Translating Scientific Evidence into Practice using Digital Medicine and Electronic Patient Reported Outcomes

使用数字医学和电子患者报告结果将科学证据转化为实践

• 批准号: 10615922
• 负责人: Ashish Atreja
• 金额: $ 119.27万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-04-20 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10615922
• 关键词: Address; Adopted; Adoption; American; Behavioral; Body Weight decreased; Caring; Cellular Phone; Clinic; Clinical; Clinical Sciences; Clinical Trials; Cluster randomized trial; Collaborations; Colorectal Surgery; Communities; Development; Diarrhea; Disease; Disparity; Effectiveness; Electronic Health Record; Emergency Care; Emergency Situation; Emergency department visit; Emotional; Evaluation; Family; Funding; Geographic Locations; Goals; Health; Health education; Health system; Healthcare; Hemorrhage; Home; Hospitalization; Illinois; Inflammatory Bowel Diseases; Institutional Review Boards; Intervention; Laboratories; Learning; Mainstreaming; Measures; Medical; Modeling; Monitor; New York; Office Visits; Ohio; Operative Surgical Procedures; Outcome; Patient Monitoring; Patient Outcomes Assessments; Patient-Focused Outcomes; Patients; Persons; Population; Population Heterogeneity; Process; Provider; Quality of Care; Quality of life; Recommendation; Rectum; Research; Research Design; Research Personnel; Resources; Science; Site; Social support; Societies; Symptoms; Technology; Telemedicine; Telephone; Testing; Text; Time; Training; Translating; Translational Research; United States National Institutes of Health; Visit; Voice; Work; behavioral health; care delivery; chronic inflammatory disease; clinical practice; cloud based; cloud platform; cohort; colorectal cancer risk; dashboard; design; digital; digital health; digital medicine; digital technology; digital treatment; disorder control; electronic consent; electronic patient reported outcomes; evidence base; health assessment; health care delivery; hospital readmission; implementation science; improved; improved outcome; inflammatory marker; innovation; lens; medical specialties; mobile application; multidisciplinary; novel; nutrition; population health; primary outcome; provider adoption; rectal; remote monitoring; research study; response; skills; social; social determinants; tool; urgent care

Project Summary: Delivery of healthcare has been traditionally limited to in-person office visits or hospitalizations, while patients spent the majority of their time at home or work. Digital Medicine (e.g. apps, remote monitoring, telemedicine, patient reported outcomes [ePRO]) has the potential to bridge this gap, but it is unclear how to implement in a mainstream clinical practice that can lead to high-level patient and provider adoption. Through the creation of a Digital Transformation Network (DTN) for Inflammatory Bowel Disease (IBD), we plan to reduce digital disparities and scientifically address the evidence gap of digital health interventions across populations and communities. AIM I. Unify existing digital assets (mobile app, ePROs, assessment for digital disparities and behavioral health, referral to IBD home and health education) into an IBD Digital Therapeutics Toolkit and integrate with EHRs at 3 CTSA hubs. Hypothesis: Integration with EHRs will lead to higher adoption by providers and limit disruption of workflow. AIM II: Establish baseline levels of digital connectivity, disease control, quality of life and care metrics in cohorts at the three IBD centers. Hypothesis: A multipronged approach of assessment through text, phone, an app, and in-person will yield higher adoption. AIM III. Implement and evaluate precision-matched interventions (digital skills, social determinants, behavioral health, monitoring through apps, and referral to interdisciplinary care) among 1500 patients with IBD using a stepped-wedge, cluster- randomized trial. Hypothesis: Medical homes supported by a unified platform will translate to sustainable improvement in population health outcomes. Analyze the Impact of DTN interventions. The primary outcome will be the improvement of the percentage of patients in DTN in disease control and decrease in urgent care utilization (emergency department visits and hospitalization days) across the three CTSA sites. AIM IV. Support sustainability and dissemination across CTSA sites. Hypothesis: The patient- centric DTN will be sustainable through alignment with value-based healthcare. Anticipated Impact: About 2 million Americans suffer from IBD and many more with chronic inflammatory diseases. We hope that this study will help us build an evidence-based approach to determine whether digital medicine can engage a diverse group of patients and improve outcomes; and if yes, how it can be reproduced and replicated across different settings to address theT3 and T4 translational gaps.

项目总结:

项目成果

Pre-existing Disparities and Potential Implications for the Rapid Expansion of Telemedicine in Response to the Coronavirus Disease 2019 Pandemic.

• DOI: 10.1097/mlr.0000000000001585
• 发表时间: 2021-08-01
• 期刊: Medical care
• 影响因子: 3
• 作者: Poeran J;Cho LD;Wilson L;Zhong H;Mazumdar M;Liu J;Memtsoudis SG
• 通讯作者: Memtsoudis SG

Getting ready for real-world use of electronic patient-reported outcomes (ePROs) for patients with cancer: A National Comprehensive Cancer Network ePRO Workgroup paper.

为癌症患者在现实世界中使用电子患者报告结果 (ePRO) 做好准备：国家综合癌症网络 ePRO 工作组论文。

• DOI: 10.1002/cncr.34844
• 发表时间: 2023
• 期刊: Cancer
• 影响因子: 6.2
• 作者: Cracchiolo,JenniferR;Arafat,Waddah;Atreja,Ashish;Bruckner,Lauren;Emamekhoo,Hamid;Heinrichs,Tricia;Raldow,AnnC;Smerage,Jeffrey;Stetson,Peter;Sugalski,Jessica;Tevaarwerk,AmyeJ
• 通讯作者: Tevaarwerk,AmyeJ