Prevention of Substance Use in At-risk Students: A Family-centered Web Program

项目总结 注射毒品(PWID)的人是社会弱势群体，并暴露在风险因素中，包括 不稳定的住房和潜在的医疗条件，如人类免疫缺陷病毒(HIV)， 结核病和病毒性肝炎，使他们面临更高的严重新冠肺炎症状的风险，包括 死亡。残疾人也面临障碍，例如医疗保健的污名化和歧视的历史。 系统和暴露在有关检测的错误信息中，减少了获得保健服务和检测的机会。 因为及时接受与症状出现相关的服务对于积极的健康结果和 减少SARS-CoV-2传播，缺乏检测对PWID有重大影响，凸显迫在眉睫 需要在这一人群中增加测试的接受度。尽管如此，PWID一直没有得到足够的服务 在当前大流行的背景下；因此，人们对新冠肺炎和 残疾人对新冠肺炎检测的可接受性和可能覆盖范围。为了解决这一差距，这项研究 利用目前与俄勒冈州艾滋病联盟(HIVA)的合作伙伴关系以及我们的社区和科学咨询 董事会支持新冠肺炎测试计划的实施和可持续性。具体地说，我们将使用 基于社区的参与式方法来开发、实施和评估新冠肺炎测试项目 通过Hiva的注射器服务计划(SSP)提供，这是PWID的自然护理点。此外，SSP 一旦可用，可为疫苗的传播和交付提供一个自然的场所。新冠肺炎的试水 该计划将包括样本采集程序，将样本传输到俄勒冈大学 CLIA认证的实验室和结果报告。对于目标1，我们将评估测试程序的利用率。为 目标2，我们将开发和测试一个简短的动机增强干预措施，以优化测试利用率 在PWID中。使用中断时间序列设计，我们将评估干预对资源利用的影响 新冠肺炎测试资源。对于目标3，我们将从注射器交换人员和主要志愿者那里收集数据 计划的可接受性、可行性、适当性、采用率、实施障碍和促进者 与测试计划和干预相关。当前的项目具有提升新冠肺炎的潜力 在服务严重不足的人群中测试访问和覆盖范围，这些人群面临多种风险 使预防SARS-CoV-2接触和传播变得困难，并增加了患严重肺炎的风险 新冠肺炎的症状，如果他们感染了这种疾病。

PROJECT SUMMARY People who inject drugs (PWIDs) are a socially vulnerable population and are exposed to risk factors including unstable housing and underlying medical conditions such as human immunodeficiency virus (HIV), tuberculosis (TB), and viral hepatitis that put them at increased risk for severe COVID-19 symptoms, including death. PWIDs also experience barriers such as a history of stigmatization and discrimination by health care systems and exposure to misinformation about testing that reduces access to health care services and testing. Because timely receipt of services relative to symptoms onset is critical for positive health outcomes and to reduce SARS-CoV-2 transmission, lack of testing has significant implications for PWID, highlighting an urgent need to increase testing uptake among this population. Despite this, PWIDs have been an underserved population in the context of the current pandemic; thus, little is known about the prevalence of COVID-19 and the acceptability and possible reach of testing for COVID-19 among PWIDs. To address this gap, this study leverages a current partnership with HIV Alliance (HIVA) in Oregon and our Community and Scientific Advisory Board to support implementation and sustainability of a COVID-19 testing program. Specifically, we will use community-based participatory approaches to develop, implement, and evaluate a COVID-19 testing program offered through HIVA’s Syringe Services Programs (SSP), a natural point of care for PWIDs. Moreover, SSPs may offer a natural venue for dissemination and delivery of a vaccine, once available. The COVID-19 testing program will include procedures for sample collection, transmission of specimens to the University of Oregon CLIA-certified laboratory, and results reporting. For aim 1, we will assess the testing program utilization. For aim 2, we will develop and test a brief motivational enhancement intervention to optimize testing utilization among PWIDs. Using an interrupted time series design, we will evaluate intervention effects on utilization of COVID-19 testing resources. For aim 3, we will collect data from syringe exchange staff and key volunteers on program acceptability, feasibility, appropriateness, adoption, and implementation barriers and facilitators related to the testing program and intervention. The current project has the potential to enhance COVID-19 testing access and reach among a significantly underserved population who experience multiple risks that make it difficult to prevent SARS-CoV-2 exposure and transmission and who are at increased risk for severe COVID-19 symptoms, if they were to contract the disease.