PPE Request

个人防护装备要求

• 批准号: 10261164
• 负责人: Karen Kesler
• 金额: $ 37.36万
• 依托单位: RHO FEDERAL SYSTEMS DIVISION, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-02-05 至 2022-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10261164
• 关键词: Administrative Supplement; Biological; Blood specimen; Boston; COVID-19; COVID-19 pandemic; COVID-19 patient; Clinical; Clinical Data; Cohort Studies; Data; Data Coordinating Center; Diagnostic radiologic examination; Eye; Face; Funding; Genomics; Grant; Growth; Human; Immune response; Immunophenotyping; Intervention; Laboratories; Masks; National Institute of Allergy and Infectious Disease; Nose; Pediatric Hospitals; Predisposition; Resources; Site; Therapeutic; Therapeutic Intervention; Virus Shedding; cohort; respiratory; vaccine response

PROJECT SUMMARY / ABSTRACT To meet the challenge of the COVID-19 pandemic, Boston Children's Hospital (BCH) requested and received an administrative supplement to NIAID grant U19AI118608 “Ontogeny of Human Vaccine Responses” to fund the Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) Clinical and Data Coordinating Center (CDCC). The IMPACC study is an observational cohort collecting detailed clinical, laboratory, and radiographic data in coordination with biologic sampling of blood and respiratory secretions and viral shedding in nasal secretions in order to identify immunophenotypic and genomic features of COVID-19–related susceptibility and/or progression in order to generate hypotheses for effective host-directed therapeutic interventions, to help to prioritize proposals for such interventions, and/or optimize timing for administration of host-response directed therapeutics. Many sites in the IMPACC study lacked sufficient PPE to protect all study site staff interacting with hospitalized COVID-19 patients. Therefore, the IMPACC CDCC sought additional resources to distribute to the participating sites. RhoFED responded to this need by procuring the necessary additional PPE, which consisted of masks, masks with eye shields, gowns, gloves, and face shields.

项目概要/摘要 为了应对 COVID-19 大流行的挑战，波士顿儿童医院 (BCH) 请求并收到了 NIAID 拨款 U19AI118608“人类疫苗反应的个体发生”的行政补充，以资助 COVID-19 队列 (IMPACC) 临床和数据协调中心的免疫表型评估 （疾病预防控制中心）。 IMPACC 研究是一项观察性队列研究，收集详细的临床、实验室和放射学数据 数据与血液和呼吸道分泌物的生物采样以及鼻腔病毒脱落相配合 分泌物以确定与 COVID-19 相关的易感性的免疫表型和基因组特征 和/或进展，以便产生有效的针对宿主的治疗干预的假设，以帮助 优先考虑此类干预措施的建议，和/或优化东道国响应管理的时间安排 定向治疗。 IMPACC 研究中的许多地点缺乏足够的个人防护装备来保护与住院患者互动的所有研究地点工作人员 COVID-19 患者。因此，IMPACC CDCC 寻求额外的资源来分配给参与方 网站。 RhoFED 通过采购必要的额外个人防护装备来满足这一需求，其中包括口罩、 带眼罩的口罩、长袍、手套和面罩。