A PHASE I DOSE ESCALATION STUDY OF TOPICAL BEXAROTENE IN WOMEN AT HIGH RISK FOR BREAST CANCER

乳腺癌高危女性局部使用贝沙罗汀的 I 期剂量递增研究

• 批准号: 10251826
• 负责人: POWEL BROWN
• 金额: $ 10.61万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2021-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10251826
• 关键词: Bexarotene; Breast; Breast Cancer Risk Factor; Clinical Trials; Dose; Evaluation; Gel; High Risk Woman; Intervention; Mammary Gland Parenchyma; Maximum Tolerated Dose; Phase; Safety; Testing; Toxic effect; Woman

The proposed clinical trial will evaluate safety and toxicity of topical bexarotene 1% gel to the breast in healthy women at high risk for breast cancer and bexarotene concentration in the breast tissue.

拟议的临床试验将评价局部用1%贝沙罗汀凝胶对乳腺癌高危健康女性乳房的安全性和毒性以及乳房组织中的贝沙罗汀浓度。