Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity

虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动

基本信息

  • 批准号:
    10267739
  • 负责人:
  • 金额:
    $ 83.78万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2019
  • 资助国家:
    美国
  • 起止时间:
    2019-09-25 至 2024-07-31
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY Chronic low back pain (cLBP) is a prevalent and costly condition that markedly impairs physical, emotional, and social function. Despite its overwhelming burden of illness, with one in four adults reporting frequent back pain, available drug therapies are limited in their ability to provide lasting benefits and improve health-related quality of life (HRQOL). Patients with cLBP frequently turn to opioids when other pharmacotherapies fail to provide adequate analgesia, yet often discover that opioids also fall short in delivering meaningful pain reduction or improving HRQOL. Hence, there is a critical gap in pain management in cLBP; it is vital to address this evidence gap in a way that maximizes benefits for patients while minimizing harms from medical therapy. Therapeutic virtual reality (VR) has emerged as a promising and evidence-based treatment modality for musculoskeletal pain, including cLBP. Users of VR wear a pair of goggles with a close-proximity stereoscopic screen that creates a sensation of being transported into lifelike, three-dimensional worlds. By stimulating the visual cortex while engaging other senses, VR modulates the user’s processing of nociceptive stimuli. Functional magnetic resonance imaging (fMRI) of the brain reveals that VR has similar effects on the sensory and insular cortex as opioids, and head-to-head trials show that VR achieves similar or greater analgesia as hydromorphone. However, there are few data regarding long-term efficacy and safety of VR in cLBP. To date, VR has been limited to short-term clinical trials. In addition, limited research exists on VR modalities beyond mere distraction, such as VR therapy that teaches exportable skills using cognitive behavioral therapy (CBT), guided meditation, and biofeedback-based breathing exercises. To address these gaps, we propose to measure patient-reported outcomes (PROs), biometric outcomes, and opioid use in 360 nonspecific cLBP patients randomized among 3 groups and followed for 90 days: (1) immersive skills-based VR therapy; (2) immersive distraction VR therapy; and (3) non-immersive sham VR using 2D videos displayed in a VR headset. The results will inform best practices for implementing VR in cLBP and identify patient-level predictors of efficacy.
项目总结

项目成果

期刊论文数量(0)
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Brennan Spiegel其他文献

Brennan Spiegel的其他文献

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{{ truncateString('Brennan Spiegel', 18)}}的其他基金

Transcending COVID-19 barriers to pain care in rural America: Pragmatic comparative effectiveness trial of evidence-based, on-demand, digital behavioral treatments for chronic pain
超越美国农村地区疼痛护理的 COVID-19 障碍:针对慢性疼痛的循证、按需、数字行为治疗的实用比较有效性试验
  • 批准号:
    10425444
  • 财政年份:
    2021
  • 资助金额:
    $ 83.78万
  • 项目类别:
Transcending COVID-19 barriers to pain care in rural America: Pragmatic comparative effectiveness trial of evidence-based, on-demand, digital behavioral treatments for chronic pain
超越美国农村地区疼痛护理的 COVID-19 障碍:针对慢性疼痛的循证、按需、数字行为治疗的实用比较有效性试验
  • 批准号:
    10610907
  • 财政年份:
    2021
  • 资助金额:
    $ 83.78万
  • 项目类别:
Transcending COVID-19 barriers to pain care in rural America: Pragmatic comparative effectiveness trial of evidence-based, on-demand, digital behavioral treatments for chronic pain
超越美国农村地区疼痛护理的 COVID-19 障碍:针对慢性疼痛的循证、按需、数字行为治疗的实用比较有效性试验
  • 批准号:
    10242572
  • 财政年份:
    2021
  • 资助金额:
    $ 83.78万
  • 项目类别:
Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity
虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动
  • 批准号:
    10671360
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:
Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity
虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动
  • 批准号:
    10683125
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:
Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity
虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动
  • 批准号:
    10896861
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:
Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity (HEAL Supplement)
虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动(HEAL 补充)
  • 批准号:
    10650652
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:
Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity: Understanding Patient Predictors of Response
虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动:了解患者反应的预测因素
  • 批准号:
    10350470
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:
Randomized-controlled trial of virtual reality for chronic low back pain to improve patient-reported outcomes and physical activity
虚拟现实治疗慢性腰痛的随机对照试验,以改善患者报告的结果和身体活动
  • 批准号:
    10472620
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:
Improving representation of non-Hispanic Black and Hispanic study participants in a trial of virtual reality for chronic lower back pain
改善慢性腰痛虚拟现实试验中非西班牙裔黑人和西班牙裔研究参与者的代表性
  • 批准号:
    10400468
  • 财政年份:
    2019
  • 资助金额:
    $ 83.78万
  • 项目类别:

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