Administrative Core

行政核心--项目摘要 行政核心(AC)的目的是提供组织、行政和财务 管理这一P01，制定和实施监测进展的计划，并有效地 在P01内部进行协调和沟通。AC对于确保该计划项目能够 在所有合作机构成功开展临床研究、物理和生物研究。 在这种规模和意义的复杂、多地点计划中成功进行研究需要 集中科学监督和行政监督。 行政核心的目标是：(1)提供集中的科学和行政监督， 为所有项目和核心提供管理和文书支持；组织和指导内部指导 委员会(ISC)和年度外部咨询委员会(EAB)会议；并为周刊提供支助， 每月举行和按需举行电话和网络在线会议。(2)制定和实施计划 有效协调研究；促进交换材料(如生物样本)、数据、模型 和信息；协调研究人员之间的沟通；监测进展情况；向 ISC、EAB和NCI在适当的时间间隔。(三)提供财政管理支持和财务控制 为个别项目和核心提供服务，以确保资金得到适当使用并提供援助 人事管理所需。 P01 MPI的Theodore Hong博士(MGH)和Radhe Mohan博士(MDACC)将指导这一核心和审查 取得进展并决定与研究优先事项有关的政策事项。外部咨询委员会，由以下人员组成 该领域的顶尖科学家将每年与调查人员会面，审查科学进展和方向 研究并为下一年提出建议。ISC，由高素质的高级人员组成 MGH和MDACC的教职员工将每年开会两次，并提供反馈并确保资源用于 进行拟议的研究是可以获得的。将有无数定期安排的科学和 召开行政会议，协调参与的多个机构的活动，以促进研究和 监控进度。

ADMINISTRATIVE CORE - PROJECT SUMMARY The purpose of Administrative Core (AC) is to provide the organizational, administrative and fiscal management of this P01, to develop and implement plans for monitoring the progress, and to effectively coordinate and communicate within the P01. The AC is essential to ensure that this Program Project is able to successfully conduct clinical studies and physics and biological research at all the collaborating institutions. Successful conduct of research in a complex, multi-site program of this magnitude and significance requires centralized scientific and administrative oversight. Aims of the Administrative Core are: (1) Provide centralized scientific and administrative oversight, management and clerical support to all Projects and Cores; organize and conduct the Internal Steering Committee (ISC) and the annual External Advisory Board (EAB) meetings; and provide support for the weekly, monthly and as-needed telephone and web-based online conferences. (2) Develop and implement plans for effective coordination of research; facilitate the exchange of materials (e.g., biological samples), data, models and information; coordinate communication among researchers; monitor progress; and report progress to the ISC, EAB and the NCI at appropriate intervals. (3) Provide fiscal management support and financial control services to individual projects and cores to ensure funds are expended appropriately and provide aid as needed for personnel management. Drs. Theodore Hong (MGH) and Radhe Mohan (MDACC), the P01 MPIs, will direct this Core and review progress and decide policy matters relating to research priorities. The External Advisory Board, comprised of top scientists in the field, will meet with investigators annually to review scientific progress and the direction of research and make recommendations for the following year. The ISC, composed of the highly qualified senior faculty at MGH and MDACC, will meet twice annually and will provide feedback and ensure that resources for the conduct of the proposed research are available. There will be numerous regularly scheduled scientific and administrative meetings to coordinate activities at the multiple institutions involved to facilitate research and monitor progress.