Children's Hospital Los Angeles Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)

洛杉矶儿童医院站点联盟 - HIV/艾滋病干预青少年医学试验网络 (ATN) 运营和合作中心(UM2 临床试验可选)

基本信息

  • 批准号:
    10599558
  • 负责人:
  • 金额:
    $ 39.69万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-09-22 至 2029-06-30
  • 项目状态:
    未结题

项目摘要

ABSTRACT Children's Hospital Los Angeles (CHLA) Children's Hospital Los Angeles (CHLA) is proposing to be the lead site for the Los Angeles Consortium. The primary aim is to collaborate with Westat as the Adolescent Trials Network (ATN) Operations and Collaborations Center (OCC) to successfully plan and implement ATN clinical research studies to meet the priority areas as outlined in SLC RFA-HD-23-020. CHLA will leverage the strength of the Connect to Protect Los Angeles (C2PLA) Coalition to lead a Research Advisory Committee of community, clinical, and academic partners to: 1. Conduct the Research Projects identified by the ATN Executive and Scientific Leadership Committees; 2. Participate in the development of trials using our community, academic, and clinical partners in conjunction with the ATN Scientific Core to meet the needs of adolescents and young adults (AYA) at- risk for or living with HIV; 3. Contribute to innovative strategies within ATN V regarding successful recruitment and enrollment of participants through established collaborations among clinics, academic universities, community-based organizations, health departments, and other partners; 4. Provide sites with local laboratory capacity and pharmacy support; and 5. Establish a leadership model with meaningful and sustained community engagement efforts to ensure that research studies reflect where AYA are accessing prevention and care services. Our proposed consortium will initially include nine partners who will bring their strength and diversity to a site consortium that will include clinical, academic, government, community, and other partnerships. We have four clinical sites that provide care to AYA living with HIV and at risk for HIV including mostly LGBTQ AYA of color and two partners that currently house large databases of AYA living with HIV and at risk for HIV: ATN CARES at UCLA and the NIDA UO1-funded Healthy Young Men/A Trans Youth of Color Study cohort at CHLA. We have initially targeted four community-based organizations and the County of Los Angeles Department of Public Health Division of HIV and STD Programs. Representatives of these groups and our AYA community advisory boards will form an innovative leadership structure that is representative of our communities and can provide leadership through protocol review, new protocol development, and guidance on recruitment and retention. Based on decades of experience with clinical services and research with AYA, our proposed Los Angeles ATN V Consortium is well suited to join the OCC and other city consortia. CHLA has exceptional access to AYA likely needed in future clinical trials, decades of ongoing community partnerships, and an outstanding track record for recruiting and retaining hard to reach AYA into clinical trials, including complex medical interventions requiring investigational new drugs (IND), research laboratories, and pharmacy services.
洛杉矶儿童医院(CHLA) 洛杉矶儿童医院(CHLA)正在提议成为洛杉矶财团的牵头地点。这个 主要目标是与Westat合作,作为青少年试验网络(ATN)运营和 协作中心(OCC)成功规划和实施ATN临床研究,以满足 SLC RFA-HD-23-020中概述的优先领域。CHLA将利用Connect的力量来保护 洛杉矶(C2解放军)联盟将领导社区、临床和学术研究咨询委员会 合作伙伴: 1.开展ATN执行委员会和科学领导委员会确定的研究项目; 2.使用我们的社区、学术和临床合作伙伴参与试验的开发 与ATN科学核心合作,以满足青少年和青壮年在以下方面的需求- 艾滋病毒风险或艾滋病毒携带者; 3.促进ATN V内部关于成功招募和登记以下人员的创新战略 参与者通过诊所、学术大学、基于社区的已建立的合作 组织、卫生部门和其他合作伙伴; 4.提供具有本地实验室能力和药房支持的地点;以及 5.通过有意义和持续的社区参与努力建立领导模式,以确保 这项研究反映了Aya在哪里获得预防和护理服务。 我们提议的财团最初将包括9个合作伙伴,他们将把自己的优势和多样性带到一个地点 将包括临床、学术、政府、社区和其他合作伙伴关系的联盟。我们有四个 为艾滋病毒携带者和有艾滋病毒风险的Aya提供护理的临床网站,主要包括LGBTQ Aya of Color 和两个合作伙伴,目前存储着Aya艾滋病毒携带者和艾滋病毒风险的大型数据库:ATN CARE 加州大学洛杉矶分校和NIDA UO1资助的健康青年男性/跨肤色青年研究队列。我们 最初的目标是四个社区组织和洛杉矶县 艾滋病毒和性传播疾病项目公共卫生司。这些团体和我们阿雅社区的代表 顾问委员会将形成一个代表我们社区的创新领导结构,并能够 通过协议审查、新协议开发以及招聘和指导提供领导 留存。基于数十年来对Aya的临床服务和研究经验,我们建议的LOS 洛杉矶ATN V财团非常适合加入OCC和其他城市财团。CHLA拥有非凡的 在未来的临床试验中可能需要获得Aya,数十年来正在进行的社区合作伙伴关系,以及 在招募和留住难以接触到AYA的临床试验方面有出色的记录,包括复杂的 需要研究新药(IND)、研究实验室和药房服务的医疗干预。

