Immunology core

免疫学核心

• 批准号: 10609044
• 负责人: James Beeson
• 金额: $ 5.09万
• 依托单位: WALTER AND ELIZA HALL INST MEDICAL RES
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-28 至 2024-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10609044
• 关键词: Antibodies; Antigens; Asia; Biological Assay; Biological Markers; Blocking Antibodies; Blood; Cambodia; Collaborations; Communities; Complement; Custom; Data; Development; Erythrocytes; Generations; Germ Cells; Immune response; Immunity; Immunologic Factors; Immunologics; Immunology; Laboratories; Malaria; Measures; Modeling; Papua New Guinea; Parasitemia; Parasites; Plasma; Plasmodium falciparum; Predictive Factor; Procedures; Publications; Recombinant Proteins; Relapse; Research; Research Personnel; Sampling; Serology; Serology test; Serum; Site; Speed; Surface; Surface Antigens; Thailand; Training; data sharing; experience; malaria transmission; response; risk prediction; sharing platform; statistics; transmission blocking; transmission process

Summary of Immunology Core: The immunology core will provide expertise in data generation and analysis for all immunological studies as part of the Asia Pacific ICEMR. This core will interact closely with the investigators of all three Asia Pacific ICEMR projects and generate state-of-the-art immunology data to complement the research objectives. In addition, the Immunology Core will coordinate its activities with the Data Statistics and Modelling Core to facilitate integration and sharing of immunology data generated among investigators. We already have extensive experience with all experimental procedures described in this application and many of the assays have already been successfully applied to malaria parasite species. In collaboration with the Data Statistics and Modelling Core, the Immunology Core will also implement strategies to facilitate the use of the data generated by the Asia Pacific ICEMR investigators and the broader community. In particular, we will make the immunology data from the study quickly available to others by developing an immunology data sharing platform with other ICEMRs. This will greatly facilitate querying and exporting subsets of the data or set of samples and speed up analyses. These browsers will be publically available to any researcher outside the Asia Pacific ICEMR immediately upon publications.

免疫学核心概述： 免疫学核心将为所有免疫学领域的数据生成和分析提供专业知识。 作为亚太ICEMR的一部分。这个核心将与调查人员密切互动， 所有三个亚太ICEMR项目，并生成最先进的免疫学数据， 补充研究目标。此外，免疫学核心将协调其活动， 与数据统计和建模核心，以促进免疫学的整合和共享 研究者之间产生的数据。我们已经有了丰富的经验， 本申请中描述的方法和许多测定已经成功地 应用于疟疾寄生虫物种。与数据统计和建模核心合作， 免疫学核心还将实施战略，以促进使用 亚太地区ICEMR调查人员和更广泛的社区。特别是，我们将使 通过开发免疫学数据， 与其他ICEMR共享平台。这将极大地方便查询和导出 数据或样本集并加快分析速度。这些浏览器将可用于 亚太ICEMR以外的任何研究人员在发表后立即通知。