Wadsworth Center's Radiochemical, Microbiological and Chemical Testing for Food Defense and Capability Development

项目摘要 （总体）： 该提案的首要目标是充分利用沃兹沃斯中心可观的实验室能力 作为世界级公共卫生实验室和研究机构的能力，加上其科学专长， 创建一流的综合性食品放射化学、微生物和化学检测计划 防御和能力发展，将服务于FDA食品应急响应的未来需求 Network（FERN）.在其目前作为FDA-FERN合作协议实验室的成功基础上， 食品的α、β和γ放射性监测;作为FDA食品安全和 应用营养学（CFSAN）合作协议GenomeTrakr实验室;并作为美国农业部食品安全 美国食品安全检验局（FSIS）微生物和化学食品防御合作协议实验室 沃兹沃斯中心将提供关键的领导，科学专业知识和分析支持，以弗恩根据 实验室灵活资助模式（LFFM）。从微生物学，生物防御，放射化学和 从核计数技术到化学试验， 最先进的质谱仪，沃兹沃斯往往是最后的实验室，纽约州政府机构 求助于。该提案的范围包括：微生物学食品防御; 沃兹沃斯中心的核心测序设施，并将序列和元数据上传到GenomeTrakr NCBI的伞式项目;新鲜样品中环孢子虫的分子检测方法开发 使用实时PCR进行生产[4];化学食品有机和无机毒素防御;放射性 筛选和量化食品中的砷和镉排放物;以及制定砷的检测方法 LC-ICP-MS法测定海产品中形态

PROJECT SUMMARY (Overall): The overarching goal of this proposal is to leverage the Wadsworth Center’s considerable laboratory capabilities and capacity as a world-class public health laboratory and research institute, coupled with its scientific expertise to create a first-class integrated Radiochemical, Microbiological and Chemical Testing Program for Food Defense and Capability Development that will serve the future needs of the FDA’s Food Emergency Response Network (FERN). Building on its current success as an FDA-FERN Cooperative Agreement laboratory for the Surveillance of Foods for Alpha, Beta, and Gamma Radioactivity; as an FDA Center for Food Safety and Applied Nutrition (CFSAN) Cooperative Agreement GenomeTrakr laboratory; and as a USDA Food Safety Inspection Service (FSIS) Cooperative Agreement laboratory for Microbiology and Chemistry Food Defense, the Wadsworth Center will provide key leadership, scientific expertise and analytical support to FERN under the proposed Laboratory Flexible Funding Model (LFFM). From microbiology, biodefense, radiochemistry and nuclear counting technologies, to chemical testing for emergency response and preparedness based on state of the art mass spectrometry, Wadsworth is often the laboratory of last resort that NY state government agencies turn to for help. The scope of this proposal includes: Microbiology Food Defense; Sequencing of isolates in the Wadsworth Center’s core sequencing facility, and the sequence and metadata uploaded to the GenomeTrakr umbrella project at NCBI; method development for molecular detection of Cyclospora cayetanensis in fresh produce using Real-Time PCR [4]; Chemistry Food Defense for organic and inorganic toxins; Radiological screening and quantification for  , and  emitters in food products; and development of a method for arsenic speciation in seafood by LC-ICP-MS.