HD2A RASC - Pain Implementation Support Core
HD2A RASC - 疼痛实施支持核心
基本信息
- 批准号:10596438
- 负责人:
- 金额:$ 61.88万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-09-30 至 2027-08-31
- 项目状态:未结题
- 来源:
- 关键词:AcademyAcuteAddressAdoptionAdverse effectsAdvocacyAmericanAmericasAttentionBehavior TherapyBehavioralCaringCatalogsCenters for Disease Control and Prevention (U.S.)Cessation of lifeChargeCommon Data ElementComplexData AnalyticsDevelopmentDiagnosisDimensionsDissemination and ImplementationEpidemicFundingGoalsGuidelinesHarm ReductionHealth StatusHealthcare SystemsImpairmentInstitute of Medicine (U.S.)InterventionLeadLearningLinkLong-Term EffectsLongevityMeasuresMediationMedicineMethodologyMethodsModelingMorbidity - disease rateMotivationOpioidOverdosePainPain ClinicsPain managementPain qualityPatientsPharmaceutical PreparationsPharmacological TreatmentPhasePlant RootsPoliciesPrevalencePreventionPublic HealthPublicationsQuality of CareQuality of lifeRecovery SupportReportingResearchResearch PersonnelRisk FactorsScienceScientistSignal TransductionTimeTranslatingUnited States National Institutes of Healthbasecare providerscareerchronic painchronic pain managementchronic pain patientdisabilitydissemination scienceeducation researchevidence baseevidence based guidelineshigh riskimplementation facilitationimplementation interventionimplementation measuresimplementation outcomesimplementation scienceimplementation strategyimplementation trialimprovedinnovationmemberopioid epidemicopioid overdoseopioid therapyopioid use disorderoverdose deathpain reliefpatient orientedpopulation healthpragmatic implementationprescription opioidprescription opioid misuseprogram disseminationresource guidesshared decision makingskillssocial stigmastemsymposiumtreatment guidelinesuptake
项目摘要
PAIN IMPLEMENTATION SUPPORT CORE: PROJECT SUMMARY/ABSTRACT
The ongoing opioid overdose crisis – the leading cause of accidental deaths among Americans – has at its
roots inadequately treated opioid use disorder (OUD) and pain. This reality has been recognized by the
National Academy of Medicine and the Centers for Disease Control and Prevention, among other major
organizations charged with protecting the public health, sparking an unprecedented influx of funding and policy
changes to stem the tide of overdose deaths. The nationwide attention and funding increase have driven a
marked rise in the development of evidence-based, high-quality pain treatments and treatment guidelines
addressing the full spectrum of public health need: from prevention to harm reduction to treatment to recovery
support. However, there has been woefully inadequate uptake of these treatments in real-world practice. For
example, primary care providers--the most frequent prescribers of long-term opioid therapy for pain--often lack
skills and/or time to fully implement evidence-based guidelines, putting already vulnerable patients at even
higher risk for opioid-related harms, including overdose, and poorly-controlled chronic pain. Effectively
translating research findings into practice and ameliorating these real-world quality of care deficits are the
domains of dissemination and implementation (D&I) science. As a key RASC core, the overarching goal of the
Pain Implementation Support (Pain-IS) Core is to support HD2A Innovation Projects in successful
implementation of effective pain interventions through the coordinated efforts of a highly expert collaborative
team, deploying and advancing cutting edge D&I methods. We will bring the best of D&I science to the pain
treatment quality gap, unifying implementation scientists and pain researchers—with the proximal goal of
enhancing research in the Innovation Projects and the ultimate goal of impacting the public health. Specifically,
in alignment with the other Cores, we will ASSESS the current status of key components of the Innovation
Projects on D&I capability in 5 key dimensions: a) evidentiary basis for the intervention; b) stakeholder
engagement c) contextual determinants; d) selection of implementation strategies; and, e) implementation
outcomes including the critically important but often overlooked domain of equity. We will ASSIST the
Innovation Projects using the information gathered in the ASSESS phase in order to: a) enhance motivation to
enhance their studies with tailored D&I approaches that draw upon the Core’s expertise; b) provide a D&I
Implementation Support Plan on the components above and using a shared decision-making approach to
determine how best to offer technical assistance (implementation support); and, c) to co-lead the RASC
Learning Collaborative. In concert with the RASC and other cores, we will ADVANCE the innovation projects
activities with respect to sustainment and equity: linking projects with the field at large, promoting projects’
impacts on policy/financing, and facilitating ongoing stakeholder engagement towards advocacy.
