Wadsworth Center's Radiochemical, Microbiological and Chemical Testing for Food Defense and Capability Development

项目总结 (整体)： 这项提议的首要目标是利用沃兹沃斯中心可观的实验室能力 和作为世界级公共卫生实验室和研究机构的能力，加上其科学专长 创建一流的食品放射化学、微生物和化学综合检测方案 国防和能力发展，将服务于FDA未来的食品紧急反应需求 网络(蕨类)。在其目前作为FDA-Fern合作协议实验室的成功基础上 食品中α、β和伽马放射性的监测；作为FDA食品安全和食品安全中心 应用营养学(CFSAN)合作协议GenomeTrakr实验室；并作为美国农业部食品安全 食品防务检验局微生物和化学合作协议实验室 沃兹沃斯中心将为弗恩提供关键的领导、科学专业知识和分析支持 建议的实验室灵活资助模式(LFFM)。从微生物学、生物防御、放射化学和 核计数技术，到基于状态的应急反应和准备的化学试验 作为艺术质谱学，沃兹沃斯经常是纽约州政府机构最后的实验室 寻求帮助。这项建议的范围包括：微生物食品防御；在食品中分离的菌株的测序 沃兹沃斯中心的核心测序设施，以及上传到GenomeTrakr的序列和元数据 NCBI伞形项目；新鲜卡耶坦环孢菌分子检测方法的发展 使用实时荧光聚合酶链式反应[4]生产；有机和无机毒素的化学食品防护；放射性 食品中和排放物的筛选和定量；砷的检测方法的建立 LC-ICP-MS法测定海产品中的形态

PROJECT SUMMARY (Overall): The overarching goal of this proposal is to leverage the Wadsworth Center’s considerable laboratory capabilities and capacity as a world-class public health laboratory and research institute, coupled with its scientific expertise to create a first-class integrated Radiochemical, Microbiological and Chemical Testing Program for Food Defense and Capability Development that will serve the future needs of the FDA’s Food Emergency Response Network (FERN). Building on its current success as an FDA-FERN Cooperative Agreement laboratory for the Surveillance of Foods for Alpha, Beta, and Gamma Radioactivity; as an FDA Center for Food Safety and Applied Nutrition (CFSAN) Cooperative Agreement GenomeTrakr laboratory; and as a USDA Food Safety Inspection Service (FSIS) Cooperative Agreement laboratory for Microbiology and Chemistry Food Defense, the Wadsworth Center will provide key leadership, scientific expertise and analytical support to FERN under the proposed Laboratory Flexible Funding Model (LFFM). From microbiology, biodefense, radiochemistry and nuclear counting technologies, to chemical testing for emergency response and preparedness based on state of the art mass spectrometry, Wadsworth is often the laboratory of last resort that NY state government agencies turn to for help. The scope of this proposal includes: Microbiology Food Defense; Sequencing of isolates in the Wadsworth Center’s core sequencing facility, and the sequence and metadata uploaded to the GenomeTrakr umbrella project at NCBI; method development for molecular detection of Cyclospora cayetanensis in fresh produce using Real-Time PCR [4]; Chemistry Food Defense for organic and inorganic toxins; Radiological screening and quantification for  , and  emitters in food products; and development of a method for arsenic speciation in seafood by LC-ICP-MS.