IMMUNE EPITOPE AND ANALYSIS PROGRAM: Autoimmune diseases, including SLE, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis

免疫表位和分析项目：自身免疫性疾病，包括 SLE、类风湿性关节炎、1 型糖尿病、多发性硬化症和重症肌无力

• 批准号: 10551167
• 负责人: STEPHEN WILSON
• 金额: $ 34.41万
• 依托单位: LA JOLLA INSTITUTE FOR IMMUNOLOGY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-12-15 至 2025-12-14
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10551167
• 关键词: Antibodies; Autoimmune Diseases; Communities; Contractor; Contracts; Databases; Development; Epitope Mapping; Epitopes; Immune; Insulin-Dependent Diabetes Mellitus; Link; Literature; Lupus; Multiple Sclerosis; National Institute of Allergy and Infectious Disease; Online Systems; Publishing; Resources; Rheumatoid Arthritis; Series; Systemic Lupus Erythematosus; T-Lymphocyte Epitopes; Visualization; analytical tool; improved; programs; protein structure; relational database; tool; web site

The Immune Epitope Database and Analysis Program contains extensively curated antibody and T cell epitope information from the published literature and NIAID epitope discovery contractors, as well as tools to predict antibody and T cell epitopes or visualization/mapping of epitopes onto known protein structures. Over 20,500 references have been curated into the IEDB, which includes autoimmune disease such as lupus, rheumatoid arthritis, type 1 diabetes, multiple sclerosis, and myathenia gravis. In addition, the IEDB hosts a series of epitope analysis tools.

免疫表位数据库和分析程序包含来自已发表文献和NIAID表位发现承包商的广泛策划的抗体和T细胞表位信息，以及预测抗体和T细胞表位或将表位可视化/映射到已知蛋白质结构上的工具。超过20，500篇参考文献已纳入IEDB，其中包括自身免疫性疾病，如狼疮，类风湿性关节炎，1型糖尿病，多发性硬化症和重症肌无力症。此外，IEDB还拥有一系列表位分析工具。