Biomedical Statistics Core

生物医学统计核心 进食行为生物行为机制研究中心 摘要/摘要 我们建议在桑福德生物医学中心建立一个生物医学研究卓越中心(COBRE)。 行为研究(SCBR；新泽西州法戈)与北达科他州立大学(NDSU)合作 心理学和药学系和北达科他州大学医学院 医学(联合国开发计划署)。该中心将专注于开展前沿、创新性的研究 与进食障碍和进食行为的发生和维持有关的机制。目的 生物医学统计核心(BSC)是创建支持的方法和统计基础设施 临床和转化性研究和教育侧重于与发病和死亡相关的机制 维持进食障碍和进食行为。这个核心将允许有效地访问方法论 和生物统计支助，提供咨询、方法和统计支助服务， 教育活动，以及方法和统计指导和培训机会。 目标 1.在桑福德生物行为研究中心开发和实施平衡计分卡，将提供和 保持高质量的临床和统计咨询和支持服务 进食障碍发病和维持机制的翻译研究 进食行为。 2.为Cobre项目主任提供方法学和统计教育机会 教师以研讨会、座谈会和研讨会的形式。这些教育机会将集中在 识别和评价机械过程的方法。 3.为Cobre项目主管和教职员工提供指导和实践培训机会 有兴趣获得分析经验，并进一步发展其统计和方法技能。 方法 BSC将在拨款前、拨款和拨款后期间与Cobre项目主管合作， 协助研究设计、样本量计算、能量分析、数据收集方法、数据存储和 管理、正在进行的研究监测、统计分析、结果解释和协助 准备演示文稿和出版物。平衡计分卡将与行政核心和人力资源一起工作 学科核心是在研究的道德行为领域提供相关的培训机会， 研究设计(例如，样本量计算和功率分析)、机械性数据分析方法、 助学金写作和职业发展。除了这些培训机会，平衡计分卡还将 以持续指导或定期项目实践培训的形式提供更密集的培训 有兴趣扩展其分析能力的董事。

Biomedical Statistics Core Center for Bio-behavioral Mechanisms of Eating Behavior SUMMARY/ABSTRACT We propose to establish a Center of Biomedical Research Excellence (COBRE) at the Sanford Center for Bio- behavioral Research (SCBR; Fargo, ND) in collaboration with the North Dakota State University (NDSU) Departments of Psychology and Pharmaceutical Sciences and the University of North Dakota School of Medicine (UNDSOM). This center will focus on conducting cutting-edge, innovative research on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. The purpose of the Biomedical Statistics Core (BSC) is to create a methodological and statistical infrastructure supporting clinical and translational research and education focused on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. This core will allow efficient access to methodological and biostatistical support by providing consultation, methodological and statistical support services, educational activities, and methodological and statistical mentoring and training opportunities. Objectives 1. To develop and implement a BSC at Sanford Center for Bio-behavioral Research that will provide and maintain high quality methodological and statistical consultation and support services for clinical and translational research on the mechanisms related to the onset and maintenance of eating disorders and eating behaviors. 2. To provide methodological and statistical educational opportunities for COBRE Project Directors and faculty in the form of seminars, colloquia, and workshops. These educational opportunities will focus on methods for identifying and evaluating mechanistic processes. 3. To provide mentoring and hands-on training opportunities for COBRE Project Directors and faculty interested in gaining analytic experience and further developing their statistical and methodological skills. Methods The BSC will work with the COBRE Project Directors during the pre-grant, grant, and post-grant periods, assisting in study design, sample size calculation, power analysis, data collection methods, data storage and management, ongoing study monitoring, statistical analysis, interpretations of results, and assistance in preparation of presentations and publications. The BSC will work with the Administrative Core and Human Subjects Core to provide relevant training opportunities in the areas of the ethical conduct of research, research design (e.g., sample size calculation and power analysis), mechanistic data analytic approaches, grant writing, and professional development. In addition to these training opportunities, the BSC will also provide more intensive training in the form of ongoing mentoring or regular hands-on training for Project Directors who are interested in expanding their analytic capabilities.