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Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer

Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer
解读单细胞突变过程对三阴性乳腺癌和高级别浆液性卵巢癌的影响
批准号:
477662
负责人:
Aparicio Samuel J
金额:
$75.79万
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2023
资助国家:
加拿大
项目状态:
未结题
起止时间:
2023-03-01 至 2028-03-01

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中文摘要
翻译
三阴性乳腺癌(TNBC)约占早期乳腺癌的15%,75%的TNBC预后不良。同样值得关注的是,高级别浆液性卵巢癌(HGSOC)是最致命的妇科恶性肿瘤。两种癌症都有进展
英文摘要
Triple negative breast cancer (TNBC) accounts for approximately 15% of early breast cancers, and 75% of TNBCs have poor prognosis. Similarly concerning, high grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy. Both cancers devel
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会议论文
Mechanisms and targeting of repair deficient cancers with G-quadruplex small molecule ligands
  • 批准号:
    478057
  • 项目类别:
    Operating Grants
  • 资助金额:
    $76.35万
  • 财政年份:
    2023
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer.
  • 批准号:
    477245
  • 项目类别:
    Operating Grants
  • 资助金额:
    $7.29万
  • 财政年份:
    2022
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
Canada Research Chair - Tier 1
  • 批准号:
    459667
  • 项目类别:
  • 资助金额:
    $101.99万
  • 财政年份:
    2021
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
Targeting the dynamics and genomics of clonal evolution in cancer patients
  • 批准号:
    333653
  • 项目类别:
    Operating Grants
  • 资助金额:
    $206.42万
  • 财政年份:
    2015
  • 负责人:
    Aparicio Samuel J
  • 依托单位:
海外基金