Postdoctoral Research Training in Alzheimer's Disease and Related Neurodegenerative Disorders

阿尔茨海默病和相关神经退行性疾病博士后研究培训

基本信息

项目摘要

This is a proposal to renew an advanced postdoctoral training program focused on Alzheimer’s disease and related neurodegenerative disorders at NYU Grossman School of Medicine. There is a critical need to train early career scientists who will investigate Alzheimer’s disease and related neurodegenerative disorders, develop new interventions, and translate these findings from bench to bedside and from bedside to community. The program will continue to be housed in the Center for Cognitive Neurology, an extra-departmental, multidisciplinary program designed to foster collaborative research, with 37 faculty members serving as mentors. The goal of the program is to endow trainees with diverse scientific backgrounds with the necessary skills, multidisciplinary approaches, and rigorous methodologies to advance the field of Alzheimer’s disease and related neurodegenerative disorders. This renewal application expands our current training program by appointing exceptional cognitive neurology clinician-scientist researchers. We will build on our previous training program by appointing three postdoctoral trainees and one cognitive neurology fellow from a well-qualified pool of MD, MD/PhD, and PhD applicants. As per the NIH recommendation for postdoctoral research training, the trainees will be appointed for two years and will continue to receive mentoring and career development support in subsequent years. The program's goals to train these fellows will be accomplished through a tailored curriculum that includes training in rigorous research techniques and quantitative analysis, enhanced mentorship, didactics in foundational concepts, honing science communication skills, and career planning. This training program enables postdoctoral fellows to prepare for the intensely collaborative and interdisciplinary nature of modern research by providing: (a) high-quality scientific training in the area of Alzheimer’s disease and related neurodegenerative disorders, clinical approaches, statistical analyses, and rigorous experimental design; (b) enhanced mentoring that aids trainees’ progress toward future careers in science, and (c) training in the professional skills that are necessary for success in academic research, including critical reading, grant writing, oral presentation, leadership, management, and networking. The training of the next generation of research and clinician scientists with expertise in Alzheimer’s disease and related neurodegenerative disorders is, and will remain, a public health priority in the United States for many years to come. Our collaborative T32 program supports these early scientists as they launch their independent and successful careers in this critical field.
这是纽约大学格罗斯曼医学院关于阿尔茨海默病和相关神经退行性疾病的高级博士后培训计划的提议。迫切需要培养早期职业科学家,他们将研究阿尔茨海默病和相关的神经退行性疾病,开发新的干预措施,并将这些发现从实验室应用到临床,从临床应用到社区。该项目将继续设在认知神经学中心,这是一个旨在促进合作研究的跨部门多学科项目,有37名教师担任导师。该计划的目标是赋予具有不同科学背景的受训者必要的技能,多学科方法和严格的方法,以推进阿尔茨海默病和相关神经退行性疾病领域。这项更新申请通过任命杰出的认知神经学临床科学家研究人员扩展了我们目前的培训计划。我们将在之前的培训计划的基础上,从合格的医学博士、医学博士/博士和博士申请者中任命三名博士后培训生和一名认知神经学研究员。根据NIH对博士后研究培训的建议,受训者将被任命两年,并将在随后的几年中继续获得指导和职业发展支持。该项目的培训目标将通过量身定制的课程来实现,其中包括严格的研究技术和定量分析方面的培训,加强指导,基本概念的教学,磨练科学沟通技巧和职业规划。该培训计划通过提供:(a)阿尔茨海默病和相关神经退行性疾病、临床方法、统计分析和严格的实验设计领域的高质量科学培训,使博士后能够为现代研究的紧密合作和跨学科性质做好准备;(b)加强指导艾滋病受训者在未来科学事业中的进步,以及(c)在学术研究中取得成功所必需的专业技能方面的培训,包括批判性阅读、拨款写作、口头陈述、领导能力、管理和网络。培训具有阿尔茨海默病和相关神经退行性疾病专业知识的下一代研究和临床科学家是,并将继续是未来许多年美国公共卫生的优先事项。我们的合作T32计划支持这些早期科学家在这一关键领域开展独立和成功的职业生涯。

项目成果

期刊论文数量(6)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Helen E Scharfman其他文献

Helen E Scharfman的其他文献

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{{ truncateString('Helen E Scharfman', 18)}}的其他基金

