2023 Glial Biology: Functional Interactions Among Glia and Neurons Gordon Research Conference and Gordon Research Seminar

摘要 戈登神经胶质生物学研究会议题为神经胶质网络：细胞生物学、生理学和可塑性 2023年在加利福尼亚州文图拉主办其第10次会议。这次会议汇聚了一群不同的老牌 来自世界各地的研究人员和年轻实习生，被广泛认为是致力于 神经胶质细胞在健康和疾病中的主题。本次GRC的首要目标是讨论关注以下问题的前沿研究 神经胶质细胞发育，神经胶质细胞和健康神经系统中其他类型细胞之间的功能相互作用，以及 神经胶质细胞在神经系统疾病和其他疾病中的作用。2023年会议将强调 关于神经胶质细胞亚型、神经胶质细胞和神经胶质细胞之间细胞、生理和分子相互作用的最新研究进展 神经元、神经胶质细胞和非神经细胞(如免疫系统、血管系统和其他外周屏障)。通过我们的 为了招募创新的演讲者，这次会议将突出最先进的技术，这些技术有可能 极大地扩展了选择性可视化和操作不同胶质细胞类型的能力，以更深入地了解 神经胶质细胞在不同环境中的不同角色。会议将主持45位演讲者的演讲，由15位发言者主持 讨论领导者，代表有影响力的知名科学家和刚刚开始的年轻研究人员 在他们的独立研究事业上。61%的计划演讲者是女性，超过30%的演讲者是女性 年轻的研究人员在建立自己的实验室后的五年内。82%的人已经接受(并在 48小时)，突出了对这次会议的热情。值得注意的是，两位老牌科学家将领导一场及时而重要的 题为创造包容的实验室环境：防止和解决骚扰问题的讨论会(《动力一小时》) 和歧视“。正在积极征求代表人数不足的少数群体的参与，并将由 可用资金，并纳入所有群体的调查员和受训人员，包括任职人数不足的少数群体 和残疾人，将是重中之重。NIH对这笔赠款的支持对于最大限度地提高受训人员的参与度至关重要，因为 它不仅资助GRC，还资助由学员领导的关于胶质生物学的戈登研究研讨会(GRS)，该研讨会将主办其 就在GRC之前的第四次会议。GRS为年轻科学家(研究生和博士后)提供了机会 在现场分享想法，主持主旨演讲，并通过平台或海报演示来展示他们正在进行的工作 向彼此以及GRC主席和主旨发言人致敬。在GRC和GRS中，指定的会议将集中在 脑内神经胶质细胞在神经回路和代谢支持中的发育和功能 更广阔的神经系统。传播尖端研究成果和广泛的培训机会 通过这次会议，初级科学家与NIH和NINDS的总体任务高度相关。

ABSTRACT The Gordon Research Conference on Glial Biology entitled Glial networking: Cell biology, physiology and plasticity will host its 10th meeting in 2023 in Ventura, California. This conference brings together a diverse group of established investigators and young trainees from around the world and is widely considered the preeminent forum devoted to the topic of glial cells in health and disease. The overarching aim of this GRC is to discuss cutting edge research focused on glial cell development, functional interactions between glia and other cell types in the healthy nervous system, and the contributions of glial cells to disease and other disorders of the nervous system. The 2023 meeting will emphasize discussion of emerging studies on the cellular, physiological, and molecular interactions between glial subtypes, glia and neurons, and glia and non-neuronal cells (e.g. the immune system, vasculature, and other peripheral barriers). Through our recruitment of innovative speakers, this meeting will highlight state-of-the-art technologies that have the potential to greatly expand the ability to selectively visualize and manipulate distinct glial cell types, to gain greater insight into the diverse roles of glia in a variety of contexts. The meeting will host presentations from 45 Speakers in sessions led by 15 Discussion Leaders, representing both influential, established scientists and young investigators just beginning to embark on their independent research careers. 61% of the planned speakers are woman, and greater than 30% of the Speakers are young investigators within five years of establishing their own laboratories. 82% have already accepted (and did so within 48 hrs), highlighting the enthusiasm for this meeting. Of note, two established scientists will lead a timely and important discussion session (“Power Hour”) entitled Creating an inclusive lab environment: Preventing and addressing harassment and discrimination”. Participation by underrepresented minorities is being actively solicited and will be supported by available funds, and inclusion of investigators and trainees from all people groups, including underrepresented minorities and those with disabilities, will be a top priority. NIH support of this grant is critical to maximize trainee participation, as it funds not only the GRC, but also the trainee-led Gordon Research Seminar (GRS) on Glial Biology, which will host its 4th meeting just prior to the GRC. The GRS provides an opportunity for young scientists (graduate students and postdocs) in the field to share ideas, host a keynote speaker, and present their work in progress via platform or poster presentations to each other and the GRC chairs and keynote speaker. In both the GRC and GRS, designated sessions will focus on the development and function of glia in neural circuitry and metabolic support in both the healthy and diseased brain and the broader nervous system. The dissemination of cutting-edge research findings and extensive training opportunities for junior scientists enabled by this meeting are highly pertinent to the overall mission of the NIH and NINDS.