Biopsychosocial predictors of tumor-associated inflammation and progression

项目总结 庞塞健康科学大学RCMI项目的拟议管理结构 (PHSU)将使用多PL选项。何塞·A·托雷斯-鲁伊斯博士和理查德·诺埃尔博士将担任 时间和精力加起来只有50%。两位私人助理都是备受尊敬的学术领袖，并具有互补性 作为RCMI计划的复杂企业的有效日常管理所需的专业知识 在PHSU。拟议的绩效指标将直接向主管研究的副总裁办公室报告，后者反过来 向该机构的总裁汇报。两名私家侦缉人员将获授权及 机构支持，以有效和高效地领导拟议的RCMI计划。行政核心 将得到内部咨询委员会和外部咨询委员会的密切协助 (东区议会)。在下一个资助周期内，咨询委员会将积极努力建立和 培养富有成效的伙伴关系和合作，目的是：(1)建立和扩大 与RCMI以及全国各地的非RCMI机构的研究合作的数量和质量， 以及(2)提高PHSU RCMI项目的能力，以追求有竞争力的主流项目 基础、临床和转化性研究，重点放在健康差异方面。本节还考虑了一个 职业提升机会计划。在下一个五年筹资周期中，我们致力于促进 建立一支新的翻译科学家队伍，致力于解决少数群体的健康和 健康差距问题。这一构成部分下的拟议活动主要针对初级教员， 博士后研究员以及对从基础到 翻译研究。这些努力与我们下一步的机构研究战略计划是一致的 五年(旨在增加生物医学研究人员的招聘、留住和晋升)和 与NIMHD的总体愿景和使命一致)。提议的目标将由一系列专业人士 发展活动包括一系列研讨会、讲习班、短期课程以及其他倡议。这个 AC部分进一步提供了评估计划继续建设的有效性的评估计划 开发高质量的基础、行为、临床和转化性研究的研究基础设施 特别强调少数群体健康和健康差距的活动。一个外部团队将对 方案在履行总体方案任务及其核心目标方面的进展情况 衡量在实现短期、中期和长期目标方面取得的进展。

PROJECT SUMMARY The proposed Administrative Structure for the RCMI Program at the Ponce Health Sciences University (PHSU) will utilize the multi-Pl option. Drs. Jose A. Torres-Ruiz and Richard Noel will serve as PIs with a combined time and effort of 50%. Both PIs are well respected academic leaders and have complementary expertise needed for the effective day-to-day management of a complex enterprise as the RCMI Program at PHSU. The proposed PIs will report directly to the office of the Vice President for Research, who in turn reports to the institution's President. Both PIs will be empowered with the necessary authority and institutional support to effectively and efficiently lead the proposed RCMI Program. The Administrative Core will be closely assisted by the Internal Advisory Committee (IAC) and the External Advisory Committee (EAC). During the next funding cycle, the AC will intend to launch an aggressive effort in establishing and nurturing productive partnerships and collaborations with the purpose of; (1) establishing and expanding the number and quality of the research collaborations with RCMI as well as non-RCMI institutions around the nation, and (2) increasing the capacity of the RCMI Program at PHSU to pursue competitive, mainstream, programs in basic, clinical, and translational research with emphasis in health disparities. This section also contemplates a career enhancement opportunity program. During the next five-year funding cycle, we are committed to promote the establishment of a new cadre of translational scientists with an interest in addressing minority health and health disparities issues. The proposed activities, under this component, targets predominantly junior faculty, Post-Doctoral Fellows as well as middle career scientists with an interest in transitioning from basic to translational research. These efforts are consonant with our Institutional Strategic Plan for Research for the next five years (intended to augment the recruitment, retention, and advancement of biomedical researchers) and with the general vision and mission of NIMHD). The proposed goal will be approached by a series of professional development activities including; a seminar series, workshops, short courses, as well as other initiatives. The AC section further presents an Assessment Plan to evaluate the effectiveness of Program to continue building research infrastructure to development of high quality basic, behavioral, clinical, and translational research activities with strong emphasis on minority health and health disparities. An external team will evaluate the progress of the program in fulfilling the mission of the overall program and its core objectives based on the measure of progress toward achieving short-term, medium-term, and long-term goals.