How bacterial SMC complexes organize chromosomes (Equipment Supplement)

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Project Summary The primary goal of our funded research (1R01GM141242) is to understand how the chromosome is organized and segregated during the cell cycle. We focus on the molecular mechanisms of SMC condensin complex, which is a key player for chromosome dynamics from bacteria to humans. Our projects combine genetic, molecular, cytological, and biochemical approaches. All of these approaches require that we grow the bacterial cells to the desired experimental conditions. In this application for Administrative Supplements for Equipment, I am requesting the New Brunswick Innova 44R system, which will allow us to continue growing cells to perform the experiments proposed in the parent grant.