A wearable high-density MEG system with uOPMs

摘要 在这个二期项目中，我们将使用我们的 微OPM传感器，并与当前基于Squid的MEG系统交叉验证我们的系统。一个 整个系统包括(1)传感器系统--由128个传感器及其控制电子设备组成的阵列 其执行同步数据采集和控制；(2)符合脑磁图形状的脑磁图 头和保持传感器阵列；(3)集成传感器扫描系统，以定位位置和 每个传感器相对于磁头的方向；(4)集成的有源线圈系统，以补偿 在记录期间使用来自传感器阵列的反馈的背景场梯度；以及(5)用户 接口软件无缝地控制和收集来自所有子系统的信号和元数据。这个 系统将交付给我们在费城儿童医院(CHOP)的合作者进行交叉- 在成人和儿童中针对当前的鱿鱼MEG系统进行验证。我们还将评估其 当前技术无法实现的范式性能，这可能会将服务开放给 患者群体目前被拒绝，并扩大了此类系统的应用范围。

Abstract In this Phase II project, we will build a complete high-density wearable full-head MEG system using our micro-OPM sensors and to cross-validate our system against current SQUID-based MEG systems. A complete system consists of (1) the sensor system - an array of 128 sensors and their control electronics that performs synchronous data collection and control; (2) a MEG cap that conforms to the shape of the head and holds the sensor array; (3) an integrated sensor scanning system to localize the position and orientation of each sensor relative to the head; (4) an integrated active coil system to compensate for the background field gradients using feedback from the sensor array during recording; and (5) a user interface software seamlessly controls and collects signals and metadata from all the sub-systems. The system will be delivered to our collaborators at the Children’s Hospital of Philadelphia (CHOP) for cross- validation against the current SQUID MEG system in adults and children. We will also evaluate its performance in paradigms that are impossible with current technology, which could open services to patient groups currently denied, and broaden the range of applications for such systems.