Georgia Cystic Fibrosis Research and Translation Core Center

乔治亚州囊性纤维化研究与转化核心中心

• 批准号: 10260484
• 负责人: NAEL A MCCARTY
• 金额: $ 8.71万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-10 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10260484
• 关键词: Adherence; Behavioral; Budgets; Chronic; Collaborations; Communication; Communities; Consultations; Creativeness; Cystic Fibrosis; Disease; Effectiveness; Evaluation; Faculty; Family; Funding; Goals; Growth; Institution; Knowledge; Leadership; Life Style; Link; Liver diseases; Mentors; Metabolism; Mission; Monitor; National Institute of Diabetes and Digestive and Kidney Diseases; Newsletter; Nutritional status; Physicians; Problem Solving; Process; Productivity; Reporting; Research; Research Personnel; Research Support; Resources; Scientist; Services; Shapes; Sleep; Strategic Planning; Systemic disease; Training Activity; Translations; Universities; base; clinical care; cohesion; cystic fibrosis patients; cystic fibrosis related diabetes; diet and exercise; gastrointestinal function; liver function; meetings; member; outreach; program dissemination; programs; ranpirnase; recruit; symposium; translational impact; web site

PROJECT SUMMARY – Administrative Core This application proposes to establish the Georgia Cystic Fibrosis Research and Translation Core Center at Emory University, Augusta University, and Georgia Tech (hereafter referred to as the “Georgia CF Core Center”), which will leverage a wide range of activities at these three institutions to solve problems associated with this chronic, systemic disease. Research supported by the Georgia CF Core Center will focus on aspects of CF disease central to the mission of the NIDDK, including CF-related diabetes (CFRD), the impact of CF on nutritional status, gastrointestinal function, liver function (including CF-related liver disease, CFLD), and metabolism, and the relationship between these complications of CF disease and lifestyle/behavioral choices such as diet, exercise, activity, and sleep. Led by Georgia CF Core Center Director, Dr. Nael McCarty, the Administrative Core serves to tie the three primary institutions together in pursuit of research that results in new knowledge that is impactful upon CF clinical care. The Administrative Core is responsible for the overall leadership, coordination, and management of the Georgia CF Core Center, including facilitating interactions among investigators and Core users, allocation and oversight of resources, and promoting the Center. The Administrative Core also will serve the needs of the Center Members and the CF patient/family community by providing a high quality Enrichment and Dissemination Program that will be extended to all three primary institutions. We will accomplish these goals through the following Specific Aims and activities: Aim 1. Formulate and implement a strategic plan for shaping, expanding, and optimizing CF research at Emory, Georgia Tech, and Augusta University, and other regional institutions. Rationale: A well-thought out and executed strategic plan is crucial for effective promotion and dissemination of CF research. Aim 2. Provide oversight and direction, monitor progress, and promote growth for all CF research programs and Cores. Rationale: Implementing a synergistic, coordinated, and integrated program for advancing CF research requires high-level administrative direction and oversight. The Center’s effectiveness depends on its ability to use resources wisely, meet its goals, and as necessary, adapt Center goals as research questions, challenges, opportunities, and support needs evolve. Aim 3. Promote interactions and communication between Core Center institutions and investigators. Rationale: Enabling interdisciplinary interactions, collaborations, and effective communication promotes cohesion, creativity, and productivity.

项目概要-行政核心 本申请建议在以下地点建立格鲁吉亚囊性纤维化研究和翻译核心中心： 埃默里大学、奥古斯塔大学和格鲁吉亚理工学院（以下简称“格鲁吉亚CF核心 中心”），该中心将利用这三个机构的广泛活动，解决与 这种慢性全身性疾病由格鲁吉亚CF核心中心支持的研究将侧重于以下方面 CF疾病的核心NIDDK的使命，包括CF相关的糖尿病（CFRD），CF对 营养状态、胃肠道功能、肝功能（包括CF相关肝病，CFLD），以及 代谢，以及CF疾病的这些并发症与生活方式/行为选择之间的关系 如饮食、锻炼、活动和睡眠。在格鲁吉亚CF核心中心主任Nael McCarty博士的带领下， 行政核心服务于将三个主要机构联系在一起，以追求产生新成果的研究。 对CF临床护理有影响的知识。行政核心负责全面 领导、协调和管理格鲁吉亚CF核心中心，包括促进互动 在研究者和核心用户之间，分配和监督资源，并促进中心。的 行政核心还将通过以下方式满足中心成员和CF患者/家庭社区的需求 提供一个高质量的丰富和传播方案，将扩大到所有三个主要 机构职能体系我们将通过以下具体目标和活动实现这些目标： 目标1。制定和实施战略计划，以塑造，扩大和优化CF研究， 埃默里大学、格鲁吉亚理工大学、奥古斯塔大学和其他地区性机构。理由：经过深思熟虑 战略计划的制定和实施是有效推广和传播森林资源研究的关键。 目标2.提供监督和指导，监控进度，并促进所有CF研究计划的增长 和核心。理由：实施一个协同、协调和综合的计划，以推进CF 研究需要高级别的行政指导和监督。中心的有效性取决于 它有能力明智地使用资源，实现其目标，并在必要时，调整中心的目标，作为研究 问题、挑战、机遇和支持需求不断变化。 目标3.促进核心中心机构和研究者之间的互动和沟通。 理由：使跨学科的互动，合作和有效的沟通促进 凝聚力、创造力和生产力。