Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.
Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.
批准号:
488246
负责人:
Muller William J
金额:
$83.04万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-09-01 至 2028-09-01
中文摘要
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英文摘要
Breast cancer remains the second deadliest cancer for Canadian women and its morbidity is largely attributed to relapse in patients from recurrent tumors. Tumors that enter a state of dormancy can eventually reactivate and often confer drug resistance and
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会议论文
Chi3L1 (YKL-40) plays a multifaceted role in modulating tumor immune microenvironment during breast cancer progression.
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批准号:478513
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项目类别:Operating Grants
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资助金额:$93.07万
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财政年份:2023
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负责人:Muller William J
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依托单位:
Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.
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批准号:483129
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资助金额:$7.29万
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依托单位:
Identification of Stat1 signaling pathway(s) involved in mediating tumor escape from immune surveillance.
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The multifaceted role of c-Src tyrosine kinase in breast cancer progression.
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批准号:468470
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资助金额:$83.6万
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财政年份:2022
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负责人:Muller William J
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依托单位:
Chi3L1 (YKL-40) plays a multifaceted role in modulating tumor immune microenvironment during breast cancer progression.
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批准号:472379
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项目类别:Operating Grants
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资助金额:$7.29万
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财政年份:2022
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负责人:Muller William J
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依托单位:
Role of epigenetic modulation in breast cancer etiology and drug resistance.
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批准号:368101
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财政年份:2017
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依托单位:
The role of an alternative ErbB2 splice isoform in lung and breast cancer progression.
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批准号:341907
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资助金额:$59.59万
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财政年份:2016
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负责人:Muller William J
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依托单位:
Development of a pre-clinical mouse model of Estrogen receptor alpha positive breast cancer to investigate the clinical efficacy of Selective Estrogen Receptor Modulators (SERMs)
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批准号:341905
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资助金额:$59.59万
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财政年份:2016
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负责人:Muller William J
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依托单位:
Oncogene-mediated signal transduction in transgenic mouse models of human breast cancer
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批准号:333085
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财政年份:2015
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负责人:Muller William J
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依托单位:
Canada Research Chair Tier 1
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批准号:341360
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项目类别:
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资助金额:$101.99万
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财政年份:2015
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负责人:Muller William J
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依托单位:
Oncogene-mediated signal transduction in ErbB2 transgenic models of mammary tumour progression
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批准号:280158
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项目类别:Operating Grants
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资助金额:$56.09万
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财政年份:2013
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负责人:Muller William J
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依托单位:
Identification of PI-3K coupled signalling pathways involved in mammary tumour progression: Implication for resistance to targeted therapy.
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批准号:291796
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资助金额:$61.28万
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财政年份:2013
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负责人:Muller William J
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依托单位:
Role of epigenetic modulation in breast cancer etiology and drug resistance
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批准号:277365
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财政年份:2012
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负责人:Muller William J
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依托单位:
Integrin-mediated signal transduction in mammary tumourigenesis and metastasis
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批准号:249551
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资助金额:$7.29万
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财政年份:2011
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负责人:Muller William J
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依托单位:
The role of ErbB2-14-3-3 sigma signaling axis in cancer and development
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批准号:199253
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项目类别:Operating Grants
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资助金额:$56.71万
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财政年份:2010
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负责人:Muller William J
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依托单位:
The role of Epidermal Growth Factor Receptor Family in mammary tumorigenesis and metastasis
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批准号:171470
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财政年份:2008
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负责人:Muller William J
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依托单位:
国内基金
海外基金
2C型蛋白磷酸酶REDUCED DORMANCY 5通过激酶-磷酸酶蛋白复合体调控种子休眠的分子机制
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批准号:32000250
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项目类别:青年科学基金项目
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资助金额:24.0万元
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批准年份:2020
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负责人:陈熙
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依托单位: