Duke Resident Physician-Scientist Program- NHLBI

医生-科学家劳动力一直是许多重大发现的重要推动力， 在过去的二十年里，医疗和保健。然而，临床科学家受训人员的管道已经在 由于临床培训的复杂性和要求，医学院毕业后债务不断增加， 国家卫生研究院的工资线下降，重要的是，在临床培训期间缺乏研究指导。后 四年或更长时间的住院医师培训，几乎没有时间或支持研究工作，有许多 研究型受训者启动或重新启动研究的障碍。这是一个重大差距， 培养准备在其职业生涯中将研究转化为临床竞技场的医生科学家。 多学科杜克科学家-临床医生-研究者的主要目标是促进研究的可及性 在住院期间（杜克SCI-StARR）计划是在生物医学的各个方面培训医生科学家 研究，以培养调查人员谁将领导开发，实施和评估 预防、诊断和治疗影响心脏、肺和血液的疾病状态的新临床模式。 杜克SCI-StARR将在沿着地区培训3个部门的居民：儿科，内科和外科 完整的生物医学研究连续体（基础/转化，早期临床试验和 药代动力学和后期临床试验和结果），主题是改善健康， 生命历程该方案将包括四个培训目标：1）综合教学法，涵盖基础， 翻译，临床研究和专业发展; 2）开发和完成一个 研究项目和个性化的职业发展计划; 3）建立学术记录 活动;和4）资格委员会认证和继续亚专业培训。杜克科学星将 由MPI执行委员会（EC）领导Sallie Permar，MD，PhD（儿科），Scott Palmer，MD，MHS （医学）和大卫哈波尔，医学博士（外科），和一个SCI-StARR副项目主任从每个 部门，沿着扩大的EC居住计划主任和计划协调员， 利用23个多部门，多学科，资金充足，经验丰富的教师团队 导师本申请要求每年为三名驻地研究员提供支持，每名受训人员 支持18-24个月的研究。在该计划完成后，这些人将能够 过渡到研究密集型奖学金培训，成功地竞争校外资金， 支持作为医生-科学家独立的道路，并成为下一代医生 领导和指导学员在临床为导向的研究疾病状态影响心脏，肺， 血该计划的目标的实现将满足迫切的医疗需求：1）更多的全职学术 全国各地医学院的医生研究人员和导师，2）创新和临床 翻译新的战略，以改善个人的健康在整个生命过程中。

The physician-scientist workforce has been an important driver for many of the substantial discoveries in medicine and health-care over the last two decades. Yet, the pipeline of clinician-scientist trainees has been in decline, fueled by complexity and requirements of clinical training, mounting debt after medical school, declining NIH paylines, and importantly, lack of access to research mentorship during clinical training. After four or more years of residency training with little time or support for research endeavors, there are many hurdles for research-oriented trainees to initiate or re-initiate research. This represents a major gap in the development of physician-scientists prepared to translate research into the clinical arena during their careers. The primary goal of the multidisciplinary Duke Scientist-Clinician-Investigator Stimulating access to Research during Residency (Duke SCI-StARR) program is to train physician-scientists in all aspects of biomedical research in order to cultivate investigators who will lead the development, implementation, and evaluation of new clinical modalities to prevent, diagnose, and treat disease states affecting the heart, lungs, and blood. Duke SCI-StARR will train residents across 3 departments: Pediatrics, Medicine, and Surgery in areas along the full biomedical research continuum (basic/translational, early phase clinical trials and pharmacokinetics, and late phase clinical trials and outcomes) with a theme of improving health over the life course. The program will consist of four training aims: 1) comprehensive didactics covering basic, translational, and clinical research and professional development; 2) development and completion of a research project and an individualized career development plan; 3) establishment of a track record of scholarly activity; and 4) eligibility for board certification and continuation to subspecialty training. Duke SCI-StARR will be led by an Executive Committee (EC) of MPIs Sallie Permar, MD, PhD (Pediatrics), Scott Palmer, MD, MHS (Medicine), and David Harpole, Jr, MD (Surgery), and a SCI-StARR Associate Program Director from each department, along with an Expanded EC of Residency Program Directors and Program Coordinators, capitalizing on a team of 23 multi-departmental, multi-disciplinary, well-funded, and experienced faculty preceptors. This application requests support for three Resident-Investigators each year with each trainee to be supported for 18-24 months of research. Upon completion of the program, these individuals will be capable of transitioning to research-intense fellowship training, successfully competing for extramural funding to support a path to independence as physician-scientists, and becoming the next generation of physicians leading and mentoring trainees in clinically-oriented research of disease states affecting the heart, lungs, and blood. Acheivement of the program's objectives will fulfill urgent medical needs for: 1) more full-time academic physician-researchers and mentors in medical schools throughout the country and 2) innovations and clinical translation of novel strategies to improve the health of individuals across the life course.