Modular Adaptive Virtual Reality Intervention for Clinical Substance use disorder (MAVRICS)

临床药物使用障碍的模块化自适应虚拟现实干预 (MAVRICS)

• 批准号: 10256275
• 负责人: Michelle (Micki) E Washburn
• 金额: $ 25.66万
• 依托单位: INNATEVR, LLC
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10256275
• 关键词: Acute; Address; Algorithms; Ambulatory Care; Area; Behavior Therapy; Behavioral; Benchmarking; Child Welfare; Chronic; Client; Clinical; Clinical Trials; Complex; Computer software; Cues; Custom; Development; Digital Libraries; Disease; Emergency Care; Environment; Epidemic; Exposure to; Feedback; Financial Hardship; Focus Groups; Goals; HIV Infections; HIV/HCV; Health Personnel; Helping to End Addiction Long-term; Immersion; Impairment; Individual; Intervention; Justice; Left; Measurable; Mental Health; Methods; Mission; National Institute of Drug Abuse; Neonatal Abstinence Syndrome; Opioid; Outpatients; Phase; Probability; Public Health; Recovery; Relapse; Research; Residential Treatment; Risk; Small Business Technology Transfer Research; Social Interaction; Software Tools; Standardization; Strategic Planning; Substance Use Disorder; Supervision; Supportive care; System; Technology; Testing; Time; Translating; Update; base; behavioral health; community burden; cost; craving; design; disorder later incidence prevention; disorder prevention; effectiveness evaluation; expectation; experience; improved; mortality; new technology; novel; opioid misuse; opioid overdose; opioid use; opioid use disorder; physical conditioning; premature; prescription opioid misuse; programs; relapse risk; social; standardize measure; substance abuse treatment; substance misuse; substance use; usability; virtual; virtual environment; virtual reality; virtual reality intervention

PROJECT SUMMARY/ABSTRACT Opioid Use Disorder (OUD) is a chronic, recurring condition that if left untreated, poses a significant and ongoing public health threat. OUD is associated with significant impairments in physical and psychological health including increased mortality and high utilization of emergency medical care as well as increased risk of Hepatitis C and HIV infection and Neonatal Abstinence Syndrome (NAS). OUD is also associated with increased justice and child welfare systems involvement. Currently, the number of empirically supported behavioral interventions for the treatment of OUDs is limited, the majority of which cannot be tailored (customized) to meet the unique needs of the individual client. As such, the relapse rate for individuals with OUDs remains high. Virtual reality cue exposure (VRCE) has shown considerable promise in addressing substance craving, one of the most salient components of OUD. Through repeated exposure to substance use cues within a controlled virtual environment, over time these virtual exposures weaken the relationship between substance use cues and craving, potentially leading to decreased substance use and lower probability of substance relapse. Unfortunately, currently available commercial VR products lack the essential ability to easily and repeatedly update exposure environments to introduce novelty or incorporate new or evolving substance use cues. This limitation results in less user engagement over time, potentially leading to user disengagement and premature treatment termination. This research aims to improve upon currently available commercial virtual reality (VR) products designed to address substance misuse by developing a novel subscription-based software product (Helix) that supports ongoing customization of virtual reality-based cue exposure (VRCE) environments resulting in a tailored intervention addressing substance craving. Using measurable benchmarks on standardized assessments of usability and acceptability and informed by feedback from focus groups of key stakeholders, the Helix software will continually be refined until satisfactory levels of usability and acceptability are achieved. This software will also be evaluated to determine if it is feasible for use in both residential and outpatient substance abuse treatment settings.

项目总结/文摘