stigma; statistics; text messaging intervention; tobacco advertising; two-arm trial

ABSTRACT Smoking among sexual and gender minority (SGM) groups, which include lesbian, gay, bisexual, and transgender (LGBT) individuals, has been reported from different sources as highly prevalent (46% for gay men and 48% for lesbians). Considering that the smoking rate within SGM groups is more than double that of the general population (19%) and that smoking accounts for at least 30% of all cancer deaths, it is clear that there is an increased risk for SGM individuals to suffer from this fatal condition. Text messaging programs have been found to be effective for smoking cessation and other health behaviors. They are appealing to traditionally hard- to-reach, at-risk populations who experience barriers to smoking cessation interventions, and who have high rates of mobile phone and text messaging use, which is the case for SGM users. Text2Quit is a smoking cessation intervention that sends tailored, supportive texts to users based on self-selected smoking quit date. Although this program has been successfully evaluated with the general population in a randomized trial and has been also tailored to pregnant women, no study has evaluated its feasibility specifically among SGM smokers. I propose 3 specific aims: (1) To develop and evaluate the design of Text2QuitPLUS, an SGM-tailored version of Text2Quit, through a qualitative approach among 16 SGM adult smokers; (2) To examine recruitment, retention, and smoking abstinence rates at 1, 3, and 6 months of follow-up among 80 SGM smokers randomized to either the original Text2Quit or Text2QuitPLUS program arms. Engagement with the programs will be also measured by calculating the number of text message responses for each SGM participant from the system records; (3) To conduct mixed-method research among 32 SGM smokers completing their participation in the feasibility trial to better understand study participants' acceptability of the cessation interventions. Results will contribute to reducing tobacco-related health disparities among SGM groups. Irene Tami-Maury, D.M.D., M.Sc., Dr.P.H., a Latina scientist appointed as a Research Assistant Professor (non-tenure track) at The University of Texas MD Anderson, is seeking 3 years of support through an NCI K22 Transition Career Development Award to Promote Diversity for the proposed transition career development plan and research. In order to fill critical gaps in her experience, she will obtain specialized training, expert advice, and first-hand experience in implementing behavioral interventions targeting underserved populations, mHealth, and advanced statistics for analyzing longitudinal data. She will also expand her knowledge and skills related to tobacco cessation, SGM health disparities, and research ethics. Dr. Tami-Maury's comprehensive training and research plans, supported by an advisory committee of established researchers in the field, will secure her long-term goal of establishing anindependently funded research program in cancer prevention and tobacco cessation, with a focus on reducing tobacco-related health disparities for SGM individuals.

抽象的 性少数群体（SGM）中的吸烟情况，包括女同性恋、男同性恋、双性恋和 据不同来源报道，变性人 (LGBT) 非常普遍（男同性恋者占 46% 女同性恋者为 48%）。考虑到SGM群体内的吸烟率是普通群体的两倍多 普通人群 (19%) 以及吸烟造成的癌症死亡人数至少占所有癌症死亡人数的 30%，很明显， SGM 个人患这种致命疾病的风险增加。短信程序已 发现对戒烟和其他健康行为有效。他们正在吸引传统上硬 接触到在戒烟干预方面遇到障碍且吸烟率较高的高危人群 手机和短信的使用率，SGM 用户的情况就是如此。 Text2Quit 是吸烟 戒烟干预，根据用户自行选择的戒烟日期向用户发送定制的支持性文本。 尽管该计划已在一项随机试验中成功地对普通人群进行了评估，并且 也为孕妇量身定制，但没有研究专门评估其在 SGM 中的可行性 吸烟者。我提出了3个具体目标：（1）开发和评估Text2QuitPLUS的设计，这是一个SGM定制的 Text2Quit 版本，通过对 16 名 SGM 成年吸烟者进行定性研究； （二）审查招聘情况， 80 名随机 SGM 吸烟者在随访 1、3 和 6 个月时的保留率和戒烟率 到原始 Text2Quit 或 Text2QuitPLUS 程序臂。参与该计划也将 通过计算系统中每位 SGM 参与者的短信回复数量来衡量 记录； (3) 对完成参与调查的32名SGM吸烟者进行混合方法研究 可行性试验，以更好地了解研究参与者对戒烟干预措施的接受程度。结果将 有助于减少 SGM 团体之间与烟草相关的健康差异。艾琳·塔米-莫里 (Irene Tami-Maury)，医学博士、理学硕士， Dr.P.H.，一位拉丁裔科学家，被任命为英国大学研究助理教授（非终身教授） 德克萨斯州 MD 安德森正在通过 NCI K22 过渡职业发展奖寻求 3 年支持 为促进多元化提出过渡职业发展计划和研究。为了填补关键 她将获得专业培训、专家建议和第一手经验 针对服务不足的人群、移动医疗和先进的统计数据实施行为干预 分析纵向数据。她还将拓展与戒烟、SGM相关的知识和技能 健康差异和研究道德。 Tami-Maury 博士的综合培训和研究计划得到支持 由该领域知名研究人员组成的咨询委员会将确保她的长期目标 一项独立资助的癌症预防和戒烟研究计划，重点是减少 SGM 个人与烟草相关的健康差异。