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Core B Modeling Core

核心 B 建模核心

基本信息

批准号：
10569053
负责人：
RONA S SCOTT
金额：
$ 36.29万
依托单位：
LOUISIANA STATE UNIV HSC SHREVEPORT
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-03-01 至 2026-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10569053
关键词：
Area Behavior Big Data Bioinformatics Biological Centers of Research Excellence Clinical Informatics Complex Data Analyses Development Disease Education Ensure Experimental Designs Extramural Activities Faculty Fee-for-Service Plans Fostering Funding Future Gene Activation Gene Expression Gene Proteins Genes Genetic Genomics Goals Healthcare Hospitals Human Resources Immune response Immunological Models Immunologics Immunology Individual Inflammation Informatics Infrastructure Invaded Knowledge Mediator Methods Microarray Analysis Modeling Molecular Mutation Outcome Pathologic Pathologic Processes Pathway Analysis Pathway interactions Postdoctoral Fellow Productivity Proteins Proteome Publications Research Research Activity Research Personnel Resources Secure Services Software Tools Stimulus Students System Technical Expertise Technology Tissues Training Programs Training and Education Universities Work bioinformatics infrastructure complex data computer infrastructure computer science computerized tools experience faculty research genetic predictors genetic regulatory protein innovation mathematical model meetings network models next generation sequencing novel pathogen programs response skills student training success tumor undergraduate student virology whole genome

项目摘要

PROJECT ABSTRACT The goals of the COBRE Center for Applied Immunology and Pathological Processes (CAIPP) are to establish a nationally recognized advanced research and training program to understand immunological contributions in various disease states and facilitate the development of junior faculty research programs to achieve major independent research funding. Application of networking analysis and modeling approaches to immunological questions is capable of predicting genetic mediators and modeling immune outcomes in response to various pathogens and disease states. The Center for Applied Immunology and Pathological Processes proposes to develop a Modeling Core (Core B) to support the CAIPP research activities. The goals of the Modeling Core are to provide access to technical and scientific expertise that advances individual COBRE investigator projects. The Modeling Core will bring needed infrastructure to drive hypotheses, expedite publications, and enhance our competitiveness for extramural funding. Education and training initiatives will increase the systems-based bioinformatics knowledge at LSUHSC-S and inspire others to pursue bioinformatics in their research.

项目摘要科布雷应用免疫学和病理过程中心(CAIPP)的目标是建立国家认可的高级研究和培训计划，以了解免疫方面的贡献各种疾病状态，并促进初级教师研究计划的发展，以实现主要独立研究基金。网络分析和建模方法在免疫学中的应用问题能够预测遗传中介并模拟免疫结果，以响应不同的病原体和疾病状态。应用免疫学和病理过程中心建议开发一个建模核心(核心B)来支持CAIPP的研究活动。建模核心的目标是提供获得技术和科学专业知识的途径，以促进个别科布雷调查员项目的发展。这个建模核心将带来必要的基础设施来推动假设，加快发布速度，并增强我们的争取外部资金的竞争力。教育和培训举措将增加基于系统的 S大学的生物信息学知识，并激励其他人在他们的研究中追求生物信息学。