Stimulating Access to Research in Residency (StARR) - NHLBI
Stimulating Access to Research in Residency (StARR) - NHLBI
批准号:
10597856
负责人:
Mai ElMallah
金额:
$31.48万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2018
资助国家:
美国
项目状态:
未结题
起止时间:
2018-07-01 至 2028-06-30
关键词:
AchievementAddressAffectApplications GrantsAreaAwardBasic ScienceBiomedical ResearchBloodBlood VesselsBoard CertificationCardiopulmonaryCardiovascular systemCaringClinicClinicalClinical ResearchClinical TrialsCommunicationCommunitiesCountryCritiquesData ScienceDedicationsDevelopmentDevelopment PlansDiagnosisDiseaseDisparityDrug KineticsEducationEducational workshopEligibility DeterminationEnsureEvaluationExtramural ActivitiesFacultyFellowshipFosteringFoundationsFundingGoalsGrantHealthHealthcareHeartHeart DiseasesHematological DiseaseHumanIndividualInfrastructureInstitutionJournalsLaboratory ResearchLife Cycle StagesLungLung diseasesManuscriptsMedicalMedicineMentorsMentorshipMethodsMissionModalityModernizationNational Heart, Lung, and Blood InstituteNational Institute of Allergy and Infectious DiseaseOperative Surgical ProceduresOutcomePathway interactionsPediatricsPeer ReviewPhasePhysiciansPhysicians&apos OfficesPositioning AttributeProductivityPublic HealthRequest for ApplicationsResearchResearch PersonnelResearch PriorityResearch Project GrantsResearch TrainingResidenciesResourcesScholarshipScientistSignal TransductionSocietiesStructureStudy SectionTimeTrainingTraining ProgramsTranslational ResearchUnited States National Institutes of HealthUniversitiesWorkWritingcareercareer developmentclinical trainingclinical translationcoronavirus diseasedisorder preventionearly phase clinical trialexperiencehealth dataimplementation researchimprovedinnovationmedical schoolsmeetingsmultidisciplinarynext generationnovel diagnosticsnovel strategiesnovel therapeutic interventionpediatric departmentpreferencepreventprogramspublic health relevanceresponseskillssuccesstool
中文摘要
摘要/项目摘要
为了应对30年来内科科学家数量的下降,将其归因于长期的临床培训,
教育债务翻了一番或三倍,赠款资金前景不明朗,职业发展轨迹不明确,缺乏
在早期临床培训期间的指导研究机会中,NIH启动了指导研究路径
在驻留R38计划中。住院医师培训是医生培训的关键步骤,通常是通过培训来进行的
不支持医生-科学家发展的计划。受保护的研究存在重大差距
时间,有组织的培训和指导,以及返回诊所后继续研究的支持。初级阶段
多学科杜克大学NHLBI科学家-临床医生-研究人员在
住院医师(Duke SCI-STAR)计划是培养一支多样化的内科-科学家干部队伍,他们将领导
预防、诊断和治疗疾病的新临床模式的开发、实施和评估
在整个生命过程中影响心脏、肺和血液的状态。Duke NHLBI SCI-STAR培训居民
跨3个部门:儿科、内科和外科沿线地区的完整生物医学研究
连续体(基础/转化型、早期临床试验和药代动力学、晚期临床试验
试验和结果),主题是改善生命过程中的健康。该计划将由四个项目组成
培训目标:1)涵盖基础、翻译、临床研究和专业的全面教学
发展;2)发展和完成一个研究项目和个性化的职业发展
计划;3)建立学术活动的跟踪记录;4)获得董事会认证的资格和
继续进行分专业培训。Duke NHLBI SCI-STARR将由以下执行委员会(EC)领导
医学硕士Mai K.ElMallah(儿科)、Scott Palmer(医学)、MHS(医学)和David HarpolJr.
(外科),以及扩大的派驻计划主任和计划协调员组成的EC,利用
由33名多部门、多学科、资金雄厚和经验丰富的教员组成的团队。这
申请申请每年支持三名驻地调查员,每名实习生支持18-
24个月的研究。完成该计划后,这些人员将能够过渡到
研究-密集的奖学金培训,成功地竞争外部资金,以支持一条
独立成为内科科学家,成为领导和指导下一代内科医生
以临床为导向,研究影响心脏、肺和血液的疾病状态的受训人员。取得的成就
该计划的目标将满足以下迫切的医疗需求:1)更多全职学术内科医生-研究人员
和全国医学院的导师;2)小说的创新和临床翻译
在整个生命过程中改善个人健康的战略。
英文摘要
ABSTRACT / PROJECT SUMMARY
In response to a 30-year decline in the number of physician-scientists, attributed to prolonged clinical training,
doubling or tripling of education debt, uncertain grant funding prospects, unclear career trajectories, and a lack
of mentored research opportunities during early clinical training, the NIH started the Mentored ResearchPathway
in Residency R38 program. Residency training, a critical step in physician training, is often carried out by training
programs that do not support physician-scientist development. Significant gaps exist for protected research
time, structured trainingand mentoring, and support to continue researchafter returningto the clinic. The primary
goal of the multidisciplinary Duke NHLBI Scientist-Clinician-Investigator Stimulating access to Research during
Residency (Duke SCI-StARR) program is to train a diverse cadre of physician-scientists who will lead the
development, implementation, and evaluation of new clinical modalities to prevent, diagnose, and treat disease
states affecting the heart, lungs, and blood throughout the life-course. Duke NHLBI SCI-StARR trainS residents
across 3 departments: Pediatrics, Medicine, and Surgery in areas along the full biomedical research
continuum (basic/translational, early phase clinical trials and pharmacokinetics, and late phase clinical
trials and outcomes) with a theme of improving health over the life course. The program will consist of four
training aims: 1) comprehensive didactics covering basic, translational, and clinical research and professional
development; 2) development and completion of a research project and an individualized career development
plan; 3) establishment of a track record of scholarly activity; and 4) eligibility for board certification and
continuation to subspecialty training. Duke NHLBI SCI-StARR will be led by an Executive Committee (EC) of
MPIs Mai K. ElMallah, MD (Pediatrics), Scott Palmer, MD, MHS (Medicine), and David Harpole, Jr., MD
(Surgery), and an Expanded EC of Residency Program Directors and Program Coordinators, capitalizing on a
team of 33 multi-departmental, multi-disciplinary, well-funded, and experienced faculty preceptors. This
application requests support for three Resident-Investigators each year with each trainee to be supported for 18-
24 months of research. Upon completion of the program, these individuals will be capable of transitioning to
research-intense fellowship training, successfully competing for extramural funding to support a path to
independence as physician-scientists, and becoming the next generation of physicians leading and mentoring
trainees in clinically-oriented research of disease states affecting the heart, lungs, and blood. Achievement of
the program's objectives will fulfill urgent medical needs for: 1) more full-time academic physician-researchers
and mentors in medical schools throughout the country and 2) innovations and clinical translation of novel
strategies to improve the health of individuals across the life course.
