Developing a widely-useable wearable Circadian Profiling System to assess 24-hour behavioral rhythm disruption in people with dementia and their family caregivers

补充项目总结：父研究(1R41AG069596-01A1)正在进行原型制作和初步执行 一种新型可穿戴式监控系统的用户测试。这个系统，我们称之为昼夜节律活动 痴呆症治疗(CAPS-DM)的简档系统(CAPS)旨在评估24小时行为 痴呆症患者及其家庭照顾者的节律紊乱。帽子的一个用途是个性化/ 为阿尔茨海默病和相关痴呆患者家庭量身定制行为干预措施 (ADRDS)。家长奖的目的是(1)为患有ADRDS的家庭准备CAPS原型；以及(2) 评估用户的依从性/使用对健康的潜在影响。虽然我们正在按部就班地完成此范围(尽管 延迟)，则用户测试成功的可能性将显著增加 直接应对新冠肺炎疫情带来的两个挑战。这两个出乎意料的人 挑战是这一补充奖项的目的。我们建议目标1将我们对上限的审判转变为 所有远程/虚拟/在线进行。完成切换到所有远程学习管理的过程 在此之前，在ADRD用户中进行初始测试将通过以下方式增加用户测试成功的可能性：(1)确保 在新冠肺炎环境中成功注册(扩大我们的覆盖范围和参与者屏幕数量)；以及 (2)提高APP的独立能力(即，在没有得到实质性援助的情况下，对ADRD家庭有用 面对面/电话用户支持)。为了实现所有远程进行的研究，我们建议将此补充内容用于： 促进在线招聘；添加基于在线的研究评估；并使Caps App- 仅通过增强设置和教育材料来实现。第二个挑战/目标2 补充是为了解决我们的悬而未决的问题，该问题与雇佣一个兼职软件工程师 技能非常多样化。软件工程师市场正变得竞争日益激烈，因为 在新冠肺炎大流行期间，各行业的服务业都有所增加。家长奖包括谦虚 支持兼职软件开发人员，但没有足够的资金聘请具有以下独特技能的开发人员 技能：基于服务器的数据库分析和基于iPhone的用户界面/交互设计。本副刊 获奖将通过以下方式提高我们聘用合格软件开发支持的能力：(1)与 资讯科技人员编制服务；及(2)将开发工作重新分配给两名兼职开发人员， 因此不再需要应聘者在不同的工作领域(设计和服务器/数据库)拥有技能 分析)。总而言之，这一补充奖励将增加父项目被 成功的方法是确保我们能够招募ADRD用户测试员的样本；增强他们的用户- 体验与现代软件应用程序不相上下；修改我们开放式SBC的工作说明 开发人员职位，加上使用人员配备服务，以确保现实和及时的人员配备。

Supplement Project Summary: The parent study (1R41AG069596-01A1) is prototyping and performing initial user testing of a novel wearable-based monitoring system. The system, which we call the Circadian Activity Profiling System (CAPS) for Dementia Management (CAPS-DM) is designed to assess 24-hour behavioral rhythm disruption in people with dementia and their family caregivers. One use of the CAPS is to personalize/ adaptively tailor behavioral interventions for families affected by Alzheimer’s Disease and Related Dementias (ADRDs). The parent award aims to (1) prepare the CAPS prototype for use by families with ADRDs; and (2) evaluate user adherence/potential health effects of use. While we are on track to complete this scope (albeit delayed, see above), the likelihood that user testing will be successful would be substantially increased by directly addressing two challenges that were brought on by the COVID-19 pandemic. These two unanticipated challenges are the aims of this supplement award. We propose Aim 1 to transition our trial of the CAPS to be conducted all remotely/virtually/online. Completing the process of switching to all remote study administration prior to this initial test among ADRD users will increase the likelihood of a successful user test by: (1) ensuring enrollment success in the COVID-19 environment (increase our reach and number of participant screens); and (2) improving the ability of the app to “standalone” (i.e., be useful to ADRD families without substantial aid from in-person/telephone user support). To enable an all remotely conducted study, we propose this supplement to: facilitate online-based recruitment; add online-based research assessments; and make the CAPS App stand- alone through enhancements to both set up and educational materials. The second challenge/Aim 2 of this supplement is to resolve our pending issue related to hiring a single part-time software engineer with an extremely diverse skill set. The market for software engineers has becoming increasing competitive as remote services increased across industries during the COVID-19 pandemic. The parent award included modest support for a part-time software developer, but not sufficient funds to hire a developer with the following unique skills: server-based database analytics and iPhone-based user interface/interaction design. This supplement award would increase our ability to hire qualified software development support by: (1) contracting with an Information Technology staffing service; and (2) re-allocating development work to two part-time developers, thereby no longer requiring the candidate to have skills in distinct work areas (design and server/database analytics). In summary, this supplement award would increase the likelihood that the parent project is successful by ensuring that we are able to recruit the sample of ADRD user-testers; enhancing their user- experience to be on-par with modern software application; and amending job descriptions for our open SBC developer position, plus using a staffing service, to ensure realistic and timely staffing.