Prevention of Substance Use in At-risk Students: A Family-centered Web Program

预防高危学生的药物使用：以家庭为中心的网络计划

• 批准号: 10258908
• 负责人: ELIZABETH A STORMSHAK
• 金额: $ 121.32万
• 依托单位: UNIVERSITY OF OREGON
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2022-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10258908
• 关键词: 2019-nCoV; AIDS/HIV problem; Address; Adopted; Adoption; American; CLIA certified; COVID-19; COVID-19 testing; COVID-19 vaccine; Centers for Disease Control and Prevention (U.S.); Cessation of life; Client; Communities; Contracts; County; Data; Data Collection; Diagnostic tests; Discrimination; Disease; Equipment and Supplies; Exposure to; Family; General Population; Goals; HIV; HIV Infections; HIV/HCV; Health; Healthcare Systems; Hospitals; Hygiene; Immunocompromised Host; Individual; Infrastructure; Injecting drug user; Internet; Interruption; Intervention; Laboratories; Laboratory Personnel; Leadership; Link; Medical; Misinformation; Molecular; Motivation; Needle-Exchange Programs; Oregon; Outcome; Pilot Projects; Population; Prevalence; Preventive; Procedures; Process; Program Acceptability; Protocols documentation; Public Health; Quarantine; RADx Underserved Populations; Recording of previous events; Reporting; Research; Resources; Risk; Risk Factors; SARS-CoV-2 exposure; SARS-CoV-2 transmission; Series; Services; Social Network; Source; Specimen; Stigmatization; Students; Symptoms; System; Testing; Time; Trust; Tuberculosis; Underserved Population; Universities; Vaccination; Vaccines; Viral hepatitis; Virus; Vulnerable Populations; base; checkup examination; design; experience; follow-up; health care availability; health care service; housing instability; implementation barriers; implementation facilitators; implementation framework; implementation outcomes; intervention effect; laboratory experience; motivational enhancement therapy; pandemic disease; point of care; prevent; programs; sample collection; scale up; service delivery; service utilization; severe COVID-19; social health determinants; social vulnerability; substance use prevention; testing access; testing services; testing uptake; transmission process; volunteer

PROJECT SUMMARY People who inject drugs (PWIDs) are a socially vulnerable population and are exposed to risk factors including unstable housing and underlying medical conditions such as human immunodeficiency virus (HIV), tuberculosis (TB), and viral hepatitis that put them at increased risk for severe COVID-19 symptoms, including death. PWIDs also experience barriers such as a history of stigmatization and discrimination by health care systems and exposure to misinformation about testing that reduces access to health care services and testing. Because timely receipt of services relative to symptoms onset is critical for positive health outcomes and to reduce SARS-CoV-2 transmission, lack of testing has significant implications for PWID, highlighting an urgent need to increase testing uptake among this population. Despite this, PWIDs have been an underserved population in the context of the current pandemic; thus, little is known about the prevalence of COVID-19 and the acceptability and possible reach of testing for COVID-19 among PWIDs. To address this gap, this study leverages a current partnership with HIV Alliance (HIVA) in Oregon and our Community and Scientific Advisory Board to support implementation and sustainability of a COVID-19 testing program. Specifically, we will use community-based participatory approaches to develop, implement, and evaluate a COVID-19 testing program offered through HIVA’s Syringe Services Programs (SSP), a natural point of care for PWIDs. Moreover, SSPs may offer a natural venue for dissemination and delivery of a vaccine, once available. The COVID-19 testing program will include procedures for sample collection, transmission of specimens to the University of Oregon CLIA-certified laboratory, and results reporting. For aim 1, we will assess the testing program utilization. For aim 2, we will develop and test a brief motivational enhancement intervention to optimize testing utilization among PWIDs. Using an interrupted time series design, we will evaluate intervention effects on utilization of COVID-19 testing resources. For aim 3, we will collect data from syringe exchange staff and key volunteers on program acceptability, feasibility, appropriateness, adoption, and implementation barriers and facilitators related to the testing program and intervention. The current project has the potential to enhance COVID-19 testing access and reach among a significantly underserved population who experience multiple risks that make it difficult to prevent SARS-CoV-2 exposure and transmission and who are at increased risk for severe COVID-19 symptoms, if they were to contract the disease.

项目摘要 注射毒品者是社会弱势群体，面临的风险因素包括 不稳定的住房和潜在的医疗条件，如人体免疫缺陷病毒（艾滋病毒）， 肺结核（TB）和病毒性肝炎，使他们患严重COVID-19症状的风险增加，包括 死亡残疾人还遇到障碍，如卫生保健方面的污名化和歧视历史 系统和暴露于有关测试的错误信息，减少了获得医疗保健服务和测试。 因为及时接受与症状发作相关的服务对于积极的健康结果至关重要， 减少SARS-CoV-2传播，缺乏测试对PWID有重大影响，强调迫切需要 需要在这一人群中增加检测。尽管如此，PWID一直是服务不足的 在当前大流行的背景下，人口数量减少;因此，对COVID-19的流行情况知之甚少， 在PWID中进行COVID-19检测的可接受性和可能范围。为了弥补这一差距，本研究 利用与俄勒冈州的艾滋病联盟（HIVA）以及我们的社区和科学咨询机构的现有合作关系 董事会支持COVID-19测试计划的实施和可持续性。具体来说，我们将使用 以社区为基础的参与式方法，以制定、实施和评估COVID-19检测计划 通过HIVA的注射器服务计划（SSP）提供，这是PWID的自然护理点。此外，SSP 一旦有了疫苗，就可以为疫苗的传播和运送提供一个自然的场所。COVID-19检测 该计划将包括样本收集程序，标本传输到俄勒冈州大学 CLIA认证的实验室和结果报告。对于目标1，我们将评估测试程序的利用率。为 目标2，我们将开发和测试一个简短的动机增强干预，以优化测试利用率 在PWID中。使用中断的时间序列设计，我们将评估干预对药物利用的影响。 COVID-19检测资源。对于目标3，我们将从注射器交换工作人员和主要志愿者那里收集数据， 计划的可接受性、可行性、适当性、采用和实施的障碍和促进因素 与测试程序和干预有关。目前的项目有可能提高COVID-19 测试服务严重不足的人群的获取和覆盖情况，这些人群面临多种风险， 这使得难以预防SARS-CoV-2暴露和传播， COVID-19症状，如果他们感染了这种疾病。