PPE Request

项目摘要/摘要 为迎接新冠肺炎疫情的挑战，波士顿儿童医院要求并收到 NIAID拨款U19AI118608“人类疫苗反应的个体发生”的行政补充资金 新冠肺炎队列临床和数据协调中心的免疫表型评估 (CDCC)。IMPACC研究是一项观察性队列研究，收集详细的临床、实验室和放射学资料。 与血液和呼吸道分泌物的生物采样以及鼻腔病毒脱落相结合的数据 分泌物的免疫表型和基因组特征的鉴定新冠肺炎相关的敏感性 和/或进展，以便产生有效的宿主指导的治疗干预的假设，以帮助 确定此类干预建议的优先顺序，和/或优化管理宿主反应的时间 定向治疗学。 IMPACC研究中的许多站点缺乏足够的个人防护设备来保护所有与住院患者互动的研究站点工作人员 新冠肺炎患者。因此，IMPACC CDCC寻求额外资源，以分发给各参与方 网站。RhoFED通过采购必要的额外个人防护设备来回应这一需求，其中包括口罩， 带眼罩、长袍、手套和面罩的口罩。

PROJECT SUMMARY / ABSTRACT To meet the challenge of the COVID-19 pandemic, Boston Children's Hospital (BCH) requested and received an administrative supplement to NIAID grant U19AI118608 “Ontogeny of Human Vaccine Responses” to fund the Immunophenotyping Assessment in a COVID-19 Cohort (IMPACC) Clinical and Data Coordinating Center (CDCC). The IMPACC study is an observational cohort collecting detailed clinical, laboratory, and radiographic data in coordination with biologic sampling of blood and respiratory secretions and viral shedding in nasal secretions in order to identify immunophenotypic and genomic features of COVID-19–related susceptibility and/or progression in order to generate hypotheses for effective host-directed therapeutic interventions, to help to prioritize proposals for such interventions, and/or optimize timing for administration of host-response directed therapeutics. Many sites in the IMPACC study lacked sufficient PPE to protect all study site staff interacting with hospitalized COVID-19 patients. Therefore, the IMPACC CDCC sought additional resources to distribute to the participating sites. RhoFED responded to this need by procuring the necessary additional PPE, which consisted of masks, masks with eye shields, gowns, gloves, and face shields.