Human Physiology Core

人类生理学核心提供最先进的、经济高效的集中化服务，用于评估 生化分析、人体成分和能量代谢、胰岛素敏感性和β细胞功能 与糖尿病相关的研究。为此，核心维护仪器、收集和提供 质量控制数据，维护和提供基于网络的调度系统，并提供训练有素的人员配置 技术人员提供广泛的措施和服务，以满足小型飞行员的需求 最高可达R01级大型协议的学习和学生项目。此外，核心推动多学科 在UAB校园内进行糖尿病研究，并为学生、研究员和 教职员工。最后，核心有助于方法论在以下领域的发展、演变和扩展 通过实施和验证新的技术和方法，在UAB治疗糖尿病。这项服务提供的新技术 项目期间包括通过磁共振成像对肾窦脂肪进行分析。开发工作包括 使用干血斑点分析来自提供远程样本的研究参与者的激素。《人类》 生理学核心在将基础研究成果转化为理解的过程中发挥着核心作用 导致糖尿病和心脏代谢性疾病的人类生理学和病理生理学机制。

The Human Physiology Core provides state-of-the-art, cost-effective, centralized services for assessment of biochemical analytes, human body composition and energy metabolism, insulin sensitivity, and beta-cell function for diabetes-related research studies. Toward this end, the Core maintains instruments, collects and provides quality control data, maintains and offers a web-based scheduling system, and provides staffing by trained technical personnel for a broad suite of measures and services that can accommodate the needs of small pilot studies and student projects up to large R01-level protocols. In addition, the Core promotes multi-disciplinary research in diabetes across the UAB campus, and offers training, advice, and instruction to students, fellows, and faculty. Lastly, the Core contributes to the development, evolution, and expansion of methodology in field of diabetes at UAB by implementing and validating new technology and methodology. New technology offered in this project period includes analysis of renal sinus fat from magnetic resonance imaging. Developmental work includes use of dried blood spots for analysis of hormones from study participants providing remote samples. The Human Physiology Core plays a central role in the DRC in the translation of basic research findings into an understanding of human physiology and pathophysiological mechanisms causing diabetes and cardiometabolic disease.