Indiana Pediatric Scientist Award (IPSA)

项目摘要/摘要-印第安纳州儿科科学家奖(IPSA) 迫切需要通过正规教育和培训来培养下一代内科科学家 在儿童健康方面。挑战仍然存在于初级教员队伍的整体萎缩和种族范围的扩大 和劳动力的性别多样性。没有训练有素的调查人员，谁能突破当前的极限 科学知识，将改变儿童和青少年健康的尖端研究的目标不能 被实现了。印第安纳大学儿科系在满足这一需求方面具有独特的地位。一个 科研院所中一批强大的、久负盛名的基础科学研究人员具有以下优势 紧邻莱利儿童医院，是世界上唯一的综合性儿童医院。 印第安纳州。印第安纳大学医学院(IUSM)的儿科一直是 在NIH资金方面排名前十，其NIH投资组合在过去8年中翻了一番以上。儿科 IUSM的研究人员在传染病、糖尿病、 Rasopathy和其他遗传性疾病越来越多地出现在床边科学上，包括 改变用途或产生有针对性的治疗方法。IUSM和莱利儿童基金会已经 提供了招聘杰出研究人员所需的广泛资源 学员的专业发展。这种支持使我们的战略和系统增加了 整个流水线发展，包括K资助初级教员的显著增加。在现有的 雄厚的体制基础，我们寻求支持，进一步扩大对内对外发展 在IUSM招募了一群范围广泛的儿科研究人员。印第安纳大学的主要目标 医学院的印第安纳州儿科科学家奖(IPSA)培训计划是为研究人员提供 致力于追求学术儿科医生的职业生涯，科学家具有严谨和个性化的 指导研究经验，使每个受训者都能获得竞争性的个人指导职业奖项。 目前的计划是专门为儿科内科科学家设计的，并提供了一个既定的 成功的蓝图，包括结构化的指导、指导和进步目标，以实现 独立资助。因此，IPSA方案将提供定制的、多学科的指导 关注个人的学习风格、背景和兴趣。支持将允许IUSM 儿科继续扩大一个快速增长的，多方面的项目，并招聘一名有才华的， 不同的儿科医生-科学家培训生队列，开展基础和转化性研究，将 最终揭示疾病的发病机制，改变儿童的医疗保健。

PROJECT SUMMARY/ABSTRACT – Indiana Pediatric Scientist Award (IPSA) A critical need exists for training the next generation of physician scientists with formal education and training in child health. Challenges remain in an overall shrinking pipeline of junior faculty and in broadening the racial and gender diversity of the workforce. Without highly trained investigators, who can stretch the limits of current scientific knowledge, the goal of cutting-edge research that will transform child and adolescent health cannot be realized. The Indiana University Department of Pediatrics is uniquely positioned to address this need. A strong, well-established group of basic science investigators in a Departmental Institute have the advantage of being located directly adjacent to Riley Hospital for Children, the only comprehensive children's hospital in the state of Indiana. The Department of Pediatrics at Indiana University School of Medicine (IUSM) is consistently ranked in the top 10 in NIH funding and its NIH portfolio has more than doubled in the past 8 years. Pediatric researchers at IUSM have established international reputations in the fields of infectious disease, diabetes, Rasopathies and other genetic diseases with an increasing signature of bench to bedside science including repurposing or generating targeted therapeutics. The IUSM and the Riley Children's Foundation have provided extensive resources necessary for the recruitment of distinguished research faculty and the professional development of trainees. This support has allowed a strategic and systematic increase in our entire pipeline development, including a striking increase in K funded junior faculty. Working within this existing strong institutional foundation, we seek support to further expand the development of an internal and externally recruited group of broadly diverse pediatric researchers at IUSM. The main objective of the Indiana University School of Medicine's Indiana Pediatric Scientist Award (IPSA) training program is to provide investigators committed to pursuing careers as academic pediatric physician scientists with a rigorous and individualized mentored research experience that elevates each trainee for competitive individual mentored career awards. The current program is designed specifically for pediatric physician scientists and provides an established blueprint for success, including structured mentorship, guidance, and progressive goals in order to achieve independent funding. Consequently, the IPSA program will provide a customized, multi-disciplinary mentorship with attention to individual learning styles, backgrounds, and interests. Support will allow the IUSM Department of Pediatrics to continue to expand a rapidly growing, multifaceted program and recruit a talented, diverse cohort of pediatric physician-scientist trainees to carry out basic and translational research that will ultimately inform disease pathogenesis and transform health care for children.