项目成果

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MARVIN E BELZER其他文献

MARVIN E BELZER的其他文献

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{{ truncateString('MARVIN E BELZER', 18)}}的其他基金

Children's Hospital Los Angeles Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Trial Optional)
洛杉矶儿童医院站点联盟 - HIV/艾滋病干预青少年医学试验网络 (ATN) 运营和合作中心(UM2 临床试验可选)
  • 批准号:
    10709604
  • 财政年份:
    2022
  • 资助金额:
    $ 39.69万
  • 项目类别:
Digital, Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in Young Transgender Women
LifeSkills Mobile 数字化、有限互动功效试验可降低年轻跨性别女性的艾滋病毒发病率
  • 批准号:
    10598468
  • 财政年份:
    2021
  • 资助金额:
    $ 39.69万
  • 项目类别:
Digital, Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in Young Transgender Women
LifeSkills Mobile 数字化、有限互动功效试验可降低年轻跨性别女性的艾滋病毒发病率
  • 批准号:
    10369005
  • 财政年份:
    2021
  • 资助金额:
    $ 39.69万
  • 项目类别:
Youth Services Navigation Intervention for HIV+ adolescents and young adults being released from incarceration: A randomized control trial
针对从监狱释放的艾滋病毒青少年和年轻人的青年服务导航干预:一项随机对照试验
  • 批准号:
    9890791
  • 财政年份:
    2017
  • 资助金额:
    $ 39.69万
  • 项目类别:
Youth Services Navigation Intervention for HIV+ adolescents and young adults being released from incarceration: A randomized control trial
针对出狱的艾滋病毒青少年和年轻人的青年服务导航干预:一项随机对照试验
  • 批准号:
    9540937
  • 财政年份:
    2017
  • 资助金额:
    $ 39.69万
  • 项目类别:
PK STUDY OF ANTIRETROVIRAL THERAPY REGIMENS CONTAINING TENFOVIR AND ATAZANIVIR
含替福韦和阿扎尼韦的抗逆转录病毒治疗方案的药代动力学研究
  • 批准号:
    7716626
  • 财政年份:
    2008
  • 资助金额:
    $ 39.69万
  • 项目类别:
PK STUDY OF ANTIRETROVIRAL THERAPY REGIMENS CONTAINING TENFOVIR AND ATAZANIVIR
含替福韦和阿扎尼韦的抗逆转录病毒治疗方案的药代动力学研究
  • 批准号:
    7603853
  • 财政年份:
    2006
  • 资助金额:
    $ 39.69万
  • 项目类别:
Adolescent Medicine Trials Network for HIV/AIDS Interve*
艾滋病毒/艾滋病干预青少年医学试验网络*
  • 批准号:
    7195770
  • 财政年份:
    2001
  • 资助金额:
    $ 39.69万
  • 项目类别:
Adolescent Medicine Trials Network for HIV/AIDS Interve*
艾滋病毒/艾滋病干预青少年医学试验网络*
  • 批准号:
    7414388
  • 财政年份:
    2001
  • 资助金额:
    $ 39.69万
  • 项目类别:
ADOLESCENT MEDICINE TRIAL NETWORK FOR HIV/AIDS
艾滋病毒/艾滋病青少年药物试验网络
  • 批准号:
    6530562
  • 财政年份:
    2001
  • 资助金额:
    $ 39.69万
  • 项目类别:

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