Pain实施支持核心:项目总结/摘要
正在进行的阿片类药物过量危机-美国人意外死亡的主要原因-已经在其
阿片类药物使用障碍(OUD)治疗不当和疼痛。这一现实得到了
国家医学科学院和疾病控制和预防中心,以及其他主要的
负责保护公众健康的组织,引发了前所未有的资金和政策涌入
改变以阻止过量死亡的浪潮。全国范围内的关注和资金增加推动了
基于证据的高质量疼痛治疗和治疗指南的发展显着增加
满足全方位的公共卫生需求:从预防到减少伤害,从治疗到康复
支持.然而,在现实世界的实践中,这些治疗方法的使用量远远不够。为
例如,初级保健提供者-长期阿片类药物治疗疼痛的最常见处方者-通常缺乏
充分实施循证指南的技能和/或时间,使已经脆弱的患者处于平衡状态
阿片类药物相关危害的风险更高,包括过量和控制不良的慢性疼痛。有效
将研究成果转化为实践并改善这些现实世界的护理质量缺陷是
传播和实施(D&I)科学。作为一个关键的RASC核心,
Pain实施支持(Pain-IS)核心是支持HD 2A创新项目的成功实施,
通过高度专家协作的协调努力,实施有效的疼痛干预措施
团队,部署和推进尖端的D&I方法。我们将把最好的D&I科学带到痛苦中,
治疗质量差距,统一实施科学家和疼痛研究人员-近端目标是
加强创新项目的研究,最终目标是影响公众健康。具体地说,
与其他核心项目保持一致,我们将评估创新项目关键组成部分的现状
关于D&I能力的5个关键方面的项目:a)干预的证据基础; B)利益攸关方
参与c)背景决定因素; d)实施策略的选择;以及,e)实施
这些成果包括至关重要但往往被忽视的公平领域。我们将协助
创新项目利用在评估阶段收集的信息,以便:a)提高动力,
利用核心小组的专门知识,采用量身定制的D&I方法,加强他们的研究; B)提供D&I
执行支助计划,并采用共同决策办法,
确定如何最好地提供技术援助(实施支持);以及,c)共同领导RASC
学习协作。与RASC和其他核心合作,我们将推进创新项目
在可持续性和公平方面的活动:将项目与整个实地联系起来,促进项目
对政策/筹资的影响,并促进利益攸关方持续参与宣传工作。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
WILLIAM C BECKER其他文献
WILLIAM C BECKER的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('WILLIAM C BECKER', 18)}}的其他基金
Multilevel Interventions to Reduce Harm and Improve Quality of Life for Patients on Long Term Opioid Therapy - Yale Resource Center (MIRHIQL-YRC)
多层次干预措施可减少长期阿片类药物治疗患者的伤害并提高其生活质量 - 耶鲁大学资源中心 (MIRHIQL-YRC)
- 批准号:
10722768 - 财政年份:2023
- 资助金额:
$ 61.88万 - 项目类别:
HD2A Research Adoption Support Center (RASC)
HD2A 研究采用支持中心 (RASC)
- 批准号:
10708980 - 财政年份:2022
- 资助金额:
$ 61.88万 - 项目类别:
Role of Non-pharmacological Pain Treatments in Safe and Effective Opioid Tapering in Chronic Pain
非药物疼痛治疗在安全有效地逐渐减少慢性疼痛中阿片类药物的作用
- 批准号:
10620195 - 财政年份:2022
- 资助金额:
$ 61.88万 - 项目类别:
HD2A Research Adoption Support Center (RASC)
HD2A 研究采用支持中心 (RASC)
- 批准号:
10596435 - 财政年份:2022
- 资助金额:
$ 61.88万 - 项目类别:
HD2A RASC - Pain Implementation Support Core
HD2A RASC - 疼痛实施支持核心
- 批准号:
10708984 - 财政年份:2022
- 资助金额:
$ 61.88万 - 项目类别:
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers
HEAL 计划:慢性疼痛和 OUD 整体康复综合管理 (IMPOWR):研究中心
- 批准号:
10876682 - 财政年份:2021
- 资助金额:
$ 61.88万 - 项目类别:
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers
HEAL 计划:慢性疼痛和 OUD 整体康复综合管理 (IMPOWR):研究中心
- 批准号:
10652027 - 财政年份:2021
- 资助金额:
$ 61.88万 - 项目类别:
HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers
HEAL 计划:慢性疼痛和 OUD 整体康复综合管理 (IMPOWR):研究中心
- 批准号:
10378910 - 财政年份:2021
- 资助金额:
$ 61.88万 - 项目类别:
Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in Veterans
