Research Infrastructure Core

项目总结： 研究基础设施核心(RIC)的长期目标是支持、加强和扩大 佛罗里达农工大学(FAMU)的生物医学和行为研究项目。在过去三年中 几十年来，通过积极的研究支持，FAMU PIS取得了巨大的成功 RCMI计划的基础设施组成部分。FAMU的研究人员依靠提供的服务 因为使用关键的仪器分析和研究人员来收集数据，这些数据被用来编写NIH 建议，制定和维持资助项目，在被引用和编入索引的科学期刊上发表，如 以及成功地培养研究生。现在迫切需要振兴这些支持。 继续加强校园生物医学和行为研究活动的战略。焦点 FAMU RCMI U54研究基础设施的核心将是促进创新技术， 支持建议的RCMI研究项目、试点项目和其他FAMU生物医学和行为学 解决少数族裔、农村和农村地区的健康差距问题的研究计划 以及城市贫困人口和其他医疗服务不足的人群。RIC将提供最先进的 分析设施包括蛋白质组学、流式细胞术和成像、高通量筛选 (HTS)，核磁共振，分子建模技术，细胞因子，微阵列和表观遗传学分析和数据 管理；2)加强和发展药物发现和开发方面的研究技能和能力 通过提供新技术、培训教师和其他研究人员使用 核心设施；以及3)通过提供讲习班、研讨会和 药物发现和生物技术研究应用方面的短期课程，以加强研究 熟练程度。支持基础设施核心意义重大，因为它促进了有意义的 协作，允许共享资源并为以下方面提供发展和培训机会 少数族裔科学家。此外，拟议的研究基础设施核心与NIH/NIMHD相关 与发展研究基础设施和培训调查人员有关的任务 在生物医学和行为学领域获得有竞争力的外部支持方面变得更加成功 研究。

Project Summary: The long-term goal of the Research Infrastructure Core (RIC) is to support, strengthen and expand biomedical and behavioral research projects at Florida A&M University (FAMU). Over the past three decades, tremendous success was achieved by FAMU PIs through the active support of the research infrastructure component of the RCMI Program. FAMU researchers relied on the services provided such as using key instrumental analysis and research personnel to gather data that were used to write NIH proposals, develop and sustain funded projects, publish in refereed and indexed scientific journals, as well as train graduate students successfully. There is a critical need now to invigorate these support strategies to continue strengthening biomedical and behavioral research activities on campus. The focus of the FAMU RCMI U54 Research Infrastructure Core will be on promoting innovative technologies that support the proposed RCMI research projects, pilot projects, and other FAMU biomedical and behavioral research initiatives that address health disparities experienced by racial and ethnic minorities, the rural and urban poor and other medically underserved populations. The RIC will 1) provide state-of-the-art analytical facilities including Proteomics, Flow Cytometry and Imaging, High Throughput Screening (HTS), NMR, Molecular Modeling Techniques, Cytokine, Microarray and Epigenetics Analysis and Data Management; 2) enhance and develop research skills and capabilities in drug discovery and biotechnology by providing new technologies, training of faculty and other researchers in the use of the facilities of the core; and 3) promote and develop knowledge by providing workshops, seminars and short courses in drug discovery and biotechnology research applications to enhance research proficiency. Supporting the infrastructure core is significant because it promotes meaningful collaborations, allows sharing of resources and provides developmental and training opportunities for minority scientists. In addition, the proposed Research Infrastructure Core is relevant to the NIH/NIMHD mission pertaining to the development of the research infrastructure and training of investigators to become more successful in obtaining competitive extramural support in biomedical and behavioral research.