Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network

ECHO IDeA 州儿科临床试验网络数据协调和运营中心

• 批准号: 10240720
• 负责人: Jeannette Y. Lee
• 金额: $ 787.91万
• 依托单位: UNIV OF ARKANSAS FOR MED SCIS
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-23 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10240720
• 关键词: Address; Affect; Age; Airway Disease; Area; Arkansas; Award; Biomedical Research; Biometry; Biostatistics Core; Caring; Centers of Research Excellence; Child; Child Care; Child Health; Childhood; Clinical; Clinical Investigator; Clinical Research; Clinical Sciences; Clinical Trials; Clinical Trials Cooperative Group; Clinical Trials Network; Clinical and Translational Science Awards; Conduct Clinical Trials; Data; Data Coordinating Center; Development; Diagnosis; Disease; Dissemination and Implementation; Doctor of Philosophy; Eligibility Determination; Environment; Functional disorder; Funding; Future; Grant; Health; Informatics; Infrastructure; Leadership; Logistics; Medical; Medicine; Mentors; Methodology; Multi-Institutional Clinical Trial; Multicenter Studies; Nebraska; Obesity; Outcome; Patients; Pediatric Research; Physicians; Pilot Projects; Population; Population Distributions; Population Heterogeneity; Prevention; Principal Investigator; Publishing; Randomized Controlled Trials; Recording of previous events; Reporting; Research; Research Activity; Research Institute; Research Personnel; Research Project Grants; Rural; Science; Scientist; Site; Training and Education; Translational Research; United States National Institutes of Health; Universities; Work; base; college; community engagement; data management; design; drug metabolism; evidence base; experience; improved; interest; medically underserved; medically underserved population; member; neurodevelopment; operation; pediatric department; pediatric patients; programs; research and development; rural area; rural underserved; skill acquisition

PROJECT SUMMARY Eligibility for the Institutional Development Award (IDeA) program is based on historically low levels of NIH funding. IDeA states differ from non-IDeA states with respect to the rural/urban distributions of the population and access to medical care. Compared to children in non-IDeA states, children in IDeA states are more likely to live in rural areas and are less likely to have access to or receive medical care. Since multi-center pediatric clinical trial networks are concentrated in centers in non-IDeA states, there are limited opportunities for children living in IDeA states to participate in clinical research activities. The ECHO IDeA States Clinical Trials Network (ISPCTN) was established in 2016 with 17 clinical awardee sites and the Data Coordinating and Operations Center (DCOC) at the University of Arkansas for Medical Sciences (UAMS) in Little Rock, Arkansas. The objectives of the Network are to develop and implement clinical research in the IDeA states in the ECHO priority areas: upper and lower airway disease; obesity; neurodevelopment; pre-, peri-, and post-natal outcomes; and positive child health; and to develop capacity within the IDeA states to conduct clinical trial research. This proposal is for UAMS to continue to serve as the DCOC for the ECHO ISPCTN. The specific aims of the Data Coordination and Operations Center are to 1) Provide scientific, operational, administrative and logistical infrastructure support to the ECHO IDeA States Pediatric Clinical Trials Network (ISPCTN) to facilitate the development, implementation and dissemination of clinical research activities in the ISPCTN; and 2) Build pediatric clinical research capacity in the IDeA states to enhance the potential for conducting clinical trials that address health issues of relevance to children in IDeA states. We will work collaboratively with clinical investigators at the ISPCTN sites, Project Scientists and Project Officers at the NIH ECHO Office, and other participating NIH staff, and collaborating multicenter clinical trials groups to design and implement studies that will address health issues that disproportionately affect rural and medically underserved children.

项目摘要 机构发展奖（IDEA）计划的资格是基于NIH的历史低水平 经费在人口的农村/城市分布方面，IDEA州与非IDEA州不同 和获得医疗服务的权利与非IDEA状态的儿童相比，IDEA状态的儿童更有可能 生活在农村地区的妇女更少，更不可能获得或接受医疗保健。由于多中心儿科 临床试验网络集中在非IDEA州的中心，儿童的机会有限 居住在IDEA州参加临床研究活动。 ECHO IDEA国家临床试验网络（ISPCTN）成立于2016年，共有17名临床获奖者 研究中心和阿肯色州医学大学的数据协调和运营中心（DCOC） 位于阿肯色州的小石城。该网络的目标是制定和实施 IDEA的临床研究在ECHO优先领域：上呼吸道和下呼吸道疾病;肥胖; 神经发育;产前、产后和产后结果;积极的儿童健康;以及发展能力 在IDEA州内进行临床试验研究。 本提案要求UAMS继续担任ECHO ISPCTN的DCOC。的具体目标 数据协调和操作中心将 1)为ECHO IDEA提供科学、运营、行政和后勤基础设施支持 美国儿科临床试验网络（ISPCTN），以促进发展，实施和 在ISPCTN中传播临床研究活动;以及 2)在IDEA州建立儿科临床研究能力，以提高开展 临床试验，解决与IDEA州儿童相关的健康问题。 我们将与ISPCTN研究中心的临床研究者、项目科学家和项目 NIH ECHO办公室的官员和其他参与NIH的工作人员，以及合作的多中心临床试验 设计和实施研究，解决不成比例地影响农村和农村地区的健康问题。 医疗服务不足的儿童。