Mossy cells in temporal lobe epilepsy
颞叶癫痫中的苔藓细胞
  • 批准号:
    10586664
  • 财政年份:
    2023
  • 资助金额:
    $ 33.1万
  • 项目类别:
The Role of Hippocampal area CA2 in Epilepsy
海马区 CA2 在癫痫中的作用
  • 批准号:
    10745170
  • 财政年份:
    2018
  • 资助金额:
    $ 33.1万
  • 项目类别:
Hyperexcitability in Alzheimer's Disease
阿尔茨海默病的过度兴奋
  • 批准号:
    9905338
  • 财政年份:
    2017
  • 资助金额:
    $ 33.1万
  • 项目类别:
Postdoctoral Research Training in Neurodegenerative Disorders and the Aging Brain
神经退行性疾病和大脑老化的博士后研究培训
  • 批准号:
    9279591
  • 财政年份:
    2017
  • 资助金额:
    $ 33.1万
  • 项目类别:
Hyperexcitability in Alzheimer's Disease
阿尔茨海默病的过度兴奋
  • 批准号:
    9263112
  • 财政年份:
    2017
  • 资助金额:
    $ 33.1万
  • 项目类别:
Postdoctoral Research Training in Neurodegenerative Disorders and the Aging Brain
神经退行性疾病和大脑老化的博士后研究培训
  • 批准号:
    10176313
  • 财政年份:
    2017
  • 资助金额:
    $ 33.1万
  • 项目类别:
Postdoctoral Research Training in Alzheimer's Disease and Related Neurodegenerative Disorders
阿尔茨海默病和相关神经退行性疾病博士后研究培训
  • 批准号:
    10411200
  • 财政年份:
    2017
  • 资助金额:
    $ 33.1万
  • 项目类别:
Hilar mossy cells and dentate gyrus function
肺门苔藓细胞和齿状回功能
  • 批准号:
    9321241
  • 财政年份:
    2016
  • 资助金额:
    $ 33.1万
  • 项目类别:
Diverse Roles of Adult Dentate Gyrus Neurogenesis
成人齿状回神经发生的多种作用
  • 批准号:
    8668177
  • 财政年份:
    2013
  • 资助金额:
    $ 33.1万
  • 项目类别:
Diverse Roles of Adult Dentate Gyrus Neurogenesis
成人齿状回神经发生的多种作用
  • 批准号:
    8824981
  • 财政年份:
    2013
  • 资助金额:
    $ 33.1万
  • 项目类别:

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新型F-18标记香豆素衍生物PET探针的研制及靶向Alzheimer's Disease 斑块显像研究
  • 批准号:
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  • 批准年份:
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  • 批准年份:
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    地区科学基金项目
跨膜转运蛋白21(TMP21)对引起阿尔茨海默病(Alzheimer'S Disease)的γ分泌酶的作用研究
  • 批准号:
    30960334
  • 批准年份:
    2009
  • 资助金额:
    22.0 万元
  • 项目类别:
    地区科学基金项目

相似海外基金

Pathophysiological mechanisms of hypoperfusion in mouse models of Alzheimer?s disease and small vessel disease
阿尔茨海默病和小血管疾病小鼠模型低灌注的病理生理机制
  • 批准号:
    10657993
  • 财政年份:
    2023
  • 资助金额:
    $ 33.1万
  • 项目类别:
Social Connectedness and Communication in Parents with Huntington''s Disease and their Offspring: Associations with Psychological and Disease Progression
患有亨廷顿病的父母及其后代的社会联系和沟通:与心理和疾病进展的关联
  • 批准号:
    10381163
  • 财政年份:
    2022
  • 资助金额:
    $ 33.1万
  • 项目类别:
The Role of Menopause-Driven DNA Damage and Epigenetic Dysregulation in Alzheimer s Disease
更年期驱动的 DNA 损伤和表观遗传失调在阿尔茨海默病中的作用
  • 批准号:
    10531959
  • 财政年份:
    2022
  • 资助金额:
    $ 33.1万
  • 项目类别:
The Role of Menopause-Driven DNA Damage and Epigenetic Dysregulation in Alzheimer s Disease
更年期驱动的 DNA 损伤和表观遗传失调在阿尔茨海默病中的作用
  • 批准号:
    10700991
  • 财政年份:
    2022
  • 资助金额:
    $ 33.1万
  • 项目类别:
Interneurons as early drivers of Huntington´s disease progression
中间神经元是亨廷顿病进展的早期驱动因素
  • 批准号:
    10518582
  • 财政年份:
    2022
  • 资助金额:
    $ 33.1万
  • 项目类别:
Interneurons as Early Drivers of Huntington´s Disease Progression
中间神经元是亨廷顿病进展的早期驱动因素
  • 批准号:
    10672973
  • 财政年份:
    2022
  • 资助金额:
    $ 33.1万
  • 项目类别:
Social Connectedness and Communication in Parents with Huntington''s Disease and their Offspring: Associations with Psychological and Disease Progression
患有亨廷顿病的父母及其后代的社会联系和沟通:与心理和疾病进展的关联
  • 批准号:
    10585925
  • 财政年份:
    2022
  • 资助金额:
    $ 33.1万
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Oligodendrocyte heterogeneity in Alzheimer' s disease
阿尔茨海默病中的少突胶质细胞异质性
  • 批准号:
    10180000
  • 财政年份:
    2021
  • 资助金额:
    $ 33.1万
  • 项目类别:
Serum proteome analysis of Alzheimer´s disease in a population-based longitudinal cohort study - the AGES Reykjavik study
基于人群的纵向队列研究中阿尔茨海默病的血清蛋白质组分析 - AGES 雷克雅未克研究
  • 批准号:
    10049426
  • 财政年份:
    2021
  • 资助金额:
    $ 33.1万
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Repurposing drugs for Alzheimer´s disease using a reverse translational approach
使用逆翻译方法重新利用治疗阿尔茨海默病的药物
  • 批准号:
    10295809
  • 财政年份:
    2021
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    $ 33.1万
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