HEALing Communities Study Data Coordinating Center

项目总结/摘要 美国继续努力应对阿片类药物过量的危机，这一危机带来了沉重的，而且越来越多的， 发病率和死亡率。为应对这一持续危机而制定的循证实践 包括阿片类药物过量教育和纳洛酮分发方案;处方药监测方案 阿片类药物处方和指南; FDA批准的阿片类药物使用障碍药物;治疗开始 和保留干预措施;以及恢复支助服务。然而，这些EBP不能充分渗透 阿片类药物滥用和阿片类药物使用障碍普遍存在的社区环境， 利益相关者，包括在社区中生活、工作和使用毒品的人。 愈合社区研究（HCS）设计了社区愈合（CTH）干预， 社区参与，数据驱动的规划过程，以迅速实现减少阿片类药物过量死亡， 美国四个州的67个社区：肯塔基州、马萨诸塞州、纽约和俄亥俄州。CTH干预 包括三个组成部分：（1）社区参与;（2）阿片类药物过量减少连续 护理方法（ORCCA）;以及（3）一系列宣传活动，以减少耻辱感并推动对 EBP。 作为数据协调中心（DCC），RTI将翻译和传播干预产品， 根据特定受众的信息需求、健康素养水平和沟通偏好进行定制。 我们经验丰富的团队参与了HCS母公司研究，将采用以最终用户为中心的方法来推动 该补编通过两个具体目标开展传播工作。我们将加快HCS的翻译 通过调整社区研究传播框架（目标1），研究实践，我们 将与HCS利益相关者和外部专家合作，以创建基于社区的传播产品 CTH干预和ORCCA的参与组成部分（目标2）。 DCC具有克服与开发和执行内聚 传播战略，提高科学和公共知名度的研究合作。我们的领导者是 多位首席研究员--伊曼纽尔·奥加博士、拉肖恩·格拉斯哥博士和加里·扎金博士--他们是 多中心研究的经验丰富的领导者和药物滥用，项目管理， 建立共识。更广泛的核心领导团队带来了强大的科学和实施科学 技能与对阿片类药物滥用和成瘾预防科学的深刻理解交织在一起。针对性 从CTH干预中迅速传播社区参与经验教训将提供实践- 为社区提供关于如何应对当地阿片类药物危机的指导。

Project Summary/Abstract The United States continues to grapple with an opioid overdose crisis that exacts a heavy, and increasing, toll on morbidity and mortality. Evidence-based practices (EBPs) developed to address this ongoing crisis include opioid overdose education and naloxone distribution programs; prescription drug monitoring programs and guidelines for opioid prescribing; FDA-approved medications for opioid use disorder; treatment initiation and retention interventions; and recovery support services. However, these EBPs do not sufficiently penetrate community settings where opioid misuse and opioid use disorder are prevalent, nor are they utilized by local stakeholders, including people who live, work, and use drugs in communities. The HEALing Communities Study (HCS) designed the Communities That HEAL (CTH) intervention, a community-engaged, data-driven planning process to rapidly achieve reductions in opioid overdose deaths in 67 communities across four U.S. states: Kentucky, Massachusetts, New York, and Ohio. The CTH intervention includes three components: (1) community engagement; (2) the Opioid-overdose Reduction Continuum of Care Approach (ORCCA); and (3) a set of communication campaigns to reduce stigma and drive demand for EBPs. As the Data Coordination Center (DCC), RTI will translate and disseminate intervention products that are customized to specific audience information needs, health literacy levels, and preferences for communication. Our experienced team, engaged with the HCS parent study, will employ end user–focused methods to drive dissemination efforts under this supplement through two specific aims. We will accelerate translation of HCS research to practice by adapting the Community‐Engaged Research Dissemination framework (Aim 1), and we will engage HCS stakeholders and external experts to create dissemination products based on the community engagement components of the CTH intervention and the ORCCA (Aim 2). The DCC has experience overcoming the challenges associated with developing and executing a cohesive dissemination strategy that elevates the scientific and public visibility of a research collaborative. We are led by multiple Principal Investigators—Drs. Emmanuel Oga, LaShawn Glasgow, and Gary Zarkin—who are experienced leaders of multisite studies and experts in substance abuse, program management, and consensus building. The broader team of Core Leaders brings robust scientific and implementation science skills interwoven with a deep understanding of prevention science of opioid misuse and addiction. Targeted and rapid dissemination of community engagement lessons from the CTH intervention will provide practice- based guidance to communities on how to respond to their local opioid crisis.