Core G: Research Education Component (RL5)

抽象研究教育组成部分 研究教育部分(REC)的总体目标是培养高素质的研究人员 在病因、发病机制、诊断、治疗和预防的变革性跨学科研究中 阿尔茨海默氏症及相关痴呆症(AD/ADRD)。最近的进展，特别是在应用 高通量生化和分子技术以及整合多水平和 多民族数据为科学进步提供了前所未有的机遇，但也为 从事老龄化研究的调查人员。优化高影响力研究中的新兴方法 需要有才华的科学家能够跨学科分享知识和方法。真的 然而，跨学科研究可能很难完成。障碍包括有限的共享知识 在来自不同学科和该领域不断变化的动态的调查人员中；初级调查人员 越来越多的人拥有新兴方法方面的专业知识，但可能缺乏对其潜力的充分认识 解决知识中的关键差距，对这些差距有深入了解的高级调查人员可能会 不熟悉新兴的方法论。新的综合和多方向的学习机会(即， 需要来自不同学科和机构的各级调查人员的学习流)，以促进高效 不同调查人员之间的知识转让和富有成效的伙伴关系。REC将利用一项 高度多学科的教师，并实施综合和多方向的方法，以促进真正 跨学科的老龄化研究，重点关注新兴方法和高度优先的领域，如健康 差距。为此，REC将在与老龄化相关的关键学科中提供跨学科培训 并将其与新兴方法和健康差异研究的新培训联系起来，使用高度独特的 在Rush生成的临床、生物和生物质谱学数据。REC将与所有其他Rush ADRC核心一起工作 执行和监督各种教育活动，包括1)每月一次的神经流行病学 老龄化研讨会；2)关于新方法和健康差距的强化小型实习培训，3) 个性化指导，以及4)参加老龄化研究中心的年度论坛。通过细心 与Rush ADRC的其他核心相结合，REC将培养高技能的跨学科调查人员 能够在高影响力和创新性的AD/ADRD研究中利用当代方法。

ABSTRACT – RESEARCH EDUCATION COMPONENT The overall goal of the Research Education Component (REC) is to develop high quality investigators engaged in transformative interdisciplinary research on the etiology, pathogenesis, diagnosis, treatment, and prevention of Alzheimer’s dementia and related dementias (AD/ADRD). Recent advances, particularly the application of high throughput biochemical and molecular techniques and novel approaches to integrate multilevel and multiethnic data, offer an unprecedented opportunity for scientific progress but also pose unique challenges for investigators engaged in aging research. Optimization of emerging methodologies in high impact research requires talented scientists capable of sharing knowledge and methodologies across disciplines. Truly interdisciplinary research can be difficult to accomplish, however. Barriers include limited shared knowledge among investigators from diverse disciplines and changing dynamics in the field; junior investigators increasingly hold expertise in emerging methodologies but may lack a full appreciation of their potential to address critical gaps in knowledge, and senior investigators with a deep understanding of these gaps may be unfamiliar with emerging methodologies. New integrative and multidirectional learning opportunities (i.e., learning flows from investigators of all levels across disciplines and institutions) are needed to facilitate efficient knowledge transfer and productive partnership among diverse investigators. The REC will capitalize on a highly multidisciplinary faculty and implement an integrative and multidirectional approach to facilitate truly interdisciplinary aging research with a focus on emerging methodologies and high priority areas such as health disparities. Toward this end, the REC will provide cross-disciplinary training in key disciplines relevant to aging and link this to new training in emerging methodologies and health disparities research using the highly unique clinical, biologic and biospecimen data generated at Rush. The REC will work with all other Rush ADRC Cores to implement and oversee a variety of educational activities, including 1) a monthly Neuroepidemiology of Aging Seminar; 2) intensive mini-internship training in emerging methodologies and health disparities, 3) individualized mentoring, and 4) participation in the RADC annual Aging Research Forum. Via careful integration with the other Rush ADRC Cores, the REC will develop highly skilled interdisciplinary investigators capable of leveraging contemporary approaches in high impact and innovative AD/ADRD research.