2023 Salivary Glands and Exocrine Biology GRC and GRS

项目摘要 该提案要求部分支持第十三届戈登研究会议（GRC）和第三届 戈登研究研讨会（GRS）题为唾液腺和外分泌生物学：了解生物学的 外分泌组织的分泌功能和疾病将于2023年1月29日至2月3日在 加州文图拉的福朋喜来登酒店。GRC将包括外分泌腺全体会议 发育，再生方法，唾液蛋白的功能相关性， 外分泌腺，了解自身免疫性疾病的病因，靶向炎症以延缓疾病 发病机制和目前的主题外分泌腺：病原体，如SARS冠状病毒2的相互作用。特邀发言者 因为GRC将包括来自学术界、工业界和政府的杰出科学家，会谈将包括 来自不同领域的高级和初级科学家，他们将展示当前未发表的研究成果 前几次会议的组织者和与会者认为实地最感兴趣的项目。几个基调 研讨会将邀请讲者就干细胞疗法、临床基因组学及临床试验， 干燥病，一种常见的自身免疫性疾病，影响外分泌腺，并对 无法获得适当和有效治疗的患者的生活质量。其中一个值得注意的特点是， GRC将是在2017年首次提供的GRC之前举行的GRS的延续，仅邀请 演讲者是世界各地各种实验室的研究生和博士后研究员。 这些在GRS的年轻科学家也将参加GRC，其中许多人将被选中举办研讨会 将列入全体会议。此外，政府资源中心每天都会举行海报张贴会， 所有与会者在一个开放的论坛上展示和讨论他们的数据。GRC和GRS的总体目标是 促进科学交流，并在被视为具有竞争力的学科中开展研究合作。 对发展改善人类健康的新战略产生重大影响。具体目标符合 NIDCR的使命包括：1）向学术界、工业界和 政府和聚集初级和高级调查人员在一个愉快的环境，他们将有 有机会在知识渊博的观众面前讨论未发表的研究结果，并参与广泛的 关键的研究讨论; 2）提供研究生和博士后助理参加的GRS 他们将在同龄人面前展示他们的新研究成果; 3）强调 介绍了外分泌生物学领域感兴趣的最新方法， 开发创新方法，通过预防分泌失调来改善人类健康 机关

PROJECT SUMMARY This proposal requests partial support for the thirteenth Gordon Research Conference (GRC) and the third Gordon Research Seminar (GRS) entitled Salivary Glands and Exocrine Biology: Understanding the Biology of Secretory Function and Diseases of Exocrine Tissues to be held from Back January 29th-February 3rd, 2023, at the Four Points Sheraton hotel in Ventura, CA. The GRC will include plenary sessions on exocrine gland development, regenerative approaches, functional relevance of salivary proteins, membrane functions in exocrine glands, understanding the etiology of autoimmune disease, targeting inflammation to retard disease pathogenesis and current topics in exocrine gland:pathogen such as SARS-CoV2 interactions. Invited speakers for the GRC will include eminent scientists from academia, industry and government and talks will include both senior and junior scientists from diverse fields who will present current unpublished research findings on subjects identified by previous meeting organizers and attendees as of greatest interest to the field. Several keynote speakers will be invited to deliver seminars on stem cell therapeutics, clinical genomics and clinical trials for Sjögren's disease, a common autoimmune disease that affects exocrine glands and negatively impacts the quality of life of patients for whom no suitable and effective therapies are available. A noteworthy feature of this GRC will be continuation of a GRS to be held just prior to the GRC, first offered in 2017, that will invite only speakers who are graduate students and postdoctoral associates in a wide variety of laboratories worldwide. These junior scientists at the GRS will also attend the GRC where many of them will be chosen to give seminars that will be included in the plenary sessions. In addition, poster sessions will be held daily at the GRC to enable all attendees to present and discuss their data in an open forum. The overall goal of the GRC and GRS will be to foster scientific exchanges and engender research collaborations in disciplines that are viewed as having a major impact on the development of novel strategies to improve human health. Specific Aims in line with the NIDCR mission include: 1) to present a program of topical interest to scientists in academia, industry and government and to assemble junior and senior investigators in a pleasant setting where they will have opportunities to discuss unpublished findings before a knowledgeable audience and engage in a wide range of critical research discussions; 2) to offer a GRS to be attended by graduate students and postdoctoral associates who will present their novel research findings before an audience of their peers and; 3) to emphasize presentations on state-of-the-art methodologies of interest to the exocrine biology field towards the goal of developing innovative approaches to the improvement of human health by preventing disorders of secretory organs.