Administrative Core

行政核心-项目摘要 行政核心（AC）的目的是提供组织，行政和财政 管理本P01，制定和实施监控进度的计划，并有效地 在P01中进行协调和沟通。AC对于确保本计划项目能够 在所有合作机构成功开展临床研究以及物理和生物研究。 在如此规模和重要性的复杂、多地点项目中成功开展研究， 集中的科学和行政监督。 行政核心的目标是：（1）提供集中的科学和行政监督， 为所有项目和核心提供管理和文书支持;组织和进行内部指导 委员会（ISC）和外部咨询委员会（EAB）年度会议;并为每周会议提供支持， 每月和根据需要举行电话和网络在线会议。(2)制定和实施计划， 有效协调研究;促进材料交流（例如，生物样本）、数据、模型 信息;协调研究人员之间的沟通;监测进展情况;并向 ISC、EAB和NCI在适当的时间间隔。(3)提供财务管理支持和财务控制 为单个项目和核心项目提供服务，以确保资金得到适当使用，并提供援助， 需要人事管理。 Drs. P01 MPI西奥多洪（MGH）和Radhe Mohan（MDACC）将指导本核心并审查 并决定与研究优先次序有关的政策事宜。外部咨询委员会由以下人员组成： 该领域的顶尖科学家将每年与研究人员会面，审查科学进展和发展方向。 研究并为明年提出建议。ISC由高素质的高级管理人员组成， 在MGH和MDACC的教师，将每年举行两次会议，并将提供反馈，并确保资源， 进行拟议的研究。将有许多定期安排的科学和 举行行政会议，协调所涉多个机构的活动，以促进研究， 监测进展情况。

ADMINISTRATIVE CORE - PROJECT SUMMARY The purpose of Administrative Core (AC) is to provide the organizational, administrative and fiscal management of this P01, to develop and implement plans for monitoring the progress, and to effectively coordinate and communicate within the P01. The AC is essential to ensure that this Program Project is able to successfully conduct clinical studies and physics and biological research at all the collaborating institutions. Successful conduct of research in a complex, multi-site program of this magnitude and significance requires centralized scientific and administrative oversight. Aims of the Administrative Core are: (1) Provide centralized scientific and administrative oversight, management and clerical support to all Projects and Cores; organize and conduct the Internal Steering Committee (ISC) and the annual External Advisory Board (EAB) meetings; and provide support for the weekly, monthly and as-needed telephone and web-based online conferences. (2) Develop and implement plans for effective coordination of research; facilitate the exchange of materials (e.g., biological samples), data, models and information; coordinate communication among researchers; monitor progress; and report progress to the ISC, EAB and the NCI at appropriate intervals. (3) Provide fiscal management support and financial control services to individual projects and cores to ensure funds are expended appropriately and provide aid as needed for personnel management. Drs. Theodore Hong (MGH) and Radhe Mohan (MDACC), the P01 MPIs, will direct this Core and review progress and decide policy matters relating to research priorities. The External Advisory Board, comprised of top scientists in the field, will meet with investigators annually to review scientific progress and the direction of research and make recommendations for the following year. The ISC, composed of the highly qualified senior faculty at MGH and MDACC, will meet twice annually and will provide feedback and ensure that resources for the conduct of the proposed research are available. There will be numerous regularly scheduled scientific and administrative meetings to coordinate activities at the multiple institutions involved to facilitate research and monitor progress.