ADMIN CORE

项目概要（BBDC管理核心） BBDC行政核心将在总体PI的指导下协调和实施BBDC 博士布伦丹李，共同PI特雷西哈特，和临床团队联络博士V里德萨顿。它还将协调 临床站点、核心站点和患者倡导站点之间的相互作用。为了实现这一目标，核心将跟踪 并促进资金转移和参与网站之间的分包合同，安排和准备议程， 执行委员会、PI指导委员会和研究中心每月分别召开电话会议 协调员。核心将协调年度BBDC亲自会议与年度 成骨不完美基金会科学会议，并促进年度Geisman培训奖学金 竞争最后，该核心将管理和审查a）法语国家组织提供的临床培训研究金，B）试点 项目申请，c）请求获取在纵向研究中收集的生物标本，d） 影像学中心的集中放射学阅读和质量/评估，并协调e）年度 外部咨询委员会审查和f）为单一机构编制行政文件 审查委员会（sIRB）和数据和安全性监查委员会（DSMB）审查。核心将负责 BBDC与更广泛的RDCRN和参与者社区之间的所有通信。

PROJECT SUMMARY (BBDC Administrative Core) The BBDC administrative core will coordinate and implement the BBDC under the direction of the overall PI Dr. Brendan Lee, co-PI Tracy Hart, and Clinical Team Liaison Dr. V. Reid Sutton. It will also coordinate the interactions among the clinical sites, cores, and the patient advocacy site. To achieve this, the Core will track and facilitate funds transfer and subcontracts between participating sites, schedule and prepare agendas for monthly teleconferences separately for the executive committee, the PI-steering committee, and site coordinators. The Core will coordinate the annual BBDC in person meeting in conjunction with the annual Osteogenesis Imperfecta Foundation Scientific Meeting, and facilitate the annual Geisman training fellowship competition. Finally, the core will administer and review a) clinical training fellowships by the OIF, b) pilot project applications, c) requests for access to bio-specimens collected within the longitudinal study, d) centralized radiographic reading and quality/assessment of imaging sites, and coordinate e) the annual external advisory committee review and f) administrative preparation of documents for single Institutional Review Board (sIRB) and Data and Safety Monitoring Board (DSMB) review. The Core will be responsible for all communications between the BBDC and the broader RDCRN and Participant communities.