Novel Fluorogenic Probes for the Selective Detection of Pathogenic Bacteria

用于选择性检测病原菌的新型荧光探针

• 批准号: nhmrc : 1043746
• 负责人: Prof David Hibbs
• 金额: $ 36.17万
• 依托单位: Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-fluorogenic-probes-pathogenic-bacteria/111596
• 关键词: Novel; Fluorogenic; Probes; Selective; Detection

Current methods for the detection of multi-resistant organisms either require expensive instrumentation and expert analysts or are simple, but require 24-48 hours for bacterial identification. The ideal surveillance method would be cost effective, rapid, reliable, and simple to perform. This project aims to prepare a range of fluorescent substrates for incorporation into growth media which will then be evaluated for the specific identification of individual multi-resistant organisms, e.g. MRSA.

目前检测多重耐药微生物的方法要么需要昂贵的仪器和专业分析人员，要么很简单，但需要 24-48 小时进行细菌鉴定。理想的监测方法应具有成本效益、快速、可靠且易于执行。该项目旨在制备一系列荧光底物，用于掺入生长培养基中，然后对其进行评估，以具体鉴定单个多重耐药生物体，例如细菌。耐甲氧西林金黄色葡萄球菌。