Leveraging an academic-industry partnership to develop a cancer-specific mobile meditation app

利用学术与行业合作伙伴关系开发针对癌症的移动冥想应用程序

基本信息

批准号：
10253517
负责人：
Jennifer Lynne Huberty
金额：
$ 39.77万
依托单位：
CALM.COM, INC.
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-03-01 至 2022-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10253517
关键词：
Address Advisory Committees Affect Android Anxiety Behavioral Benchmarking Cancer Center Cancer Patient Cancer Survivor Cellular Phone Clinic Clinical Cognitive Data Development Disease Management Emotions Evaluation Facebook Fatigue Feasibility Studies Feedback Focus Groups General Population Grief reaction Health Health Care Costs Health Personnel Healthcare Systems Impairment Infrastructure Insurance Intention Intervention Interview Letters Malignant Neoplasms Meditation Mental Depression Methods Mindfulness Training Modeling Modification Monitor Pain Patients Performance Persons Phase Population Positioning Attribute Provider Quality of life Randomized Randomized Controlled Trials Reporting Research Research Personnel Residual state Sampling Schedule Scientist Sleep disturbances Social support Suggestion Surveys Survivors Symptoms System Techniques Testing Trauma Travel Work base commercialization cost design disability eHealth efficacy testing evidence base experience fitness flexibility health care service utilization improved industry partner innovation interest mHealth mobile application novel patient population persistent symptom programs prototype psychologic reduce symptoms satisfaction social social cognitive theory standard of care survivorship symptom management symptomatic improvement tool uptake

项目摘要

1 Project Summary/Abstract 2 Approximately 15.5 million US cancer patients/survivors experience a host of residual symptoms (e.g., 3 fatigue, anxiety, depression, pain, sleep disturbance) and reduced quality of life that are often not resolved with 4 even the best-available current standard of care therapies. Residual symptom burden impairs cancer survivor 5 functioning and leads to increased rates of disability and healthcare utilization, costing $125 billion every year. 6 Cancer patients/survivors want and need complementary strategies to accompany standard therapies. 7 Research has demonstrated the benefits of mindfulness-based therapies, such as meditation, for 8 alleviating cancer-related symptoms (e.g., fatigue, anxiety, depression, and sleep disturbance).Meditation-based 9 programs are typically conducted in-person, in clinic settings; however, these programs are expensive and 10 difficult to sustain, and cancer patients report barriers to participating (e.g., travel demands, fatigue, pain, and 11 scheduling difficulties). Smartphone-based meditation is a feasible and novel method for delivering meditation 12 to cancer patients/survivors. Mobile apps and online meditation programs have demonstrated short-term benefits 13 for cancer patients/survivors; however, the currently available commercial meditation apps are limited in their 14 engagement, acceptability, and applicability to cancer patients/survivors’ unique experiences and have not been 15 evaluated for feasibility or efficacy. There is an unmet need for a commercially-available, evidence-based 16 meditation app specifically designed for cancer patients/survivors. Incorporating stakeholder feedback (i.e., 17 patients and healthcare providers) in the early design phase will facilitate the development of a meditation app 18 truly targeted for the end users that can be made commercially available, thereby improving uptake and impact 19 in patient populations. Calm, a popular consumer-based meditation app with 70 million downloads and 2 million 20 subscribers, provides a platform from which to develop an accessible standalone cancer-specific meditation app. 21 This project will: 1) gather feedback about the current Calm app from an advisory committee (N=20) consisting 22 of cancer patients/survivors (n=10, 5 of each) and healthcare providers (n=10), 2) design a cancer-specific 23 meditation app prototype, and 3) beta-test the prototype in cancer patients/survivors (N=30). 24 A standalone meditation app designed for and tested by cancer patients/survivors, leveraging a popular 25 and validated meditation app platform, to be made commercially available, is innovative and could provide a 26 scalable, highly engaging symptom-management tool that addresses cancer patients/survivors’ unique needs. 27 If our key feasibility milestones are met, we will further refine the cancer-specific app and conduct a randomized 28 controlled trial to determine the app’s long-term efficacy in reducing symptom burden in cancer patients/survivors 29 (Phase 2) that can later be commercialized and marketed to cancer patients/survivors, healthcare providers, and 30 clinics. (Phase 3).

1个项目摘要/摘要 2大约1550万美国癌症患者/幸存者经历了许多残留症状（例如， 3疲劳，焦虑，抑郁，疼痛，睡眠障碍）和生活质量降低，而生活质量通常无法解决 4即使是目前最好的护理疗法标准。残留症状伯宁损害癌症幸存者 5功能并导致残疾和医疗保健利用率增加，每年耗资1250亿美元。 6个癌症患者/幸存者需要并需要完整的策略来适应标准疗法。 7研究表明，基于正念的疗法（例如冥想）的好处 8缓解与癌症相关的症状（例如疲劳，动画，抑郁和睡眠障碍）。通常在诊所环境中进行9个计划；但是，这些程序很昂贵， 10难以维持，癌症患者报告了参与的障碍（例如，旅行需求，疲劳，疼痛和 11安排难度）。基于智能手机的冥想是一种可行且新颖的方法来提供冥想癌症患者/幸存者12。移动应用程序和在线冥想计划已经证明了短期福利癌症患者/幸存者13；但是，当前可用的商业冥想应用程序受到限制 14对癌症患者/幸存者独特经历的参与，可接受性和适用性 15评估可行性或效率。不满足商业上可用的，基于证据的需求 16专为癌症患者/幸存者设计的冥想应用程序。合并利益相关者的反馈（即 17例患者和医疗保健提供者）在早期设计阶段将有助于开发冥想应用程序 18真正针对可以在市售的最终用户的目标，从而改善了吸收和影响 19位患者人群。镇静，一个受欢迎的基于消费者的冥想应用程序，下载7000万个和200万 20个订户提供了一个平台，可以从该平台开发一个可访问的独立癌症特异性药物应用程序。 21该项目将：1）收集有关咨询委员会（n = 20）的当前平静应用的反馈，该应用程序包括 22例癌症患者/幸存者（n = 10，5）和医疗保健提供者（n = 10），2）设计一种癌症特异性的 23冥想应用程序原型和3）β-检验癌症患者/幸存者的原型（n = 30）。 24一个独立的冥想应用程序，由癌症患者/幸存者设计和测试，利用流行 25和经过验证的冥想应用程序平台，可在市售上可用，具有创新性，可以提供 26可扩展，高度引人入胜的症状管理工具，可满足癌症患者/幸存者的独特需求。 27如果达到了我们的关键可行性里程碑，我们将进一步完善特定于癌症的应用程序并进行随机进行 28对照试验，以确定该应用程序在降低癌症患者/幸存者症状的长期效率方面的长期效率 29（第2阶段），后来可以商业化并向癌症患者/幸存者，医疗保健提供者和 30个诊所。（第3阶段）。