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DOI:
10.1161/circgen.120.003131
发表时间:
2021-03
期刊:
Circulation. Genomic and precision medicine
影响因子:
--
作者:
[Connell PS, Berkman AM, Souder BM, Pirozzi EJ, Lovin JJ, Rosenfeld JA, Liu P, Tunuguntla H, Allen HD, Denfield SW, Kim JJ, Landstrom AP]
通讯作者:
Landstrom AP
DOI:
10.1111/cge.13968
发表时间:
2021-08
期刊:
Clinical genetics
影响因子:
3.5
作者:
[]
通讯作者:
DOI:
10.1016/j.athoracsur.2020.04.101
发表时间:
2020-11
期刊:
The Annals of thoracic surgery
影响因子:
--
作者:
[Weissler EH, Voigt SL, Raman V, Jawitz O, Doberne J, Anand J, Plichta R, Gaca JG, McCann RL, Hughes GC]
通讯作者:
Hughes GC
DOI:
10.1007/s11886-020-01422-x
发表时间:
2020-10-10
期刊:
Current cardiology reports
影响因子:
3.7
作者:
[Regan JA, Shah SH]
通讯作者:
Shah SH
Painful, reappearing eruption in a medically complex 4-year-old.
一名病情复杂的 4 岁儿童再次出现疼痛性皮疹。
DOI:
10.1136/bcr-2020-239310
发表时间:
2021
期刊:
BMJ case reports
影响因子:
0.9
作者:
[Sooy,Meredith, Randell,RachelL, Tchapyjnikov,Dmitry, Werner,Klaus, Nazareth-Pidgeon,Kristina]
通讯作者:
Nazareth-Pidgeon,Kristina
共 16 条
Respiratory Dysfunction in an Optineurin knock out ALS mouse model
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批准号:9978360
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项目类别:
-
资助金额:$44.28万
-
财政年份:2020
-
负责人:Mai ElMallah
-
依托单位:
Targeted Therapy for Pompe Disease
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批准号:10621268
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项目类别:
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资助金额:$34.54万
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财政年份:2019
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负责人:Mai ElMallah
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依托单位:
Targeted Therapy for Pompe Disease
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批准号:10202684
-
项目类别:
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资助金额:$34.54万
-
财政年份:2019
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负责人:Mai ElMallah
-
依托单位:
Targeted Therapy for Pompe Disease
-
批准号:10017695
-
项目类别:
-
资助金额:$34.84万
-
财政年份:2019
-
负责人:Mai ElMallah
-
依托单位:
Targeted Therapy for Pompe Disease
-
批准号:10402842
-
项目类别:
-
资助金额:$34.54万
-
财政年份:2019
-
负责人:Mai ElMallah
-
依托单位:
Duke Resident Physician-Scientist Program- NHLBI
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批准号:10202710
-
项目类别:
-
资助金额:$33.94万
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财政年份:2018
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负责人:Mai ElMallah
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依托单位:
Gene Therapy for Upper Airway and Respiratory Insufficiency in an ALS Mouse Model
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批准号:9581552
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项目类别:
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资助金额:$20.94万
-
财政年份:2016
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负责人:Mai ElMallah
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依托单位:
Gene Therapy for Upper Airway and Respiratory Insufficiency in an ALS Mouse Model
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批准号:9166838
-
项目类别:
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资助金额:$23.78万
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财政年份:2016
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负责人:Mai ElMallah
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依托单位:
Novel Approaches for Correcting Respiratory Insufficiency in Pompe Disease
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批准号:8912059
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项目类别:
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资助金额:$10.77万
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财政年份:2014
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负责人:Mai ElMallah
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依托单位:
Novel Approaches for Correcting Respiratory Insufficiency in Pompe Disease
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批准号:9262981
-
项目类别:
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资助金额:$3.77万
-
财政年份:2014
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负责人:Mai ElMallah
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依托单位:
Novel Approaches for Correcting Respiratory Insufficiency in Pompe Disease
-
批准号:9600122
-
项目类别:
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资助金额:$12.45万
-
财政年份:2014
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负责人:Mai ElMallah
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依托单位:
Novel Approaches for Correcting Respiratory Insufficiency in Pompe Disease
-
批准号:8700662
-
项目类别:
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资助金额:$1.4万
-
财政年份:2014
-
负责人:Mai ElMallah
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依托单位:
海外基金