实施整体健康团队与初级保健团体教育的务实试验,以促进非药物策略,改善退伍军人的疼痛、功能和生活质量
- 批准号:
10090568 - 财政年份:2020
- 资助金额:
$ 61.88万 - 项目类别:
Implementation of a Pragmatic Trial of Whole Health Team vs. Primary Care Group Education to Promote Non-Pharmacological Strategies to Improve Pain, Function and Quality of Life in Veterans
实施整体健康团队与初级保健团体教育的务实试验,以促进非药物策略,改善退伍军人的疼痛、功能和生活质量
- 批准号:
10533361 - 财政年份:2020
- 资助金额:
$ 61.88万 - 项目类别:
相似海外基金
Transcriptional assessment of haematopoietic differentiation to risk-stratify acute lymphoblastic leukaemia
造血分化的转录评估对急性淋巴细胞白血病的风险分层
- 批准号:
MR/Y009568/1 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Fellowship
Combining two unique AI platforms for the discovery of novel genetic therapeutic targets & preclinical validation of synthetic biomolecules to treat Acute myeloid leukaemia (AML).
结合两个独特的人工智能平台来发现新的基因治疗靶点
- 批准号:
10090332 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Collaborative R&D
Acute senescence: a novel host defence counteracting typhoidal Salmonella
急性衰老:对抗伤寒沙门氏菌的新型宿主防御
- 批准号:
MR/X02329X/1 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Fellowship
Cellular Neuroinflammation in Acute Brain Injury
急性脑损伤中的细胞神经炎症
- 批准号:
MR/X021882/1 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Research Grant
KAT2A PROTACs targetting the differentiation of blasts and leukemic stem cells for the treatment of Acute Myeloid Leukaemia
KAT2A PROTAC 靶向原始细胞和白血病干细胞的分化,用于治疗急性髓系白血病
- 批准号:
MR/X029557/1 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Research Grant
Combining Mechanistic Modelling with Machine Learning for Diagnosis of Acute Respiratory Distress Syndrome
机械建模与机器学习相结合诊断急性呼吸窘迫综合征
- 批准号:
EP/Y003527/1 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Research Grant
FITEAML: Functional Interrogation of Transposable Elements in Acute Myeloid Leukaemia
FITEAML:急性髓系白血病转座元件的功能研究
- 批准号:
EP/Y030338/1 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Research Grant
STTR Phase I: Non-invasive focused ultrasound treatment to modulate the immune system for acute and chronic kidney rejection
STTR 第一期:非侵入性聚焦超声治疗调节免疫系统以治疗急性和慢性肾排斥
- 批准号:
2312694 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Standard Grant
ロボット支援肝切除術は真に低侵襲なのか?acute phaseに着目して
机器人辅助肝切除术真的是微创吗?
- 批准号:
24K19395 - 财政年份:2024
- 资助金额:
$ 61.88万 - 项目类别:
Grant-in-Aid for Early-Career Scientists
Acute human gingivitis systems biology
人类急性牙龈炎系统生物学
- 批准号:
484000 - 财政年份:2023
- 资助金额:
$ 61.88万 - 项目类别:
Operating Grants