Duke Resident Physician-Scientist Program- NHLBI

杜克大学住院医生科学家计划 - NHLBI

• 批准号: 10202710
• 负责人: Mai ElMallah
• 金额: $ 33.94万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10202710
• 关键词: Achievement; Address; Affect; Applications Grants; Area; Award; Basic Science; Biomedical Research; Blood; Board Certification; Clinic; Clinical; Clinical Research; Clinical Trials; Communication; Country; Data Science; Development; Development Plans; Diagnosis; Disease; Doctor of Philosophy; Drug Kinetics; Educational workshop; Eligibility Determination; Ensure; Evaluation; Extramural Activities; Faculty; Fellowship; Fostering; Funding; Goals; Grant; Health; Healthcare; Heart; Human; Individual; Institutes; Journals; Laboratory Research; Lead; Life Cycle Stages; Lung; Manuscripts; Medical; Medicine; Mentors; Mentorship; Methods; Mission; Modality; Modernization; National Heart, Lung, and Blood Institute; Operative Surgical Procedures; Outcome; Pediatrics; Peer Review; Phase; Physicians; Positioning Attribute; Request for Applications; Research; Research Personnel; Research Priority; Research Project Grants; Research Support; Research Training; Residencies; Scholarship; Scientist; Structure; Study Section; Time; Training; Training Programs; Training and Education; Translating; Translational Research; United States National Institutes of Health; Universities; Wages; Work; Writing; career; career development; clinical translation; disorder prevention; early phase clinical trial; experience; health data; implementation research; improved; innovation; medical schools; medical specialties; meetings; multidisciplinary; next generation; novel diagnostics; novel strategies; novel therapeutic intervention; pediatric department; preference; prevent; programs; success

The physician-scientist workforce has been an important driver for many of the substantial discoveries in medicine and health-care over the last two decades. Yet, the pipeline of clinician-scientist trainees has been in decline, fueled by complexity and requirements of clinical training, mounting debt after medical school, declining NIH paylines, and importantly, lack of access to research mentorship during clinical training. After four or more years of residency training with little time or support for research endeavors, there are many hurdles for research-oriented trainees to initiate or re-initiate research. This represents a major gap in the development of physician-scientists prepared to translate research into the clinical arena during their careers. The primary goal of the multidisciplinary Duke Scientist-Clinician-Investigator Stimulating access to Research during Residency (Duke SCI-StARR) program is to train physician-scientists in all aspects of biomedical research in order to cultivate investigators who will lead the development, implementation, and evaluation of new clinical modalities to prevent, diagnose, and treat disease states affecting the heart, lungs, and blood. Duke SCI-StARR will train residents across 3 departments: Pediatrics, Medicine, and Surgery in areas along the full biomedical research continuum (basic/translational, early phase clinical trials and pharmacokinetics, and late phase clinical trials and outcomes) with a theme of improving health over the life course. The program will consist of four training aims: 1) comprehensive didactics covering basic, translational, and clinical research and professional development; 2) development and completion of a research project and an individualized career development plan; 3) establishment of a track record of scholarly activity; and 4) eligibility for board certification and continuation to subspecialty training. Duke SCI-StARR will be led by an Executive Committee (EC) of MPIs Sallie Permar, MD, PhD (Pediatrics), Scott Palmer, MD, MHS (Medicine), and David Harpole, Jr, MD (Surgery), and a SCI-StARR Associate Program Director from each department, along with an Expanded EC of Residency Program Directors and Program Coordinators, capitalizing on a team of 23 multi-departmental, multi-disciplinary, well-funded, and experienced faculty preceptors. This application requests support for three Resident-Investigators each year with each trainee to be supported for 18-24 months of research. Upon completion of the program, these individuals will be capable of transitioning to research-intense fellowship training, successfully competing for extramural funding to support a path to independence as physician-scientists, and becoming the next generation of physicians leading and mentoring trainees in clinically-oriented research of disease states affecting the heart, lungs, and blood. Acheivement of the program's objectives will fulfill urgent medical needs for: 1) more full-time academic physician-researchers and mentors in medical schools throughout the country and 2) innovations and clinical translation of novel strategies to improve the health of individuals across the life course.

医生-科学家队伍一直是许多重大发现的重要驱动力 在过去的二十年里，医学和医疗保健。然而，临床医生-科学家实习生的管道已经进入 由于临床培训的复杂性和要求，医学院毕业后债务不断增加， NIH支付线的下降，以及重要的是，在临床培训期间缺乏研究指导。之后 四年或更长时间的住院医师培训，几乎没有时间或对研究工作的支持，有很多 面向研究的受训人员发起或重新发起研究的障碍。这是一个重大的差距， 内科医生的发展--科学家准备在他们的职业生涯中将研究成果转化为临床领域。 多学科杜克大学科学家-临床医生-研究人员激励研究途径的主要目标 驻院期间(杜克大学SCI-STARR)计划是在生物医学的各个方面培训内科科学家 研究，以培养将领导开发、实施和评估的调查人员 预防、诊断和治疗影响心脏、肺和血液的疾病状态的新临床模式。 杜克SCI-STAR将培训三个部门的住院医生：儿科、内科和外科，在沿线地区 完整的生物医学研究连续体(基础/转换、早期临床试验和 药代动力学，以及后期临床试验和结果)，主题是改善健康 生命历程。该计划将包括四个培训目标：1)全面的教学，涵盖基础， 翻译、临床研究和专业发展；2)开发和完成 研究项目和个性化的职业发展计划；3)建立学术记录 活动；以及4)获得董事会认证和继续进行分专业培训的资格。史西-斯塔尔公爵将 由MPIS执行委员会(EC)领导，Sallie Permar，医学博士，博士(儿科)，Scott Palmer，医学博士，MHS (医学)，和David HarpolJr，MD(外科)，以及SCI-Starr副项目主任 部门，以及扩大的派驻方案主任和方案协调员组成的EC， 利用一支由23名多部门、多学科、资金雄厚和经验丰富的教师组成的团队 训诫。此应用程序要求每年为三名驻地调查员提供支持，每名实习生 支持18-24个月的研究。计划完成后，这些人将有能力 过渡到研究密集型奖学金培训，成功竞争外部资金以 支持作为内科科学家独立的道路，并成为下一代内科医生 在影响心脏、肺和肺的疾病状态的临床导向研究中，领导和指导受训人员 血。该计划目标的实现将满足以下迫切的医疗需求：1)更多全日制学术 全国各地医学院的医生-研究人员和导师以及2)创新和临床 翻译新颖的策略，以改善个人在整个生命过程中的健康。