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LARGE SCALE T CELL EPITOPE DISCOVERY - COVID Supplement

LARGE SCALE T CELL EPITOPE DISCOVERY - COVID Supplement
大规模 T 细胞表位发现 - COVID 补充品
批准号:
10612326
负责人:
STEPHEN WILSON
金额:
$80.0万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-09-30 至 2023-09-29

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中文摘要
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英文摘要
The SARS-CoV-2 epitope Megapools (SARS-CoV-2 MPs) is used to study SARS-CoV-2 CD4 and CD8 specific T cell responses. The Megapool (MP) approach allows simultaneous testing of large number of epitopes. According to this approach large numbers of different epitopes are solubilized, pooled and re-lyophilized to avoid cell toxicity problems associated with high concentrations of DMSO typically encountered when single pre-solubilized epitopes are pooled. These MPs have been used for both CD4 and CD8 T cell epitope identification.
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LARGE SCALE T CELL EPITOPE DISCOVERY - COVID Supplement
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Infectious Diseases
  • 批准号:
    10788228
  • 项目类别:
  • 资助金额:
    $215.03万
  • 财政年份:
    2018
  • 负责人:
    STEPHEN WILSON
  • 依托单位:
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Autoimmune diseases, including SLE, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis
IMMUNE EPITOPE AND ANALYSIS PROGRAM: Infectious Diseases
  • 批准号:
    10329666
  • 项目类别:
  • 资助金额:
    $320.28万
  • 财政年份:
    2018
  • 负责人:
    STEPHEN WILSON
  • 依托单位:
海外基金