HEALing Communities Study Data Coordinating Center

项目摘要/摘要 美国继续努力应对阿片类药物过量危机，这一危机导致严重且不断增加的 造成发病率和死亡率的损失。循证实践(EBP)是为解决这一持续的危机而发展起来的 包括阿片类药物过量教育和纳洛酮分配方案；处方药监测方案 阿片类药物处方指南；FDA批准的治疗阿片类药物使用障碍的药物；开始治疗 和保留干预措施；以及恢复支助服务。然而，这些EBP并没有充分渗透到 阿片类药物滥用和阿片类药物使用障碍普遍存在的社区环境，也没有被当地居民利用 利益相关者，包括在社区生活、工作和使用毒品的人。 康复社区研究(HCS)设计了康复社区(Cth)干预， 社区参与、数据驱动的规划进程，以迅速减少#年阿片类药物过量死亡 美国四个州的67个社区：肯塔基州、马萨诸塞州、纽约州和俄亥俄州。Cth干预 包括三个组成部分：(1)社区参与；(2)阿片类药物过量减少连续不断 护理方法(ORCCA)；以及(3)一套宣传活动，以减少耻辱并推动对 EBPS。 作为数据协调中心(DCC)，RTI将翻译和传播符合以下条件的干预产品 根据特定受众的信息需求、健康素养水平和沟通偏好进行定制。 我们的经验丰富的团队参与了HCS家长研究，将采用以最终用户为中心的方法来推动 本补编项下的传播工作有两个具体目标。我们将加快HCS的翻译 通过采用社区参与的研究传播框架(目标1)将研究转化为实践，我们 将与HCS利益相关者和外部专家合作，基于社区创建传播产品 Cth干预和ORCCA的参与组成部分(目标2)。 DCC具有克服与开发和执行具有凝聚力的 提高合作研究的科学和公众能见度的传播战略。我们是由 多名首席调查员-Emmanuel Oga博士、LaShawn Glasgow博士和Gary Zarkin博士-他们是 有经验的多站点研究负责人和药物滥用、计划管理和 凝聚共识。更广泛的核心领导团队带来强大的科学和实施科学 技能与对阿片类药物滥用和成瘾的预防科学的深刻理解交织在一起。目标明确 并迅速传播社区参与的经验教训，这将提供实践- 以指导社区如何应对当地的阿片类药物危机为基础。

Project Summary/Abstract The United States continues to grapple with an opioid overdose crisis that exacts a heavy, and increasing, toll on morbidity and mortality. Evidence-based practices (EBPs) developed to address this ongoing crisis include opioid overdose education and naloxone distribution programs; prescription drug monitoring programs and guidelines for opioid prescribing; FDA-approved medications for opioid use disorder; treatment initiation and retention interventions; and recovery support services. However, these EBPs do not sufficiently penetrate community settings where opioid misuse and opioid use disorder are prevalent, nor are they utilized by local stakeholders, including people who live, work, and use drugs in communities. The HEALing Communities Study (HCS) designed the Communities That HEAL (CTH) intervention, a community-engaged, data-driven planning process to rapidly achieve reductions in opioid overdose deaths in 67 communities across four U.S. states: Kentucky, Massachusetts, New York, and Ohio. The CTH intervention includes three components: (1) community engagement; (2) the Opioid-overdose Reduction Continuum of Care Approach (ORCCA); and (3) a set of communication campaigns to reduce stigma and drive demand for EBPs. As the Data Coordination Center (DCC), RTI will translate and disseminate intervention products that are customized to specific audience information needs, health literacy levels, and preferences for communication. Our experienced team, engaged with the HCS parent study, will employ end user–focused methods to drive dissemination efforts under this supplement through two specific aims. We will accelerate translation of HCS research to practice by adapting the Community‐Engaged Research Dissemination framework (Aim 1), and we will engage HCS stakeholders and external experts to create dissemination products based on the community engagement components of the CTH intervention and the ORCCA (Aim 2). The DCC has experience overcoming the challenges associated with developing and executing a cohesive dissemination strategy that elevates the scientific and public visibility of a research collaborative. We are led by multiple Principal Investigators—Drs. Emmanuel Oga, LaShawn Glasgow, and Gary Zarkin—who are experienced leaders of multisite studies and experts in substance abuse, program management, and consensus building. The broader team of Core Leaders brings robust scientific and implementation science skills interwoven with a deep understanding of prevention science of opioid misuse and addiction. Targeted and rapid dissemination of community engagement lessons from the CTH intervention will provide practice- based guidance to communities on how to respond to their local opioid crisis.