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CORE C Rabadan

CORE C Rabadan
核心C拉巴丹
批准号：
10614999
负责人：
Raul Rabadan
金额：
$15.1万
依托单位：
COLUMBIA UNIVERSITY HEALTH SCIENCES
依托单位国家：
美国
项目类别：
财政年份：
2014
资助国家：
美国
项目状态：
未结题
起止时间：
2014-04-08 至 2025-03-31
来源：
https://reporter.nih.gov/project-details/10614999
关键词：
BiometryCalibrationChromatinChromosomal translocationClassificationCollaborationsComputational TechniqueComputing MethodologiesDNA Double Strand BreakDNA RepairDNA Sequence AlterationDataData AnalysesData SetDevelopmentDouble Strand Break RepairEpigenetic ProcessGenetic TranscriptionGenomicsGerm-Line MutationGoalsLeadershipLearningMachine LearningMalignant NeoplasmsMathematicsMethodsModelingMutationPhysicsPoint MutationPortraitsPositioning AttributeProductivityResearchRoleScientistSourceStructureTechniquesTechnologyTestingTrainingUniversitiesXCL1 geneanalysis pipelineblindcomplex datacomputational pipelinescomputer sciencedata integrationdeep learningexperimental studygenome-widegenomic datainsertion/deletion mutationmembernovelstatisticstheoriestooltraining opportunitytranscriptomicstumorwhole genome

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中文摘要
翻译
摘要 基因组技术正在彻底改变癌症和癌症中DNA变化的特征 它们与不同的DNA修复机制有关。计算基因组学核心提供了 集中结构，收集、分析和整合所有四个项目的数据。除了……之外 目前已经实现的计算管道，核心将开发新的技术， 将跨项目应用，它将实现数据集成的方法，提供量化 在统计问题上提供培训和建议。
英文摘要
Summary Genomic techniques are revolutionizing the characterization of DNA alterations in cancer and their relation to different DNA repair mechanisms. The Computational Genomics Core provides a centralized structure to collect, analyzed and integrate data from all four projects. In addition to current already implemented computational pipelines, the core will develop new techniques that will be applied across projects, it will implement methods for data integration, provide quantitative training and advise in statistical questions.
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