Administrative Core

行政核心

• 批准号: 10252036
• 负责人: ANUPAM AGARWAL
• 金额: $ 16.62万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10252036
• 关键词: Acute Renal Failure with Renal Papillary Necrosis; Address; Administrator; Advisory Committees; Alabama; Area; Biometry; California; Clinical; Clinical Research; Clinical and Translational Science Awards; Collaborations; Communication; Communities; Decision Making; Development; Effectiveness; Electronic Mail; Ensure; Environment; Evaluation; Extramural Activities; Faculty; Feasibility Studies; Fostering; Functional disorder; Funding; Funding Opportunities; Goals; Grant; Individual; Institution; Interdisciplinary Study; Investigation; Investments; Journals; Kidney; Kidney Diseases; Knowledge; Leadership; Methodology; National Institute of Diabetes and Digestive and Kidney Diseases; Newsletter; Online Systems; Pilot Projects; Postdoctoral Fellow; Process; Progress Reports; Publications; Quality Control; Reagent; Recommendation; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Schedule; Series; Services; Site; Structure; Students; Technology; Training; Training Programs; Training and Education; United States National Institutes of Health; Universities; Videoconferencing; Visit; Work; authority; base; career development; catalyst; cost effective; design; experience; innovation; meetings; news; operation; outreach; professor; programs; ranpirnase; summer student; symposium; training opportunity; web site

Project Summary The University of Alabama at Birmingham (UAB)-University of California at San Diego (UCSD) O'Brien Center for Acute Kidney Injury (AKI) is designed to provide scientifically rigorous, state-of-the-art methodologies in a cost-effective manner to foster investigations that will (i) continue to attract new scientific expertise into the study of the basic mechanisms of kidney diseases, specifically AKI; (ii) encourage interdisciplinary research; (iii) explore new basic areas with translational potential; (iv) generate Pilot and Feasibility studies that provide new and innovative approaches to study kidney disease; and (v) apply scientifically rigorous, state-of-the-art methodologies in a cost-effective manner to address experimental questions to advance understanding of the pathophysiology of AKI. The Administrative Core will coordinate and integrate the diverse activities of the UAB- UCSD O'Brien Center, facilitate interactions and collaborations among the research base, ensure quality control, rigor and reproducibility of the core services and promote scientific development. The Administrative Core includes a Biostatistical Resource (BR), which will provide statistical support for the cores and research and pilot projects of the O'Brien Center. The administrative structure with clear lines of authority has been developed to ensure that the goals and objectives of the Center are achieved. The Director and Associate Directors will be advised by an Internal Advisory Committee, who were carefully selected based on their experience in directing high quality large research programs and include the Directors of the Clinical and Translational Science Awards (CTSA) at both UAB and UCSD. In addition, the Center leadership will be advised by an External Advisory Committee, a Pilot and Feasibility (PAF) Program Committee and a Scientific Advisory Committee for each Core. The Administrative Core will continue to oversee the PAF Program and will be responsible for evaluating the Pilot Program's efficacy in promoting high quality AKI-related research that leads to extramural funding and publications. In addition, the Administrative Core will organize and support an Enrichment Program consisting of symposia, seminars with visiting speakers, journal clubs/work-in progress sessions, interface with CTSA enrichment programs, Summer Students Training Program, and an Annual Comprehensive Research Symposium. The Administrative Core has also established a communication network through email, newsletters, live video conferencing and a website to inform Center investigators of the activities and funding opportunities, AKI-related news, as well as the availability of new reagents and technologies through the Center. Therefore, the Administrative Core will enable optimal coordination of the various Center components through its committees, regularly scheduled meetings, seminar series, web-based communication mechanisms and video conferences between participating institutions.

项目摘要 阿拉巴马大学伯明翰（UAB） - 加利福尼亚州圣地亚哥大学（UCSD）奥布莱恩 急性肾脏损伤中心（AKI）旨在提供科学严格的最先进的方法论 以成本效益的方式来促进（i）继续吸引新的科学专业知识的调查 研究肾脏疾病的基本机制，特别是AKI； （ii）鼓励跨学科研究； （iii） 探索具有转化潜力的新基本领域； （iv）生成提供新的飞行员和可行性研究 以及研究肾脏疾病的创新方法； （v）应用科学严格，最先进的 方法论以具有成本效益的方式解决实验问题，以提高对 AKI的病理生理学。行政核心将协调和整合UAB的各种活动 UCSD O'Brien Center，促进研究基础之间的互动和合作，确保质量控制， 核心服务的严格和可重复性并促进科学发展。行政核心 包括生物统计资源（BR），该资源将为核心和研究提供统计支持 奥布莱恩中心的项目。 已经开发了具有明确权力线的行政结构，以确保目标和目标 实现了中心的目标。董事和副董事将由内部建议 咨询委员会，根据他们指导高质量大型的经验而精心挑选的咨询委员会 研究计划，包括临床和转化科学奖（CTSA）的董事 UAB和UCSD。此外，外部咨询委员会将向中心领导 和可行性（PAF）计划委员会和每个核心的科学咨询委员会。 行政核心将继续监督PAF计划，并将负责评估 飞行员计划在促进与AKI相关的高质量研究方面的功效，该研究导致校外资金和 出版物。此外，行政核心将组织和支持由 研讨会，访客演讲者的研讨会，期刊俱乐部/工作进度会议，与CTSA的界面 丰富计划，夏季学生培训计划和年度全面研究 座谈会。行政核心还通过电子邮件，新闻通讯， 实时视频会议和网站，以将中心调查人员告知活动和资金机会， 与AKI相关的新闻，以及通过中心的新试剂和技术的可用性。所以， 行政核心将通过其各种中心组件实现最佳协调 委员会，定期安排的会议，研讨会系列，基于网络的沟通机制和视频 参与机构之间的会议。