Novel molecular regulators of pregnancy success

妊娠成功的新型分子调节剂

• 批准号: nhmrc : 565320
• 负责人: E/Pr Eugenie Lumbers
• 金额: $ 33.05万
• 依托单位: The University of Adelaide
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Project Grants
• 财政年份: 2009
• 资助国家: 澳大利亚
• 起止时间: 2009-01-01 至 2011-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/novel-molecular-regulators-pregnancy-success/76251
• 关键词: Novel; molecular; regulators; pregnancy; success

The main complications of pregnancy, preeclampsia, preterm birth and intrauterine growth restriction affliict 19% of first pregnancies and are life threatening to the mother or baby in 6% of pregnancies. They are associated with poor placental invasion of the uterus. We aim to further elucidate the molecular mechanisms involved in placental invasion and proper placental development to identify possible targets for future treatments to improve the health of pregnant women and babies.

妊娠的主要并发症，先兆子痫、早产和宫内生长受限困扰着19%的首次妊娠，并在6%的妊娠中危及母亲或婴儿的生命。它们与胎盘侵袭子宫不良有关。我们的目标是进一步阐明参与胎盘侵袭和胎盘正常发育的分子机制，以确定未来治疗的可能靶点，以改善孕妇和婴儿的健康。