Consumer-based meditation app, Calm, for treatment of sleep disturbance in hematological cancer patients

基于消费者的冥想应用程序 Calm,用于治疗血液癌症患者的睡眠障碍

基本信息

  • 批准号:
    10444598
  • 负责人:
  • 金额:
    $ 9.58万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-04-01 至 2022-07-31
  • 项目状态:
    已结题

项目摘要

Hematological cancers, a group of cancer sub-types that include blood- and lymph-related disorders (i.e., leukemia, lymphoma, myeloma, myeloproliferative neoplasms (MPNs) and myelodysplastic syndromes (MDS), account for 11% of all cancer diagnoses in the US. Chronic hematological cancer (CHC) patients (i.e., chronic leukemias, low grade lymphomas, myeloma, myelodysplastic syndrome, and myeloproliferative neoplasms [MPNs]) have extended disease courses that are often different from solid tumor cancers, facing chronic sleep disturbances often associated with inflammation, fatigue, and emotional distress (anxiety and depression), which often persist into survivorship. Medications are most commonly prescribed for cancer patients with sleep disturbance; however, they often come with side effects and risk for long-term dependence. Cognitive behavioral therapy for insomnia (CBT-I) is the most studied and first line of therapy for treating sleep disturbances in cancer patients, but CBT-I is time-consuming, resource-intensive, and not easily accessible for all cancer patients. There is a need for long-term, accessible, non-pharmacologic interventions targeting sleep in CHC patients. Meditation is a safe and effective non-pharmacologic approach for improving a range of cancer-related symptoms. However, meditation interventions have typically been delivered in-person, limiting uptake and widespread dissemination due to patient-reported barriers. Smartphone applications (apps) are a novel intervention approach for delivering meditation and address cancer patients’ barriers to participating in in-person interventions (i.e., fatigue, pain, transportation, and scheduling difficulties) without the time and expertise limitations of CBT-I and side effect risks from medication. Calm is a popular and highly reviewed consumer- based smartphone app that provides an innovative, accessible and scalable platform through which to deliver meditation to CHC patients. We propose a double-blind RCT to determine the effectiveness of an eight-week “app-based wellness” intervention (i.e., active daily meditation intervention [Calm] or the placebo health education podcast control group [POD]) to reduce sleep disturbance (primary outcome), markers of inflammation (TNF-a, IL-6, IL-8, and CRP) fatigue, and emotional distress (anxiety, depression) (secondary outcomes) in CHC patients. Assessments will occur at baseline, post-intervention (eight weeks from baseline), and follow-up (20 weeks from baseline). Participants (N=276) will be randomized to an intervention (10 min/day Calm meditation) (n=138) or control (10 min/day health education podcast) group (n=138). We will remotely collect blood samples for biomarker measurement. This study will fill a knowledge and rigor gap regarding the delivery of smartphone- based meditation as an intervention for sleep and provide new data on sustained effects in CHC patients to reduce sleep disturbance.
血液学癌症是一组癌症亚型,包括血液和淋巴相关疾病(即白血病、淋巴瘤、骨髓瘤、骨髓增生性肿瘤(mpn)和骨髓增生异常综合征(MDS)),占美国所有癌症诊断的11%。慢性血液癌(CHC)患者(即慢性白血病、低级别淋巴瘤、骨髓瘤、骨髓增生异常综合征和骨髓增生性肿瘤)

项目成果

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Jennifer Lynne Huberty其他文献

Jennifer Lynne Huberty的其他文献

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{{ truncateString('Jennifer Lynne Huberty', 18)}}的其他基金

Consumer-based meditation app, Calm, for treatment of sleep disturbance in hematological cancer patients
基于消费者的冥想应用程序 Calm,用于治疗血液癌症患者的睡眠障碍
  • 批准号:
    10570259
  • 财政年份:
    2022
  • 资助金额:
    $ 9.58万
  • 项目类别:
Using Mobile Technology to Reduce Stress in Caregivers of Persons with Dementia. A Scalable Solution to A Growing Problem
使用移动技术减轻痴呆症患者护理人员的压力。
  • 批准号:
    10677680
  • 财政年份:
    2022
  • 资助金额:
    $ 9.58万
  • 项目类别:
Consumer-based meditation app, Calm, for treatment of sleep disturbance in hematological cancer patients
基于消费者的冥想应用程序 Calm,用于治疗血液癌症患者的睡眠障碍
  • 批准号:
    10684545
  • 财政年份:
    2022
  • 资助金额:
    $ 9.58万
  • 项目类别:
Using Mobile Technology to Reduce Stress in Caregivers of Persons with Dementia. A Scalable Solution to A Growing Problem
使用移动技术减轻痴呆症患者护理人员的压力。
  • 批准号:
    10523227
  • 财政年份:
    2022
  • 资助金额:
    $ 9.58万
  • 项目类别:
Leveraging an academic-industry partnership to develop a cancer-specific mobile meditation app
利用学术与行业合作伙伴关系开发针对癌症的移动冥想应用程序
  • 批准号:
    10253517
  • 财政年份:
    2021
  • 资助金额:
    $ 9.58万
  • 项目类别:
Yoga online: Inter-conception care to prevent PTSD symptoms after stillbirth
在线瑜伽:孕间护理可预防死产后的创伤后应激障碍症状
  • 批准号:
    9319625
  • 财政年份:
    2016
  • 资助金额:
    $ 9.58万
  • 项目类别:
Yoga online: Inter-conception care to prevent PTSD symptoms after stillbirth
在线瑜伽:孕间护理可预防死产后的创伤后应激障碍症状
  • 批准号:
    9143370
  • 财政年份:
    2016
  • 资助金额:
    $ 9.58万
  • 项目类别:

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