Optimizing Individualized and Adaptive mHealth Interventions via Control Systems Engineering Methods

项目摘要/摘要。尽管之前的研究已经确认了以人为中心的 开发数字行为改变干预(DBCI)的设计方法，它考虑了 目标人群的数字素养和健康状况、当前商业上可用的mHealth应用程序 不符合西班牙裔/拉丁裔3-7的语言、必备知识、激励和独特的文化需求。 此外，简单地采用英语的协议，较高的数字素养DBCI，并翻译 尚未发现与用户首选语言匹配的材料对DBCI应用程序的使用产生积极影响，或者 订婚7.家长R01正在大圣地亚哥进行，那里的人口估计 是34%的西班牙裔/拉丁裔，并以招生为目标，招募该地区具有代表性的样本16。因此， 家长赠款提供了一个极好的机会来研究PA的实施和参与 将重点放在不同的样本人群中，包括一大批西班牙裔/拉丁裔参与者。 这项研究将使用多方法(定性和定量)来提供深入的理解 与西班牙裔/拉丁裔中的DBCI参与度相关的独特因素。这些结果将直接告知 设计和优化下一代具有文化相关性和参与性的DBCI 控制优化试验(COT)方法，以开发个性化和永久适应的干预措施。 这一多样性副刊将支持德拉托雷先生开发一个适应文化的版本 你的行动干预，专门针对西班牙裔/拉美裔家庭。这一目标产生了多种协同效益。 包括：1)对于De La Torre先生来说，建议的工作将是非常好的，使他能够申请一个可能的 NIH颁发的K-奖，以支持他转变为致力于发展的教职员工 在他的职业生涯中专门为拉美裔/拉丁裔人口服务并促进健康公平的DBCI，2) 西班牙裔/拉美裔社区，多样性补充将使严格的文化定制，通过 补充AIMS，以及3)对于亲本R01，这种多样性补充将使方法和 要使用和改进的方法，具体侧重于减少卫生不平等和不平等；因此， 多样性补充为亲本R01提供了一种机制，以更有意义地促进进步 卫生公平，通过提供一条具体的、可操作的途径，制定一种经过翻译和文化上的 适当延长YourMove干预措施。本补编建议的活动仍在 父母奖励的原始范围，并将增加从父母那里获得的知识的影响 研究，特别是针对西班牙裔/拉丁裔研究参与者。

Project Summary/Abstract. Although previous research has identified the importance of a human-centered design approach to the development of digital behavior change interventions (DBCIs) which considers the digital literacy and health status of the target population, current commercially available mHealth applications do not meet the language, prerequisite knowledge, incentive, and unique cultural needs of Hispanic/Latinos3-7. Furthermore, simply taking the protocol of English language, higher digital literacy DBCIs, and translating the material to match the user’s preferred language has not been found to positively influence DBCI app usage or engagment7. The parent R01 is being conducted in Greater San Diego, where the population is estimated to be 34% Hispanic/Latino, and targets enrollment to recruit a representative sample of this region16. Therefore, the parent grant provides an excellent opportunity to study the implementation of, and engagement with, a PA focused DBCI among a diverse sample population including a significant group of Hispanic/Latino participants. This study will use a multimethod approach (qualitative and quantitative) to provide an in-depth understanding of the unique factors related to DBCI engagement among Hispanic/Latinos. These results will directly inform the design and optimization of the next generation of culturally relevant and engaging DBCIs based on the control optimization trial (COT) approach to developing personalized and perpetually adapting interventions. This diversity supplement will support Mr. De La Torre in developing a culturally adapted version of the YourMove intervention, specific for Hispanic/Latino families. This target produces multiple synergistic benefits including: 1) for Mr. De La Torre, the proposed work would be excellent for enabling him to apply for a possible K-award from the NIH, to support his transition into becoming a faculty member committed to developing DBCIs that specifically serve Hispanic/Latino populations in his career and to advance health equity, 2) for Hispanic/Latino communities, the diversity supplement will enable the rigorous cultural tailoring, through the supplements aims, and 3) for the parent R01, this diversity supplement will enable the methods and approaches to be used and refined, with a specific focus on reducing health inequities and disparities; thus, the diversity supplement provides a mechanism for the parent R01 to contribute more meaningfully to advancing health equity, by providing a concrete, actionable pathway for developing a translated and culturally appropriate extension of the YourMove intervention. The activities proposed in this supplement remain within the original scope of the parent award and will increase the impact of the knowledge gained from the parent study, particularly for Hispanic/Latino study participants.